product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Serpin E1/PAI-1 Antibody
catalog :
MAB1786-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
242816
reactivity :
human
application :
western blot, ELISA, neutralization
more info or order :
citations: 9
Reference
Zhu Y, Prata L, Gerdes E, Netto J, Pirtskhalava T, Giorgadze N, et al. Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans. EBioMedicine. 2022;77:103912 pubmed publisher
Camell C, Yousefzadeh M, Zhu Y, Langhi Prata L, Huggins M, Pierson M, et al. Senolytics reduce coronavirus-related mortality in old mice. Science. 2021;: pubmed publisher
Aissa A, Islam A, Ariss M, Go C, Rader A, Conrardy R, et al. Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer. Nat Commun. 2021;12:1628 pubmed publisher
Shaashua L, Eckerling A, Israeli B, Yanovich G, Rosenne E, Fichman Horn S, et al. Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome. BMC Biol. 2020;18:163 pubmed publisher
Nossin Y, Farrell E, Koevoet W, Somoza R, Caplan A, Brachvogel B, et al. Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1. Front Bioeng Biotechnol. 2020;8:327 pubmed publisher
Wiley C, Liu S, Limbad C, Zawadzka A, Beck J, Demaria M, et al. SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Cell Rep. 2019;28:3329-3337.e5 pubmed publisher
Kowtharapu B, Murin R, Jünemann A, Stachs O. Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing. Int J Mol Sci. 2018;19: pubmed publisher
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed publisher
Huang M, Patel K, Taub D, Longo D, Goetzl E. Human CD4- 8- T cells are a distinctive immunoregulatory subset. FASEB J. 2010;24:2558-66 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB1786
SKU :
MAB1786-100
product name :
Human Serpin E1/PAI-1 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human Serpin E1/PAI-1 Antibody from R&D Systems is a mouse monoclonal antibody to Serpin E1/PAI-1. This antibody reacts with human. The Human Serpin E1/PAI-1 Antibody has been validated for the following applications: Neutralization,Cell Lysates,Luminex Development,Western Blot,Simple Western,ELISA Capture (Matched Antibody Pair).
target :
Serpin E1/PAI-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
242816
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 2.5 ug/mL, Neutralization 0.3 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Serpin E1/PAI-1, Met1-Pro402, Accession # P05121
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Serpin E1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Serpin A1, A3, A4, A8, C1, F1, F2, I1, I2, recombinant mouse Serpin D1 or E2 is observed.
gene symbol :
SERPINE1
top caption :
Detection of Human Serpin E1/PAI-1 antibody by Western Blot.
accessionNumbers :
P05121
applications :
Simple Western,ELISA Capture (Matched Antibody Pair),Cell Lysates,Luminex Development,Western Blot,Neutralization
USD :
459 USD
alt names :
Endothelial plasminogen activator inhibitor, Nexin, PAI1, PAI-1, PAI1PAI-1, PAISerpin E1, PLANH1, PLANH1plasminogen activator inhibitor 1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.