product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human KIR2DS4/CD158i Antibody
catalog :
MAB1847
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
179315
reactivity :
human
application :
western blot, flow cytometry
more info or order :
citations: 6
Reference
Wang J, Chai Q, Lei Z, Wang Y, He J, Ge P, et al. LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis. EMBO Mol Med. 2024;16:1755-1790 pubmed publisher
Mikhailova V, Grebenkina P, Khokhlova E, Davydova A, Salloum Z, Tyshchuk E, et al. Pro- and Anti-Inflammatory Cytokines in the Context of NK Cell-Trophoblast Interactions. Int J Mol Sci. 2022;23: pubmed publisher
Sim M, Rajagopalan S, Altmann D, Boyton R, Sun P, Long E. Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Walker D, Tang T, Lue L. Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brains. Exp Neurol. 2018;309:91-106 pubmed publisher
Kennedy P, Chazara O, Gardner L, Ivarsson M, Farrell L, Xiong S, et al. Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy. J Immunol. 2016;197:4292-4300 pubmed
Beziat V, Descours B, Parizot C, Debre P, Vieillard V. NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. PLoS ONE. 2010;5:e11966 pubmed publisher
product information
master code :
MAB1847
SKU :
MAB1847
product name :
Human KIR2DS4/CD158i Antibody
unit size :
500 ug (also 25 ug)
description :
The Human KIR2DS4/CD158i Antibody from R&D Systems is a mouse monoclonal antibody to KIR2DS4/CD158i. This antibody reacts with human,mouse. The Human KIR2DS4/CD158i Antibody has been validated for the following applications: CyTOF-reported,Flow Cytometry,Functional Assay,Western Blot,CyTOF-ready.
target :
KIR2DS4/CD158i
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
179315
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human KIR2DS4, Accession # P43632
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects KIR2DS4/CD158i in Western blots. In flow cytometry, this antibody stains cells transfected with KIR2DS4/CD158i. Does not stain cells transfected with KIR2DL1, 2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 3DL1, 3DL2, or 3DS1.
gene symbol :
KIR2DS4
accessionNumbers :
P43632
applications :
CyTOF-reported,Flow Cytometry,Functional Assay,Western Blot,CyTOF-ready
USD :
559 USD
alt names :
CD158 antigen-like family member I, CD158I, CD158i antigen, cl-39, killer cell immunoglobulin-like receptor 2DS4, killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail4,nkat8, killer inhibitory receptor 4-1-2, KIR antigen 2DS4, KKA3KIR1D, MGC120019, MGC125315, MGC125317, MHC class I NK cell receptor, natural killer cell inhibitory receptor, Natural killer-associated transcript 8, NKAT-8, NKAT8KIR412, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.