Human/Mouse/Rat STAT3 Antibody | R&D Systems MAB1799 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat STAT3 Antibody

catalog :

MAB1799

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

232209

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 24

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:100; loading ...; fig 2j	Castillo P, Aisagbonhi O, Saenz C, ElShamy W. Novel insights linking BRCA1-IRIS role in mammary gland development to formation of aggressive PABCs: the case for longer breastfeeding. Am J Cancer Res. 2022;12:396-426 pubmed
	Chakraborty R, Khodlan P, Tay A, Liu F. STAT3 interactome predicts presence of proteins that regulate immune system in oral squamous cell carcinoma. J Oral Biosci. 2024;66:67-73 pubmed publisher
	Kim J, Ham J, Kang H, Bae Y, Kim T, Kim H. JAK3 inhibitor suppresses multipotent ILC2s and attenuates steroid-resistant asthma. Sci Adv. 2023;9:eadi3770 pubmed publisher
	Li S, Pritchard D, Yu L. Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells. Cell Death Dis. 2023;14:268 pubmed publisher
	Iwasa K, Yamagishi A, Yamamoto S, Haruta C, Maruyama K, Yoshikawa K. GPR137 Inhibits Cell Proliferation and Promotes Neuronal Differentiation in the Neuro2a Cells. Neurochem Res. 2023;48:996-1008 pubmed publisher
	Caso F, Saviano A, Tasso M, Raucci F, Marigliano N, Passavanti S, et al. Analysis of rheumatoid- vs psoriatic arthritis synovial fluid reveals differential macrophage (CCR2) and T helper subsets (STAT3/4 and FOXP3) activation. Autoimmun Rev. 2022;21:103207 pubmed publisher
	Al Rawashde F, Al Wajeeh A, Vishkaei M, Saad H, Johan M, Taib W, et al. Thymoquinone Inhibits JAK/STAT and PI3K/Akt/ mTOR Signaling Pathways in MV4-11 and K562 Myeloid Leukemia Cells. Pharmaceuticals (Basel). 2022;15: pubmed publisher
	Kershaw J, Elzey B, Guo X, Kim K. Piceatannol, a Dietary Polyphenol, Alleviates Adipose Tissue Loss in Pre-Clinical Model of Cancer-Associated Cachexia via Lipolysis Inhibition. Nutrients. 2022;14: pubmed publisher
	Harper J, Ribeiro S, Chan C, Aid M, Deléage C, Micci L, et al. Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy. J Clin Invest. 2022;: pubmed publisher
	Chakraborty R, Hu H, Darido C, Vickery K, Ranganathan S. ML218 HCl Is More Efficient Than Capsaicin in Inhibiting Bacterial Antigen-Induced Cal 27 Oral Cancer Cell Proliferation. Int J Mol Sci. 2021;22: pubmed publisher
	Chakraborty R, Vickery K, Darido C, Ranganathan S, Hu H. Bacterial Antigens Reduced the Inhibition Effect of Capsaicin on Cal 27 Oral Cancer Cell Proliferation. Int J Mol Sci. 2021;22: pubmed publisher
	Zhang H, Corredor A, Messina Pacheco J, Li Q, Zogopoulos G, Kaddour N, et al. REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway. Commun Biol. 2021;4:688 pubmed publisher
	Tang K, Lin C, Lin S, Wang J, Tsai S. Kurarinone Attenuates Collagen-Induced Arthritis in Mice by Inhibiting Th1/Th17 Cell Responses and Oxidative Stress. Int J Mol Sci. 2021;22: pubmed publisher
	Wu S, Yang W, Cheng C, Lin K, Sampurna B, Chan S, et al. Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling. Clin Transl Med. 2020;10:e252 pubmed publisher
	Chen X, Mao R, Su W, Yang X, Geng Q, Guo C, et al. Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPKα signaling in STK11 mutant lung cancer. Autophagy. 2020;16:659-671 pubmed publisher
	Ryan D, Paul B, Koziol J, ElShamy W. The pro- and anti-tumor roles of mesenchymal stem cells toward BRCA1-IRIS-overexpressing TNBC cells. Breast Cancer Res. 2019;21:53 pubmed publisher
	Zheng Y, Cui Y, Yang S, Wang Y, Qiu Y, Hu W. Opa interacting protein 5 promotes metastasis of nasopharyngeal carcinoma cells by promoting EMT via modulation of JAK2/STAT3 signal. Eur Rev Med Pharmacol Sci. 2019;23:613-621 pubmed publisher
	Frey Jakobs S, Hartberger J, Fliegauf M, Bossen C, Wehmeyer M, Neubauer J, et al. ZNF341 controls STAT3 expression and thereby immunocompetence. Sci Immunol. 2018;3: pubmed publisher
	Xu H, Zhou Y, Li W, Zhang B, Zhang H, Zhao S, et al. Tumor-derived mesenchymal-stem-cell-secreted IL-6 enhances resistance to cisplatin via the STAT3 pathway in breast cancer. Oncol Lett. 2018;15:9142-9150 pubmed publisher
	Yamada K, Huang Z, Raska M, Reily C, Anderson J, Suzuki H, et al. Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy. Kidney Int Rep. 2017;2:1194-1207 pubmed publisher
	Wang L, Zheng Q, Yuan Y, Li Y, Gong X. Effects of 17β-estradiol and 2-methoxyestradiol on the oxidative stress-hypoxia inducible factor-1 pathway in hypoxic pulmonary hypertensive rats. Exp Ther Med. 2017;13:2537-2543 pubmed publisher
	Zhao Z, Li J, Ye R, Wu X, Gao L, Niu B. Interleukin-6 as a potential molecular target in esophageal squamous cell carcinoma. Oncol Lett. 2016;11:925-932 pubmed
	Bruhn M, Townsend A, Khoon Lee C, Shivasami A, Price T, Wrin J, et al. Proangiogenic tumor proteins as potential predictive or prognostic biomarkers for bevacizumab therapy in metastatic colorectal cancer. Int J Cancer. 2014;135:731-41 pubmed publisher
	Kolliputi N, Waxman A. IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation. Am J Respir Cell Mol Biol. 2009;40:314-24 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB1799

SKU :

MAB1799

product name :

Human/Mouse/Rat STAT3 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat STAT3 Antibody from R&D Systems is a mouse monoclonal antibody to STAT3. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat STAT3 Antibody has been validated for the following applications: Western Blot,Co-Immunoprecipitation,Functional Assay,Immunoprecipitation,Intracellular Staining by Flow Cytometry,Immunocytochemistry,Knockout Validated.

target :

STAT3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

232209

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunoprecipitation 1-3 ug/500 ug cell lysate, Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells, Immunocytochemistry 3-25 ug/mL, Knockout Validated

host :

Mouse

immunogen :

E. coli -derived recombinant human STAT3, Met1-Asn175, Accession # P40763

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human, mouse, and rat STAT3 in Western blots.

gene symbol :

STAT3

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human STAT3 antibody by Western Blot.

accessionNumbers :

P40763

applications :

Immunoprecipitation,Intracellular Staining by Flow Cytometry,Immunocytochemistry,Knockout Validated,Co-Immunoprecipitation,Western Blot,Functional Assay

USD :

509 USD

alt names :

Acute-phase response factor, APRFMGC16063, DNA-binding protein APRF, FLJ20882, HIES, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase responsefactor)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage