Human TREM2 Antibody | R&D Systems MAB1828 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TREM2 Antibody

catalog :

MAB1828

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

263602

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Quan D, Cooper M, Potter J, Roberts M, Cheng H, Jarvis G. TREM-2 binds to lipooligosaccharides of Neisseria gonorrhoeae and is expressed on reproductive tract epithelial cells. Mucosal Immunol. 2008;1:229-38 pubmed publisher
western blot; human	Ochi S, Shinohara M, Sato K, Gober H, Koga T, Kodama T, et al. Pathological role of osteoclast costimulation in arthritis-induced bone loss. Proc Natl Acad Sci U S A. 2007;104:11394-9 pubmed
	Subramani M, Lambrecht B, Ahmad I. Human microglia-derived proinflammatory cytokines facilitate human retinal ganglion cell development and regeneration. Stem Cell Reports. 2024;19:1092-1106 pubmed publisher
	Filipello F, You S, Mirfakhar F, Mahali S, Bollman B, Acquarone M, et al. Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation. Acta Neuropathol. 2023;145:749-772 pubmed publisher
	Akhter R, Shao Y, Formica S, Khrestian M, Bekris L. TREM2 alters the phagocytic, apoptotic and inflammatory response to Aβ42 in HMC3 cells. Mol Immunol. 2021;131:171-179 pubmed publisher
	Weber G, Koenig K, Khrestian M, Shao Y, Tuason E, Gramm M, et al. An Altered Relationship between Soluble TREM2 and Inflammatory Markers in Young Adults with Down Syndrome: A Preliminary Report. J Immunol. 2020;204:1111-1118 pubmed publisher
	Cooper Knock J, Green C, Altschuler G, Wei W, Bury J, Heath P, et al. A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis. Acta Neuropathol Commun. 2017;5:23 pubmed publisher

product information

master code :

MAB1828

SKU :

MAB1828

product name :

Human TREM2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human TREM2 Antibody from R&D Systems is a mouse monoclonal antibody to TREM2. This antibody reacts with human. The Human TREM2 Antibody has been validated for the following applications: Immunocytochemistry,ELISA Development (Capture),Flow Cytometry,Western Blot.

target :

TREM2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

263602

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TREM2, His19-Ser174, Accession # Q9NZC2

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human TREM2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human TREM1, recombinant mouse (rm) TREM2b, or rmTREM3 is observed.

gene symbol :

TREM2

accessionNumbers :

Q9NZC2

applications :

Immunocytochemistry,ELISA Development (Capture),Flow Cytometry,Western Blot

USD :

499 USD

alt names :

PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c, TREM-2triggering receptor expressed on myeloid cells 2a, Triggering receptor expressed on monocytes 2, triggering receptor expressed on myeloid cells 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage