This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human E-Cadherin Antibody
catalog :
MAB1838
quantity :
100 ug (also 25 ug, 500 ug)
price :
359 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
180215
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig s4a
Vanneste M, Huang Q, Li M, Moose D, Zhao L, STAMNES M, et al. High content screening identifies monensin as an EMT-selective cytotoxic compound. Sci Rep. 2019;9:1200 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 2a
  • western blot; human; fig 2b
Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, et al. Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer. Biochem Pharmacol. 2016;118:18-30 pubmed publisher
An S, Raju I, Surenkhuu B, Kwon J, Gulati S, Karaman M, et al. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Ocul Surf. 2019;: pubmed publisher
Shibata S, Hayashi R, Okubo T, Kudo Y, Katayama T, Ishikawa Y, et al. Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages. Cell Rep. 2018;25:1668-1679.e5 pubmed publisher
Zeng S, Zhu B, Zeng J, Wu W, Jiang C. Zeylenone represses the progress of human prostate cancer by downregulating the Wnt/β‑catenin pathway. Mol Med Rep. 2018;18:5572-5578 pubmed publisher
Roux L, Petit I, Domart R, Concordet J, Qu J, Zhou H, et al. Modeling of Aniridia-Related Keratopathy by CRISPR/Cas9 Genome Editing of Human Limbal Epithelial Cells and Rescue by Recombinant PAX6 Protein. Stem Cells. 2018;36:1421-1429 pubmed publisher
Panzarini E, Inguscio V, Fimia G, Dini L. Rose Bengal acetate photodynamic therapy (RBAc-PDT) induces exposure and release of Damage-Associated Molecular Patterns (DAMPs) in human HeLa cells. PLoS ONE. 2014;9:e105778 pubmed publisher
Hashimoto T, Soeno Y, Maeda G, Taya Y, Aoba T, Nasu M, et al. Progression of oral squamous cell carcinoma accompanied with reduced E-cadherin expression but not cadherin switch. PLoS ONE. 2012;7:e47899 pubmed publisher
Maupin K, Sinha A, Eugster E, Miller J, Ross J, Paulino V, et al. Glycogene expression alterations associated with pancreatic cancer epithelial-mesenchymal transition in complementary model systems. PLoS ONE. 2010;5:e13002 pubmed publisher
Franciszkiewicz K, Le Floc h A, Jalil A, Vigant F, Robert T, Vergnon I, et al. Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention. Cancer Res. 2009;69:6249-55 pubmed publisher
Wanami L, Chen H, Peiro S, Garcia de Herreros A, Bachelder R. Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression. Exp Cell Res. 2008;314:2448-53 pubmed publisher
Miyazawa J, Mitoro A, Kawashiri S, Chada K, Imai K. Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity. Cancer Res. 2004;64:2024-9 pubmed
product information
brand :
R&D Systems
master code :
MAB1838
SKU :
MAB1838-100
product name :
Human E-Cadherin Antibody
description :
The Human E-Cadherin Antibody from R&D Systems is a mouse monoclonal antibody to E-Cadherin. This antibody reacts with human. The Human E-Cadherin Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry.
target :
E-Cadherin
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
180215
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human E-Cadherin, Asp155-Ile707, Accession # P12830
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human E-Cadherin in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Cadherin-8, rhCadherin-17, recombinant mouse E-Cadherin, rhN-Cadherin, rhP-Cadherin, or rhVE-Cadherin is observed.
gene symbol :
CDH1
catalog number base :
MAB1838
accessionNumbers :
P12830
applications :
Western Blot, Simple Western, Immunohistochemistry
2020 USD :
339
2021 USD :
359 USD
alt names :
Arc-1, CAD1, cadherin 1, E-cadherin (epithelial), cadherin 1, type 1, E-cadherin (epithelial), cadherin-1, calcium-dependent adhesion protein, epithelial, CAM 120/80, CD324, CD324 antigen, CDH1, CDHE, cell-CAM 120/80, Cell-CAM120/80, ECAD, E-cadherin, ECadherin, Epithelial cadherin, LCAM, L-CAM, UVOE-Cadherin, uvomorulin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.