product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Integrin ▀1/CD29 Antibody
catalog :
MAB17781
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
P5D2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 35
Reference
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Hussain M, Austin Williams S, Wright T, Dhawan U, Pinto A, Cooper D, et al. β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte Homeostasis. Int J Mol Sci. 2024;25: pubmed publisher
Brooks S, Mittler S, Hamilton D. Contact Guidance of Connective Tissue Fibroblasts on Submicrometer Anisotropic Topographical Cues Is Dependent on Tissue of Origin, β1 Integrins, and Tensin-1 Recruitment. ACS Appl Mater Interfaces. 2023;15:19817-19832 pubmed publisher
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Li Q, Huang L. MiR-148a-3p Regulates the Invasion and Odontoblastic Differentiation of Human Dental Pulp Stem Cells via the Wnt1/β-Catenin Pathway. Int J Stem Cells. 2021;14:434-446 pubmed publisher
Myint P, Ito A, Appiah M, Obeng G, Darkwah S, Kawamoto E, et al. Irisin supports integrin-mediated cell adhesion of lymphocytes. Biochem Biophys Rep. 2021;26:100977 pubmed publisher
Kawamoto E, Nago N, Okamoto T, Gaowa A, Masui Ito A, Akama Y, et al. The Lectin-Like Domain of Thrombomodulin Inhibits β1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin. Biomedicines. 2021;9: pubmed publisher
Yuan S, Zhang C, Zhu Y, Wang B. Neohesperidin Ameliorates Steroid-Induced Osteonecrosis of the Femoral Head by Inhibiting the Histone Modification of lncRNA HOTAIR. Drug Des Devel Ther. 2020;14:5419-5430 pubmed publisher
Luthria G, Li R, Wang S, Prytyskach M, Kohler R, Lauffenburger D, et al. In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells. Nat Commun. 2020;11:3521 pubmed publisher
Davies S, Reynolds G, Wilkinson A, Li X, Rose R, Leekha M, et al. Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process. Cell Rep. 2019;29:1610-1620.e4 pubmed publisher
Rajan A, Persson B, Frängsmyr L, Olofsson A, Sandblad L, Heino J, et al. Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Sci Rep. 2018;8:10019 pubmed publisher
Luczynski M, Harrison P, Lima N, Krásný L, Paul A, Huang P. Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity. Biochem Biophys Res Commun. 2018;501:124-130 pubmed publisher
Ahmad S, Brown J, Campbell L, Koscielniak M, Oliver C, Wheelhouse N, et al. Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment. EBioMedicine. 2018;29:159-165 pubmed publisher
Lovitt C, Shelper T, Avery V. Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins. BMC Cancer. 2018;18:41 pubmed publisher
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Storm R, Persson B, Skalman L, Frängsmyr L, Lindström M, Rankin G, et al. Human Adenovirus Type 37 Uses αVβ1 and α3β1 Integrins for Infection of Human Corneal Cells. J Virol. 2017;91: pubmed publisher
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product information
brand :
R&D Systems
master code :
MAB17781
SKU :
MAB17781
product name :
Human Integrin ▀1/CD29 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Integrin ß1/CD29 Antibody from R&D Systems is a mouse monoclonal antibody to Integrin beta 1/CD29. This antibody reacts with human,mouse,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque),primate - papio cynocephalus (yellow baboon). The Human Integrin ß1/CD29 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Bioassay,Neutralization,Flow Cytometery,Blocking,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Frozen,Immunofluorescence,Immunocytochemistry,Blockade of Receptor-ligand Interaction,CyTOF-ready,Knockout Validated.
target :
Integrin beta 1/CD29
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
P5D2
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Flow Cytometry 0.25 ug/10^6 cells, Immunoprecipitation, Blockade of Receptor-ligand Interaction, Immunocytochemistry 8-25 ug/mL, CyTOF-ready, Knockout Validated
host :
Mouse
immunogen :
Human skin keratinocytes
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque),Primate - Papio cynocephalus (Yellow Baboon)
specificity :
Detects human Integrin ▀1/CD29.
gene symbol :
ITGB1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Integrin ss1/CD29 antibody in Human PBMCs antibody by Flow Cytometry.
applications :
Immunoprecipitation,Blockade of Receptor-ligand Interaction,CyTOF-ready,Knockout Validated,Bioassay,Blocking,Flow Cytometery,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization,Immunofluorescence,Immunocytochemistry
USD :
489 USD
alt names :
CD29, CD29 antigen, Fibronectin receptor subunit beta, FNRBVLAB, GPIIA, integrin beta-1, integrin VLA-4 beta subunit, integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includesMDF2, MSK12), ITGB1, MDF2, MSK12, very late activation protein, beta polypeptide, VLA-4 subunit beta, VLA-BETA
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.