product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human KIR2DL1/KIR2DS5 Antibody
catalog :
MAB1844-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
143211
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 16
Reference
David G, Willem C, Legrand N, Djaoud Z, M xe9 rieau P, Walencik A, et al. Deciphering the biology of KIR2DL3+ T lymphocytes that are associated to relapse in haploidentical HSCT. Sci Rep. 2021;11:15782 pubmed publisher
Dubreuil L, Maniangou B, Chevallier P, Quéméner A, Legrand N, Bene M, et al. Centromeric KIR AA Individuals Harbor Particular KIR Alleles Conferring Beneficial NK Cell Features with Implications in Haplo-Identical Hematopoietic Stem Cell Transplantation. Cancers (Basel). 2020;12: pubmed publisher
Gimeno L, Serrano López E, Campillo J, Cánovas Zapata M, Acuña O, Garcia Cozar F, et al. KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling. Cancers (Basel). 2020;12: pubmed publisher
Koenig A, Chen C, Marcais A, Barba T, Mathias V, Sicard A, et al. Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants. Nat Commun. 2019;10:5350 pubmed publisher
Kristensen A, Kent S, Parsons M. Contribution of NK Cell Education to both Direct and Anti-HIV-1 Antibody-Dependent NK Cell Functions. J Virol. 2018;92: pubmed publisher
Nguyen S, Achour A, Souchet L, Vigouroux S, Chevallier P, Furst S, et al. Clinical impact of NK-cell reconstitution after reduced intensity conditioned unrelated cord blood transplantation in patients with acute myeloid leukemia: analysis of a prospective phase II multicenter trial on behalf of the Société Française de Gre. Bone Marrow Transplant. 2017;52:1428-1435 pubmed publisher
Malnati M, Ugolotti E, Monti M, Battista D, Vanni I, Bordo D, et al. Activating Killer Immunoglobulin Receptors and HLA-C: a successful combination providing HIV-1 control. Sci Rep. 2017;7:42470 pubmed publisher
Riou R, Bressollette Bodin C, Boutoille D, Gagne K, Rodallec A, Lefebvre M, et al. Severe Symptomatic Primary Human Cytomegalovirus Infection despite Effective Innate and Adaptive Immune Responses. J Virol. 2017;91: pubmed publisher
Kennedy P, Chazara O, Gardner L, Ivarsson M, Farrell L, Xiong S, et al. Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy. J Immunol. 2016;197:4292-4300 pubmed
Horowitz A, Guethlein L, Nemat Gorgani N, Norman P, Cooley S, Miller J, et al. Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation. J Immunol. 2015;195:4524-36 pubmed publisher
Enqvist M, Ask E, Forslund E, Carlsten M, Abrahamsen G, Béziat V, et al. Coordinated expression of DNAM-1 and LFA-1 in educated NK cells. J Immunol. 2015;194:4518-27 pubmed publisher
Huijskens M, Walczak M, Sarkar S, Atrafi F, Senden Gijsbers B, Tilanus M, et al. Ascorbic acid promotes proliferation of natural killer cell populations in culture systems applicable for natural killer cell therapy. Cytotherapy. 2015;17:613-20 pubmed publisher
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol. 2013;43:480-7 pubmed publisher
Denman C, Senyukov V, Somanchi S, Phatarpekar P, Kopp L, Johnson J, et al. Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells. PLoS ONE. 2012;7:e30264 pubmed publisher
Beziat V, Descours B, Parizot C, Debre P, Vieillard V. NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. PLoS ONE. 2010;5:e11966 pubmed publisher
Bari R, Bell T, Leung W, Vong Q, Chan W, Das Gupta N, et al. Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine 245. Blood. 2009;114:5182-90 pubmed publisher
product information
master code :
MAB1844
SKU :
MAB1844-100
product name :
Human KIR2DL1/KIR2DS5 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human KIR2DL1/KIR2DS5 Antibody from R&D Systems is a mouse monoclonal antibody to KIR2DL1/KIR2DS5. This antibody reacts with human. The Human KIR2DL1/KIR2DS5 Antibody has been validated for the following applications: CyTof,Flow Cytometry,Immunocytochemistry,CyTOF-reported.
target :
KIR2DL1/KIR2DS5
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
143211
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human KIR2DL1/KIR2DS5, Accession # P43626
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human KIR2DL1/KIR2DS5 on transfected cells. It does not stain cells transfected with KIR2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
gene symbol :
KIR2DL1
top caption :
Detection of KIR2DL1/KIR2DS5 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
P43626
applications :
CyTof,Flow Cytometry,Immunocytochemistry,CyTOF-reported
USD :
459 USD
alt names :
CD158a, CD158g, NKAT9
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.