Human LOX-1/OLR1 Antibody | R&D Systems MAB1798 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human LOX-1/OLR1 Antibody

catalog :

MAB1798

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

331212

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Huang L, Chambliss K, Gao X, Yuhanna I, Behling Kelly E, Bergaya S, et al. SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis. Nature. 2019;569:565-569 pubmed publisher
Tsukahara R, Haniu H, Matsuda Y, Tsukahara T. The AGP-PPARγ axis promotes oxidative stress and diabetic endothelial cell dysfunction. Mol Cell Endocrinol. 2018;473:100-113 pubmed publisher
Skarpengland T, Skjelland M, Kong X, Skagen K, Holm S, Otterdal K, et al. Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack. J Am Heart Assoc. 2018;7: pubmed publisher
Condamine T, Dominguez G, Youn J, Kossenkov A, Mony S, Alicea Torres K, et al. Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients. Sci Immunol. 2016;1: pubmed publisher
Fong O, Chan K, Leung K, Lam H, Cheung H, Leung T, et al. Expression profile of cord blood neutrophils and dysregulation of HSPA1A and OLR1 upon challenge by bacterial peptidoglycan. J Leukoc Biol. 2014;95:169-78 pubmed publisher
Nowicki M, Kosacka J, Serke H, Bluher M, Spanel Borowski K. Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome. J Neurosci Res. 2012;90:122-31 pubmed publisher
Zhang L, Liu Y, Lu X, Wu Y, Zhang C, Ji X, et al. Traditional Chinese medication Tongxinluo dose-dependently enhances stability of vulnerable plaques: a comparison with a high-dose simvastatin therapy. Am J Physiol Heart Circ Physiol. 2009;297:H2004-14 pubmed publisher
Vilser C, Hueller H, Nowicki M, Hmeidan F, Blumenauer V, Spanel Borowski K. The variable expression of lectin-like oxidized low-density lipoprotein receptor (LOX-1) and signs of autophagy and apoptosis in freshly harvested human granulosa cells depend on gonadotropin dose, age, and body weight. Fertil Steril. 2010;93:2706-15 pubmed publisher

product information

master code :

MAB1798

SKU :

MAB1798

product name :

Human LOX-1/OLR1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human LOX-1/OLR1 Antibody from R&D Systems is a mouse monoclonal antibody to LOX-1/OLR1. This antibody reacts with human,mouse,rabbit. The Human LOX-1/OLR1 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,Blockade of Receptor-ligand Interaction,CyTOF-ready.

target :

LOX-1/OLR1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

331212

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human LOX-1/OLR1, Ser61-Gln273, Accession # P78380

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rabbit

specificity :

Detects human LOX-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant mouse LOX-1.

gene symbol :

OLR1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of LOX-1/OLR1 antibody in THP-1 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

P78380

applications :

Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,Blockade of Receptor-ligand Interaction,CyTOF-ready

USD :

489 USD

alt names :

CLEC8A, CLEC8ASLOX1, C-type lectin domain family 8 member A, hLOX-1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, LOX1, LOX-1, LOX1ox LDL receptor 1, LOXIN, OLR1, oxidised low density lipoprotein (lectin-like) receptor 1, oxidized low density lipoprotein (lectin-like) receptor 1, oxidized low-density lipoprotein receptor 1, oxidized low-density lipoprotein receptor 1, soluble form, Ox-LDL receptor 1, SCARE1, scavenger receptor class E, member 1, SR-E1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage