Human CCR5 Antibody | R&D Systems MAB1801-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR5 Antibody

catalog :

MAB1801-100

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CTC8

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Weichseldorfer M, Tagaya Y, Reitz M, DeVico A, Latinovic O. Identifying CCR5 coreceptor populations permissive for HIV-1 entry and productive infection: implications for in vivo studies. J Transl Med. 2022;20:39 pubmed publisher
Song S, Manook M, Kwun J, Jackson A, Knechtle S, Kelsoe G. A cell-based multiplex immunoassay platform using fluorescent protein-barcoded reporter cell lines. Commun Biol. 2021;4:1338 pubmed publisher
Chain B, Arnold J, Akthar S, Brandt M, Davis D, Noursadeghi M, et al. A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody. PLoS ONE. 2015;10:e0128381 pubmed publisher
Fox J, Kasprowicz R, Hartley O, Signoret N. CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells. J Leukoc Biol. 2015;98:59-71 pubmed publisher
Nakano Y, Monde K, Terasawa H, Yuan Y, Yusa K, Harada S, et al. Preferential recognition of monomeric CCR5 expressed in cultured cells by the HIV-1 envelope glycoprotein gp120 for the entry of R5 HIV-1. Virology. 2014;452-453:117-24 pubmed publisher
Swaminathan G, Rossi F, Sierra L, Gupta A, Navas Martin S, MARTIN GARCIA J. A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages. PLoS Pathog. 2012;8:e1002937 pubmed publisher
Tilton J, Wilen C, Didigu C, Sinha R, Harrison J, Agrawal Gamse C, et al. A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5. J Virol. 2010;84:10863-76 pubmed publisher
Ottonello L, Montecucco F, Bertolotto M, Arduino N, Mancini M, Corcione A, et al. CCL3 (MIP-1alpha) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2. Cell Signal. 2005;17:355-63 pubmed

product information

master code :

MAB1801

SKU :

MAB1801-100

product name :

Human CCR5 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human CCR5 Antibody from R&D Systems is a mouse monoclonal antibody to CCR5. This antibody reacts with human. The Human CCR5 Antibody has been validated for the following applications: Functional Assay,ELISA Development,Flow Cytometry,Western Blot,Immunocytochemistry,Immunoprecipitation.

target :

CCR5

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

CTC8

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

CHO Chinese hamster ovary cell line transfected with human CCR5

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CCR5 in direct ELISAs and Western blots. For additional information regarding epitope specificity for this antibody and other R D Systems anti-human CCR5 antibodies, see reference 1 below.

gene symbol :

CCR5

applications :

ELISA Development,Flow Cytometry,Western Blot,Immunocytochemistry,Immunoprecipitation

USD :

479 USD

alt names :

C-C CKR-5, C-C motif chemokine receptor 5 A159A, CCCKR5, CC-CKR-5FLJ78003, CCR5, CCR-5, CD195, CD195 antigen, chemokine (C-C motif) receptor 5, chemokine receptor CCR5, chemr13, CKR5, CKR-5, HIV-1 fusion coreceptor, IDDM22CMKBR5C-C chemokine receptor type 5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage