Human Lipocalin-2/NGAL Antibody | R&D Systems MAB1757-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Lipocalin-2/NGAL Antibody

catalog :

MAB1757-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

220310

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 21

Reference
Cheng M, Zheng Y, Fan Y, Yan P, Zhao W. The contribution of IL-17A-dependent low LCN2 levels to Helicobacter pylori infection: Insights from clinical and experimental studies. Int Immunopharmacol. 2023;124:110960 pubmed publisher
Lunardi F, Abbrescia D, Vedovelli L, Pezzuto F, Fortarezza F, Comacchio G, et al. Molecular Profiling of Tissue Samples with Chronic Rejection from Patients with Chronic Lung Allograft Dysfunction: A Pilot Study in Cystic Fibrosis Patients. Biomolecules. 2023;13: pubmed publisher
Yao F, Deng Y, Zhao Y, Mei Y, Zhang Y, Liu X, et al. A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis. Nat Commun. 2021;12:7333 pubmed publisher
Villodre E, Hu X, Larson R, Finetti P, Gomez K, Balema W, et al. Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion. Mol Oncol. 2021;: pubmed publisher
Espín R, Baiges A, Blommaert E, Herranz C, Roman A, Saez B, et al. Heterogeneity and Cancer-Related Features in Lymphangioleiomyomatosis Cells and Tissue. Mol Cancer Res. 2021;19:1840-1853 pubmed publisher
Zhang I, Lépine P, Han C, Lacalle Aurioles M, Chen C, Haag R, et al. Nanotherapeutic Modulation of Human Neural Cells and Glioblastoma in Organoids and Monocultures. Cells. 2020;9: pubmed publisher
Klinkhammer B, Djudjaj S, Kunter U, Palsson R, Edvardsson V, Wiech T, et al. Cellular and Molecular Mechanisms of Kidney Injury in 2,8-Dihydroxyadenine Nephropathy. J Am Soc Nephrol. 2020;31:799-816 pubmed publisher
Rehwald C, Schnetz M, Urbschat A, Mertens C, Meier J, Bauer R, et al. The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma. Br J Cancer. 2020;122:421-433 pubmed publisher
An S, Raju I, Surenkhuu B, Kwon J, Gulati S, Karaman M, et al. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Ocul Surf. 2019;: pubmed publisher
Krishnan V, BOOKER D, Cunningham G, Jadapalli J, Kain V, Pullen A, et al. Pretreatment of carprofen impaired initiation of inflammatory- and overlapping resolution response and promoted cardiorenal syndrome in heart failure. Life Sci. 2019;218:224-232 pubmed publisher
Ozturk O, Ustebay S, Eroglu H, Gunay M, Adali Y, Donmez İ, et al. An experimental study of ascorbic acid effects in acute renal failure under general anesthesia. Acta Cir Bras. 2017;32:853-861 pubmed publisher
Okuda M, Inoue J, Fujiwara N, Kawano T, Inazawa J. Subcloning and characterization of highly metastatic cells derived from human esophageal squamous cell carcinoma KYSE150 cells by in vivo selection. Oncotarget. 2017;8:34670-34677 pubmed publisher
Dekens D, Naudé P, Engelborghs S, Vermeiren Y, Van Dam D, Oude Voshaar R, et al. Neutrophil Gelatinase-Associated Lipocalin and its Receptors in Alzheimer's Disease (AD) Brain Regions: Differential Findings in AD with and without Depression. J Alzheimers Dis. 2017;55:763-776 pubmed
Oren B, Urosevic J, Mertens C, Mora J, Guiu M, Gomis R, et al. Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis. J Pathol. 2016;239:274-85 pubmed publisher
Bi F, Huang C, Tong J, Qiu G, Huang B, Wu Q, et al. Reactive astrocytes secrete lcn2 to promote neuron death. Proc Natl Acad Sci U S A. 2013;110:4069-74 pubmed publisher
Mannelqvist M, Stefansson I, Wik E, Kusonmano K, Raeder M, Øyan A, et al. Lipocalin 2 expression is associated with aggressive features of endometrial cancer. BMC Cancer. 2012;12:169 pubmed publisher
Mir S, Jin L, Craven R. Neutrophil gelatinase-associated lipocalin (NGAL) expression is dependent on the tumor-associated sigma-2 receptor S2RPgrmc1. J Biol Chem. 2012;287:14494-501 pubmed publisher
Guttman Yassky E, Lowes M, Fuentes Duculan J, Zaba L, Cardinale I, Nograles K, et al. Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis. J Immunol. 2008;181:7420-7 pubmed
Smith E, Zurakowski D, Saad A, Scott R, Moses M. Urinary biomarkers predict brain tumor presence and response to therapy. Clin Cancer Res. 2008;14:2378-86 pubmed publisher
Gupta K, Shukla M, Cowland J, Malemud C, Haqqi T. Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9. Arthritis Rheum. 2007;56:3326-35 pubmed
Pitashny M, Schwartz N, Qing X, Hojaili B, Aranow C, Mackay M, et al. Urinary lipocalin-2 is associated with renal disease activity in human lupus nephritis. Arthritis Rheum. 2007;56:1894-903 pubmed

product information

master code :

MAB1757

SKU :

MAB1757-100

product name :

Human Lipocalin-2/NGAL Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human Lipocalin-2/NGAL Antibody from R&D Systems is a rat monoclonal antibody to Lipocalin-2/NGAL. This antibody reacts with human,mouse,rat. The Human Lipocalin-2/NGAL Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.

target :

Lipocalin-2/NGAL

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

220310

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Lipocalin-2/NGAL, Gln21-Gly198, Accession # P80188

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human Lipocalin-2/NGAL in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human (rh) Lipocalin-1 or rmLipocalin-2. This antibody also recognizes human Lipocalin-2/MMP-9 complexes in Western blots under non-reducing conditions.

gene symbol :

LCN2

top caption :

Detection of Human Lipocalin-2/NGAL antibody by Western Blot.

accessionNumbers :

P80188

applications :

Western Blot,Immunohistochemistry,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

469 USD

alt names :

24p3, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, HNL, LCN2, lipocalin 2, lipocalin 2 (oncogene 24p3), Lipocalin2, Lipocalin-2, migration-stimulating factor inhibitor, MSFI, neutrophil gelatinase-associated lipocalin, NGAL, NGALlipocalin-2, Oncogene 24p3, p25, Siderocalin, Uterocalin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage