product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Rae-1 Pan Specific Antibody
catalog :
MAB17582-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
186107
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 24
Reference
Gund R, Christiano A. Impaired autophagy promotes hair loss in the C3H/HeJ mouse model of alopecia areata. Autophagy. 2023;19:296-305 pubmed publisher
Park J, Kim H, Kim C, Kim H, Jung Y, Lee H, et al. Tumor hypoxia represses γδ T cell-mediated antitumor immunity against brain tumors. Nat Immunol. 2021;22:336-346 pubmed publisher
Prinz D, Klein K, List J, Knab V, Menzl I, Leidenfrost N, et al. Loss of NKG2D in murine NK cells leads to increased perforin production upon long-term stimulation with IL-2. Eur J Immunol. 2020;50:880-890 pubmed publisher
D Alessandro G, Antonangeli F, Marrocco F, Porzia A, Lauro C, Santoni A, et al. Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice. Eur J Immunol. 2020;50:705-711 pubmed publisher
Dai K, Huang Y, Chen Z, Sun X, Yang L, Jiang Y. Kbtbd2 inhibits the cytotoxic activity of immortalized NK cells through down-regulating mTOR signaling in a mouse hepatocellular carcinoma model. Eur J Immunol. 2018;48:683-695 pubmed publisher
Morvan M, Champsaur M, Reizis B, Lanier L. Chronic In Vivo Interaction of Dendritic Cells Expressing the Ligand Rae-1ε with NK Cells Impacts NKG2D Expression and Function. Immunohorizons. 2017;1:10-19 pubmed publisher
Greene T, Tokuyama M, Knudsen G, Kunz M, Lin J, Greninger A, et al. A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression. elife. 2016;5: pubmed publisher
Raju S, Kretzmer L, Koues O, Payton J, Oltz E, Cashen A, et al. NKG2D-NKG2D Ligand Interaction Inhibits the Outgrowth of Naturally Arising Low-Grade B Cell Lymphoma In Vivo. J Immunol. 2016;196:4805-13 pubmed publisher
Luci C, Bekri S, Bihl F, Pini J, Bourdely P, Nouhen K, et al. NKp46+ Innate Lymphoid Cells Dampen Vaginal CD8 T Cell Responses following Local Immunization with a Cholera Toxin-Based Vaccine. PLoS ONE. 2015;10:e0143224 pubmed publisher
Dupuis Maurin V, Brinza L, Baguet J, Plantamura E, Schicklin S, Chambion S, et al. Overexpression of the transcription factor Sp1 activates the OAS-RNAse L-RIG-I pathway. PLoS ONE. 2015;10:e0118551 pubmed publisher
Nielsen M, Dyring Andersen B, Schmidt J, Witherden D, Lovato P, Woetmann A, et al. NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity. J Invest Dermatol. 2015;135:1311-1319 pubmed publisher
Weinger J, Plaisted W, Maciejewski S, Lanier L, Walsh C, Lane T. Activating receptor NKG2D targets RAE-1-expressing allogeneic neural precursor cells in a viral model of multiple sclerosis. Stem Cells. 2014;32:2690-701 pubmed publisher
Tu M, Mahmoud A, Wight A, Mottashed A, Belanger S, Rahim M, et al. Ly49 family receptors are required for cancer immunosurveillance mediated by natural killer cells. Cancer Res. 2014;74:3684-94 pubmed publisher
Crosby E, Goldschmidt M, Wherry E, Scott P. Engagement of NKG2D on bystander memory CD8 T cells promotes increased immunopathology following Leishmania major infection. PLoS Pathog. 2014;10:e1003970 pubmed publisher
Paolino M, Choidas A, Wallner S, Pranjic B, Uribesalgo I, Loeser S, et al. The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature. 2014;507:508-12 pubmed publisher
Wang R, Natarajan K, Revilleza M, Boyd L, Zhi L, Zhao H, et al. Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1γ reveals a paradigm for MHC/MHC interaction in immune evasion. Proc Natl Acad Sci U S A. 2012;109:E3578-87 pubmed publisher
Jung H, Hsiung B, Pestal K, Procyk E, Raulet D. RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. J Exp Med. 2012;209:2409-22 pubmed publisher
Borchers M, Wesselkamper S, Curull V, Ramirez Sarmiento A, Sánchez Font A, Garcia Aymerich J, et al. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. J Clin Invest. 2009;119:636-49 pubmed publisher
Nice T, Coscoy L, Raulet D. Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress. J Exp Med. 2009;206:287-98 pubmed publisher
Unni A, Bondar T, Medzhitov R. Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance. Proc Natl Acad Sci U S A. 2008;105:1686-91 pubmed publisher
Vilarinho S, Ogasawara K, Nishimura S, Lanier L, Baron J. Blockade of NKG2D on NKT cells prevents hepatitis and the acute immune response to hepatitis B virus. Proc Natl Acad Sci U S A. 2007;104:18187-92 pubmed
Barber A, Zhang T, Demars L, Conejo Garcia J, Roby K, Sentman C. Chimeric NKG2D receptor-bearing T cells as immunotherapy for ovarian cancer. Cancer Res. 2007;67:5003-8 pubmed
Gourzi P, Leonova T, Papavasiliou F. A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus. Immunity. 2006;24:779-86 pubmed
Terme M, Borg C, Guilhot F, Masurier C, Flament C, Wagner E, et al. BCR/ABL promotes dendritic cell-mediated natural killer cell activation. Cancer Res. 2005;65:6409-17 pubmed
product information
brand :
R&D Systems
master code :
MAB17582
SKU :
MAB17582-100
product name :
Mouse Rae-1 Pan Specific Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Mouse Rae-1 Pan Specific Antibody from R&D Systems is a rat monoclonal antibody to Rae-1. This antibody reacts with mouse. The Mouse Rae-1 Pan Specific Antibody has been validated for the following applications: Flow Cytometry,Surface Plasmon Resonance,Western Blot,Immunocytochemistry,CyTOF-ready.
target :
Rae-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
186107
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Flow Cytometry 0.25 ug/10^6 cells, CyTOF-ready
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Rae-1 delta , Leu29-Ser227, Accession # Q9JI58
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse Rae-1. It recognizes Rae-1 alpha , ▀, delta , gamma and epsilon .
gene symbol :
Raet1a
top caption :
Detection of Rae-1 antibody in RAW 264.7 Mouse Cell Line antibody by Flow Cytometry.
accessionNumbers :
Q9JI58
applications :
CyTOF-ready,Flow Cytometry,Western Blot,Immunocytochemistry
USD :
479 USD
alt names :
dJ481F12.3;dJ800J21.1;Gle2;MIG14;Mnrp41;mRNA export factor RAE1;MRNP41;RAE1, Rae1, Rae1 alpha, Rae1 beta, Rae1 delta, Rae1 epsilon, Rae1 gamma
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.