product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Klotho Antibody
catalog :
MAB1819
quantity :
500 ug (also 25 ug)
price :
589 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
236214
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
more info or order :
citations: 6
Reference
Iijima H, Gilmer G, Wang K, Bean A, He Y, Lin H, et al. Age-related matrix stiffening epigenetically regulates α-Klotho expression and compromises chondrocyte integrity. Nat Commun. 2023;14:18 pubmed publisher
Sahu A, Clemens Z, Shinde S, Sivakumar S, Pius A, Bhatia A, et al. Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles. Nat Aging. 2021;1:1148-1161 pubmed publisher
Zhang J, Cao K, Pastor J, Li L, Moe O, Hsia C. Alpha-Klotho, a critical protein for lung health, is not expressed in normal lung. FASEB Bioadv. 2019;1:675-687 pubmed publisher
Welc S, Wehling Henricks M, Kuro O M, Thomas K, Tidball J. Modulation of Klotho expression in injured muscle perturbs Wnt signalling and influences the rate of muscle growth. Exp Physiol. 2020;105:132-147 pubmed publisher
Cao F, Li Z, Ding W, Yan L, Zhao Q. LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation. Mol Med. 2019;25:7 pubmed publisher
Polanska U, Edwards E, Fernig D, Kinnunen T. The cooperation of FGF receptor and Klotho is involved in excretory canal development and regulation of metabolic homeostasis in Caenorhabditis elegans. J Biol Chem. 2011;286:5657-66 pubmed publisher
product information
master code :
MAB1819
SKU :
MAB1819
product name :
Mouse Klotho Antibody
unit size :
500 ug (also 25 ug)
description :
The Mouse Klotho Antibody from R&D Systems is a rat monoclonal antibody to Klotho. This antibody reacts with human,mouse,nematode - caenorhabditis elegans. The Mouse Klotho Antibody has been validated for the following applications: Immunohistochemistry,Immunoprecipitation,Western Blot,ELISA.
target :
Klotho
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
236214
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Klotho
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse,Nematode - Caenorhabditis elegans
specificity :
Detects mouse Klotho (aa 23-550 and aa 35-982) in direct ELISAs and Western blots. Does not cross-react with recombinant human Klotho or recombinant mouse Klotho B.
gene symbol :
KL
top caption :
Mouse Klotho Antibody in ELISA Standard Curve.
applications :
Immunoprecipitation,Western Blot,Immunohistochemistry,ELISA
USD :
589 USD
alt names :
EC 3.2.1, EC 3.2.1.31, KL, klotho
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.