Human CCR9 Antibody | R&D Systems MAB179-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR9 Antibody

catalog :

MAB179-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

112509

reactivity :

human, rhesus macaque

application :

immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 11

Reference
Syu G, Wang S, Ma G, Liu S, Pearce D, Prakash A, et al. Development and application of a high-content virion display human GPCR array. Nat Commun. 2019;10:1997 pubmed publisher
Hu Y, Ma A, Lin S, Yang Y, Hong G. Novel peptide screened from a phage display library antagonizes the activity of CC chemokine receptor 9. Oncol Lett. 2017;14:6471-6476 pubmed publisher
Robert R, Ang C, Sun G, Juglair L, Lim E, Mason L, et al. Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice. JCI Insight. 2017;2: pubmed publisher
Oswald C, Rappas M, Kean J, Doré A, Errey J, Bennett K, et al. Intracellular allosteric antagonism of the CCR9 receptor. Nature. 2016;540:462-465 pubmed publisher
Johnson Holiday C, Singh R, Johnson E, Singh S, Stockard C, Grizzle W, et al. CCL25 mediates migration, invasion and matrix metalloproteinase expression by breast cancer cells in a CCR9-dependent fashion. Int J Oncol. 2011;38:1279-85 pubmed publisher
Wang Y, Yu J, Luo X, Wang X, Li M, Wang L, et al. Abnormal regulation of chemokine TECK and its receptor CCR9 in the endometriotic milieu is involved in pathogenesis of endometriosis by way of enhancing invasiveness of endometrial stromal cells. Cell Mol Immunol. 2010;7:51-60 pubmed publisher
Minang J, Trivett M, Bolton D, Trubey C, Estes J, Li Y, et al. Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection. J Immunol. 2010;184:315-26 pubmed publisher
Bolton D, Minang J, Trivett M, Song K, Tuscher J, Li Y, et al. Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques. J Immunol. 2010;184:303-14 pubmed publisher
Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, et al. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J Immunol. 2007;179:4272-82 pubmed
Ni Z, Campbell J, Niehans G, Walcheck B. The monoclonal antibody CHO-131 identifies a subset of cutaneous lymphocyte-associated antigen T cells enriched in P-selectin-binding cells. J Immunol. 2006;177:4742-8 pubmed
Annels N, Willemze A, van der Velden V, Faaij C, van Wering E, Sie Go D, et al. Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL. Blood. 2004;103:2806-8 pubmed

product information

master code :

MAB179

SKU :

MAB179-100

product name :

Human CCR9 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CCR9 Antibody from R&D Systems is a mouse monoclonal antibody to CCR9. This antibody reacts with human,primate - macaca mulatta (rhesus macaque). The Human CCR9 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunocytochemistry,Immunohistochemistry,CyTOF-ready.

target :

CCR9

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

112509

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

BaF3 mouse pro-B cell line transfected with human CCR9, Met1-Leu369, Accession # P51686

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Specifically stains human CCR9 transfectants and MOLT-4 cells. It does not react with the parental BaF3 cells or human CCR7-transfected BaF3 cells.

gene symbol :

CCR9

top caption :

CCR9 antibody in MOLT-4 Human Cell Line by Immunocytochemistry (ICC).

accessionNumbers :

P51686

applications :

Flow Cytometry,Neutralization,Immunocytochemistry,Immunohistochemistry,CyTOF-ready

extended description :

Clone 112509 was used by HLDA to establish CD designation

USD :

489 USD

product details :

Clone 112509 was used by HLDA to establish CD designation

alt names :

C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR9, CCR-9, CD199, CDw199, CDw199 antigen, chemokine (C-C motif) receptor 9, G protein-coupled receptor 28, GPR28, GPR-9-6G-protein coupled receptor 28

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage