Mouse EBI3 Antibody | R&D Systems MAB18341 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse EBI3 Antibody

catalog :

MAB18341

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

355022

reactivity :

human, mouse

application :

western blot, ELISA, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Dwyer L, Maheshwari S, Levy E, Poznansky M, Whalen M, S xee rbulescu R. B cell treatment promotes a neuroprotective microenvironment after traumatic brain injury through reciprocal immunomodulation with infiltrating peripheral myeloid cells. J Neuroinflammation. 2023;20:133 pubmed publisher
Luo Z, Sol xe4 ng C, Larsson R, Singh K. Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes. Int J Mol Sci. 2022;23: pubmed publisher
Lee S, Moon S, Moon Y, Seo H, Ryu J, Lee A, et al. A novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthritis via reciprocal regulation of Th17 and Treg cells. Cell Mol Immunol. 2022;19:79-91 pubmed publisher
Ruiz Torres S, Bourn J, Benight N, Hunt B, Lester C, Waltz S. Macrophage-mediated RON signaling supports breast cancer growth and progression through modulation of IL-35. Oncogene. 2022;41:321-333 pubmed publisher
Min B, Kim D, Feige M. IL-30† (IL-27A): a familiar stranger in immunity, inflammation, and cancer. Exp Mol Med. 2021;53:823-834 pubmed publisher
Jensen H, Chen S, Folkersen L, Nolan G, Lanier L. EBI3 regulates the NK cell response to mouse cytomegalovirus infection. Proc Natl Acad Sci U S A. 2017;114:1625-1630 pubmed publisher
Kochetkova I, Thornburg T, Callis G, Holderness K, Maddaloni M, Pascual D. Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27. J Immunol. 2014;192:804-16 pubmed publisher
Kochetkova I, Golden S, Holderness K, Callis G, Pascual D. IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10. J Immunol. 2010;184:7144-53 pubmed publisher
Ilarregui J, Croci D, Bianco G, Toscano M, Salatino M, Vermeulen M, et al. Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat Immunol. 2009;10:981-91 pubmed publisher

product information

master code :

MAB18341

SKU :

MAB18341

product name :

Mouse EBI3 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse EBI3 Antibody from R&D Systems is a rat monoclonal antibody to EBI3. This antibody reacts with human,mouse. The Mouse EBI3 Antibody has been validated for the following applications: ELISA Capture,ELISA Development,Immunodepletion,Flow Cytometry,Western Blot.

target :

EBI3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

355022

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse IL-27 heterodimer, Tyr19-Pro228 (EBI3) & Phe29-Ser234 (p28), Accession # O35228 (EBI3) & Q8K3I6 (p28)

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects mouse IL-27/IL-35 EBI3 Subunit in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human IL-27/IL-35 EBI3 subunit.

gene symbol :

EBI3

top caption :

Detection of Mouse IL-27/IL-35 EBI3 Subunit antibody by Western Blot.

accessionNumbers :

O35228 (EBI3) Q8K3I6 (p28)

applications :

ELISA Capture,ELISA Development,Immunodepletion,Flow Cytometry,Western Blot

USD :

439 USD

alt names :

cytokine receptor, EBI-3, EBV-induced gene 3 protein, Epstein-Barr virus induced 3, Epstein-Barr virus induced gene 3, Epstein-Barr virus-induced gene 3 protein, IL-27 beta, IL-27 subunit beta, IL27B, IL-27B, IL35 EBI3, IL-35 EBI3, interleukin-27 subunit beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage