Human NKp30/NCR3 Antibody | R&D Systems MAB1849-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NKp30/NCR3 Antibody

catalog :

MAB1849-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

210845

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments, mass cytometry

more info or order :

R&D Systems product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
mass cytometry; human; loading ...; fig 2d blocking or activating experiments; human; 5 ug/ml; loading ...; fig 4a	Jiang Z, Qin L, Tang Y, Liao R, Shi J, He B, et al. Human induced-T-to-natural killer cells have potent anti-tumour activities. Biomark Res. 2022;10:13 pubmed publisher
	Chimienti R, Baccega T, Torchio S, Manenti F, Pellegrini S, Cospito A, et al. Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for β cell replacement. Cell Rep. 2022;40:111423 pubmed publisher
	Kim N, Kim M, Cho Y, Chen W, Lee K, Kim H. PVR and ICAM-1 on Blast Crisis CML Stem and Progenitor Cells with TKI Resistance Confer Susceptibility to NK Cells. Cancers (Basel). 2020;12: pubmed publisher
	Djaoud Z, Guethlein L, Horowitz A, Azzi T, Nemat Gorgani N, Olive D, et al. Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and ?? T cells. J Exp Med. 2017;214:1827-1841 pubmed publisher
	Salimi M, Xue L, Jolin H, Hardman C, Cousins D, McKenzie A, et al. Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production. J Immunol. 2016;196:45-54 pubmed publisher
	Herrmann J, Berberich H, Hartmann J, Beyer S, Davies K, Koch J. Homo-oligomerization of the activating natural killer cell receptor NKp30 ectodomain increases its binding affinity for cellular ligands. J Biol Chem. 2014;289:765-77 pubmed publisher
	Shi J, Tricot G, Garg T, Malaviarachchi P, Szmania S, Kellum R, et al. Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma. Blood. 2008;111:1309-17 pubmed
	Warren H, Bettadapura J. A novel binding assay to assess specificity of monoclonal antibodies. J Immunol Methods. 2005;305:33-8 pubmed
	Warren H, Jones A, Freeman C, Bettadapura J, Parish C. Evidence that the cellular ligand for the human NK cell activation receptor NKp30 is not a heparan sulfate glycosaminoglycan. J Immunol. 2005;175:207-12 pubmed

product information

master code :

MAB1849

SKU :

MAB1849-100

product name :

Human NKp30/NCR3 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human NKp30/NCR3 Antibody from R&D Systems is a mouse monoclonal antibody to NKp30/NCR3. This antibody reacts with human,insect,moth - trichoplusia ni (cabbage looper),mouse. The Human NKp30/NCR3 Antibody has been validated for the following applications: Flow Cytometry,ELISA Development,Epitope Mapping,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Agonist Activity,CyTOF-ready.

target :

NKp30/NCR3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

210845

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse T cell hybridoma transfected with human NKp30/NCR3 and Mouse myeloma cell line NS0-derived recombinant human NKp30 Fc Chimera

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Insect,Moth - Trichoplusia ni (Cabbage Looper),Mouse

specificity :

Detects human NKp30/NCR3 on cell transfectants and peripheral blood NK cells.

gene symbol :

NCR3

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Human NKp30 Antibody Induces IFN-? Secretion antibody in NK-92 Cells.

applications :

Flow Cytometry,ELISA Development,Epitope Mapping,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Agonist Activity,CyTOF-ready

extended description :

Clone 210845 was used by HLDA to establish CD designation

USD :

459 USD

product details :

Clone 210845 was used by HLDA to establish CD designation

alt names :

Activating natural killer receptor p30, CD337, CD337 antigen, CD337activating NK-A1 receptor, LY117,1C7NK-p30, lymphocyte antigen 117, natural cytotoxicity triggering receptor 3, Natural killer cell p30-related protein, NCR3, NKP30, NKp30MALS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage