product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat HSP60 Antibody
catalog :
MAB1800
quantity :
100 ug (also 25 ug)
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
264233
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 7
Reference
Stein K, Moon S, Nguyen A, SIKES H. Kinetic modeling of H2O2 dynamics in the mitochondria of HeLa cells. PLoS Comput Biol. 2020;16:e1008202 pubmed publisher
Choi S, López González R, Krishnan G, Phillips H, Li A, Seeley W, et al. C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo. Nat Neurosci. 2019;22:851-862 pubmed publisher
Wettmarshausen J, Goh V, Huang K, Arduino D, Tripathi U, Leimpek A, et al. MICU1 Confers Protection from MCU-Dependent Manganese Toxicity. Cell Rep. 2018;25:1425-1435.e7 pubmed publisher
Yao Y, Wu J, Gu T, Cheng Y, Li G. Comparative analysis of the interaction of HSPs in dendritic cells, macrophages, RGM-1 cells infected by Helicobacter pylori. Am J Transl Res. 2016;8:4184-4194 pubmed
Noelker C, Morel L, Osterloh A, Alvarez Fischer D, Lescot T, Breloer M, et al. Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease. J Neuroinflammation. 2014;11:86 pubmed publisher
Ji J, Tyurina Y, Tang M, Feng W, Stolz D, Clark R, et al. Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids. J Neurotrauma. 2012;29:776-88 pubmed publisher
Gotoh T, Oyadomari S, Mori K, Mori M. Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP. J Biol Chem. 2002;277:12343-50 pubmed
product information
master code :
MAB1800
SKU :
MAB1800
product name :
Human/Mouse/Rat HSP60 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat HSP60 Antibody from R&D Systems is a mouse monoclonal antibody to HSP60. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat HSP60 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry.
target :
HSP60
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
264233
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human HSP60, Met1-Phe573, Accession # P10809
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human, mouse and rat HSP60.
gene symbol :
HSPD1
top caption :
Detection of Human/Mouse/Rat HSP60 antibody by Western Blot.
accessionNumbers :
P10809
applications :
Western Blot,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry
USD :
449 USD
alt names :
60 kDa chaperonin, Chaperonin 60, CPN60, GROEL, heat shock 60kD protein 1 (chaperonin), heat shock 60kDa protein 1 (chaperonin), Heat shock protein 60, heat shock protein 65, HLD4, Hsp60, HSP-60, HSP60SPG13, HSP65, HSPD1, HuCHA60, Mitochondrial matrix protein P1,60 kDa heat shock protein, mitochondrial, P60 lymphocyte protein, short heat shock protein 60 Hsp60s1, spastic paraplegia 13 (autosomal dominant), SPG13
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.