This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human TIM-1/KIM-1/HAVCR Antibody
catalog :
MAB1750
quantity :
100 ug (also 25 ug, 500 ug)
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
219211
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, western blot knockout validation
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 1a
Wang J, Qiao L, Hou Z, Luo G. TIM-1 Promotes Hepatitis C Virus Cell Attachment and Infection. J Virol. 2017;91: pubmed publisher
  • immunohistochemistry; human; loading ...; fig 4a
  • immunocytochemistry; mouse; loading ...; fig 3e
  • immunohistochemistry; mouse; loading ...; fig 4a
Arai S, Kitada K, Yamazaki T, Takai R, Zhang X, Tsugawa Y, et al. Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice. Nat Med. 2016;22:183-93 pubmed publisher
Herrador A, Fedeli C, Radulovic E, Campbell K, Moreno H, Gerold G, et al. Dynamic Dystroglycan Complexes Mediate Cell Entry of Lassa Virus. MBio. 2019;10: pubmed publisher
Weissenbacher A, Lo Faro L, Boubriak O, Soares M, Roberts I, Hunter J, et al. Twenty-four-hour normothermic perfusion of discarded human kidneys with urine recirculation. Am J Transplant. 2019;19:178-192 pubmed publisher
Niu J, Jiang Y, Xu H, Zhao C, Zhou G, Chen P, et al. TIM-1 Promotes Japanese Encephalitis Virus Entry and Infection. Viruses. 2018;10: pubmed publisher
Maydan O, McDade P, Liu Y, Wu X, Matsell D, Eddy A. Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy. Physiol Rep. 2018;6:e13654 pubmed publisher
Younan P, Iampietro M, Nishida A, Ramanathan P, Santos R, Dutta M, et al. Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm. MBio. 2017;8: pubmed publisher
Das A, Hirai Yuki A, Gonzalez Lopez O, Rhein B, Moller Tank S, Brouillette R, et al. TIM1 (HAVCR1) Is Not Essential for Cellular Entry of Either Quasi-enveloped or Naked Hepatitis A Virions. MBio. 2017;8: pubmed publisher
Fan H, Qiao L, Kang K, Fan J, Wei W, Luo G. Attachment and Postattachment Receptors Important for Hepatitis C Virus Infection and Cell-to-Cell Transmission. J Virol. 2017;91: pubmed publisher
Aagaard K, Lahon A, Suter M, Arya R, Seferovic M, Vogt M, et al. Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017;7:41389 pubmed publisher
Aravena O, Ferrier A, Menon M, Mauri C, Aguillon J, Soto L, et al. TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients. Arthritis Res Ther. 2017;19:8 pubmed publisher
Kishimoto W, Nishikori M, Arima H, Miyoshi H, Sasaki Y, Kitawaki T, et al. Expression of Tim-1 in primary CNS lymphoma. Cancer Med. 2016;5:3235-3245 pubmed publisher
Kuroda M, Fujikura D, Noyori O, Kajihara M, Maruyama J, Miyamoto H, et al. A polymorphism of the TIM-1 IgV domain: implications for the susceptibility to filovirus infection. Biochem Biophys Res Commun. 2014;455:223-8 pubmed publisher
Todorovic Z, Medic B, Basta Jovanovic G, Radojevic Skodric S, Stojanovic R, Rovcanin B, et al. Acute pretreatment with chloroquine attenuates renal I/R injury in rats. PLoS ONE. 2014;9:e92673 pubmed publisher
Wilkinson R, Wang X, Kassianos A, Zuryn S, Roper K, Osborne A, et al. Laser capture microdissection and multiplex-tandem PCR analysis of proximal tubular epithelial cell signaling in human kidney disease. PLoS ONE. 2014;9:e87345 pubmed publisher
Jemielity S, Wang J, Chan Y, Ahmed A, Li W, Monahan S, et al. TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog. 2013;9:e1003232 pubmed publisher
Ivie S, Fennessey C, Sheng J, Rubin D, McClain M. Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ?-toxin. PLoS ONE. 2011;6:e17787 pubmed publisher
Idali F, Wahlstrom J, Dahlberg B, Khademi M, Olsson T, Eklund A, et al. Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis. Respir Res. 2009;10:42 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB1750
SKU :
MAB1750-100
product name :
Human TIM-1/KIM-1/HAVCR Antibody
description :
The Human TIM-1/KIM-1/HAVCR Antibody from R&D Systems is a mouse monoclonal antibody to TIM-1/KIM-1/HAVCR. This antibody reacts with human. The Human TIM-1/KIM-1/HAVCR Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, CyTOF-ready.
target :
TIM-1/KIM-1/HAVCR
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
219211
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TIM-1/KIM-1/HAVCR, Ser21-Thr288, Accession # AAC39862
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human TIM-1/KIM-1/HAVCR in direct ELISAs and Western blots. Does not cross-react with recombinant mouse (rm) TIM-1, rmTIM-2, or rhTIM-3.
gene symbol :
HAVCR1
catalog number base :
MAB1750
accessionNumbers :
AAC39862
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, CyTOF-ready
extended description :
Clone 219211 was used by HLDA to establish CD designation
2020 USD :
339
2021 USD :
369 USD
product details :
Clone 219211 was used by HLDA to establish CD designation
alt names :
CD365, HAVCR1, HAVCR-1, HAVCRT cell immunoglobin domain and mucin domain protein 1, hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM1, TIM-1TIM, TIM1TIMD-1, TIMD1T-cell membrane protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.