product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Dectin-1/CLEC7A Antibody
catalog :
MAB17561
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
218820
reactivity :
mouse
application :
immunohistochemistry, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 6
Reference
Zhou X, Brown B, Siegel A, El Masry M, Zeng X, Song W, et al. Exosome-Mediated Crosstalk between Keratinocytes and Macrophages in Cutaneous Wound Healing. ACS Nano. 2020;14:12732-12748 pubmed publisher
Liu J, Wu C, Li X, Yan Q, Reaney M, Jiang Z. Xylose rich heteroglycan from flaxseed gum mediates the immunostimulatory effects on macrophages via TLR2 activation. Carbohydr Polym. 2019;213:59-69 pubmed publisher
. Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking ?-glucans. PLoS ONE. 2015;10:e0119244 pubmed publisher
Dong B, Li D, Li R, Chen S, Liu W, Liu W, et al. A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans. PLoS ONE. 2014;9:e114113 pubmed publisher
Yáñez A, Hassanzadeh Kiabi N, Ng M, Megías J, Subramanian A, Liu G, et al. Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce. Eur J Immunol. 2013;43:2114-25 pubmed publisher
Ozment Skelton T, deFluiter E, Ha T, Li C, Graves B, Ferguson D, et al. Leukocyte Dectin-1 expression is differentially regulated in fungal versus polymicrobial sepsis. Crit Care Med. 2009;37:1038-45 pubmed publisher
product information
master code :
MAB17561
SKU :
MAB17561
product name :
Mouse Dectin-1/CLEC7A Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Dectin-1/CLEC7A Antibody from R&D Systems is a rat monoclonal antibody to Dectin-1/CLEC7A. This antibody reacts with mouse. The Mouse Dectin-1/CLEC7A Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunohistochemistry,Blockade of Receptor-ligand Interaction,CyTOF-ready.
target :
Dectin-1/CLEC7A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
218820
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Dectin-1/CLEC7A, Phe69-Leu244, Accession # Q6QLQ4
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse Dectin-1/CLEC7A in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Dectin-1 is observed and no cross-reactivity with recombinant mouse Dectin-2 or rhDLEC is observed.
gene symbol :
CLEC7A
accessionNumbers :
Q6QLQ4
applications :
Flow Cytometry,Neutralization,Immunohistochemistry,Blockade of Receptor-ligand Interaction,CyTOF-ready
USD :
439 USD
alt names :
Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.