Human TIM-1/KIM-1/HAVCR Antibody | R&D Systems MAB1750-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TIM-1/KIM-1/HAVCR Antibody

catalog :

MAB1750-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

219211

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 24

Reference
Hong S, Song M, Miyoshi T, Morizane R, Bonventre J, Lee L. Dynamic Kidney Organoid Microphysiological Analysis Platform. bioRxiv. 2024;: pubmed publisher
Liang Z, Pan J, Xie S, Yang X, Cao R. Interaction between hTIM-1 and Envelope Protein Is Important for JEV Infection. Viruses. 2023;15: pubmed publisher
Zhang B, Wan S, Liu H, Qiu Q, Chen H, Chen Z, et al. Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway. Oxid Med Cell Longev. 2022;2022:5992436 pubmed publisher
Chen L, Qing J, Xiao Y, Huang X, Chi Y, Chen Z. TIM-1 promotes proliferation and metastasis, and inhibits apoptosis, in cervical cancer through the PI3K/AKT/p53 pathway. BMC Cancer. 2022;22:370 pubmed publisher
Zhang Y, Xiang C, Gong L, Zhang Y, Zhen J, Hu Z, et al. Kidney injury molecule-1 levels are associated with therapeutic outcomes and renal tubulointerstitial injury severity in idiopathic membranous nephropathy. Exp Ther Med. 2021;22:1434 pubmed publisher
Dabbagh D, He S, Hetrick B, Chilin L, Andalibi A, Wu Y. Identification of the SHREK family of proteins as broad-spectrum host antiviral factors. bioRxiv. 2021;: pubmed publisher
Herrador A, Fedeli C, Radulovic E, Campbell K, Moreno H, Gerold G, et al. Dynamic Dystroglycan Complexes Mediate Cell Entry of Lassa Virus. MBio. 2019;10: pubmed publisher
Niu J, Jiang Y, Xu H, Zhao C, Zhou G, Chen P, et al. TIM-1 Promotes Japanese Encephalitis Virus Entry and Infection. Viruses. 2018;10: pubmed publisher
Weissenbacher A, Lo Faro L, Boubriak O, Soares M, Roberts I, Hunter J, et al. Twenty-four-hour normothermic perfusion of discarded human kidneys with urine recirculation. Am J Transplant. 2019;19:178-192 pubmed publisher
Maydan O, McDade P, Liu Y, Wu X, Matsell D, Eddy A. Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy. Physiol Rep. 2018;6:e13654 pubmed publisher
Younan P, Iampietro M, Nishida A, Ramanathan P, Santos R, Dutta M, et al. Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm. MBio. 2017;8: pubmed publisher
Das A, Hirai Yuki A, Gonzalez Lopez O, Rhein B, Moller Tank S, Brouillette R, et al. TIM1 (HAVCR1) Is Not Essential for Cellular Entry of Either Quasi-enveloped or Naked Hepatitis A Virions. MBio. 2017;8: pubmed publisher
Van Ness K, Chang S, Weber E, Zumpano D, Eaton D, Kelly E. Microphysiological Systems to Assess Nonclinical Toxicity. Curr Protoc Toxicol. 2017;73:14.18.1-14.18.28 pubmed publisher
Fan H, Qiao L, Kang K, Fan J, Wei W, Luo G. Attachment and Postattachment Receptors Important for Hepatitis C Virus Infection and Cell-to-Cell Transmission. J Virol. 2017;91: pubmed publisher
Aagaard K, Lahon A, Suter M, Arya R, Seferovic M, Vogt M, et al. Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017;7:41389 pubmed publisher
Aravena O, Ferrier A, Menon M, Mauri C, Aguillon J, Soto L, et al. TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients. Arthritis Res Ther. 2017;19:8 pubmed publisher
Wang J, Qiao L, Hou Z, Luo G. TIM-1 Promotes Hepatitis C Virus Cell Attachment and Infection. J Virol. 2017;91: pubmed publisher
Kishimoto W, Nishikori M, Arima H, Miyoshi H, Sasaki Y, Kitawaki T, et al. Expression of Tim-1 in primary CNS lymphoma. Cancer Med. 2016;5:3235-3245 pubmed publisher
Kuroda M, Fujikura D, Noyori O, Kajihara M, Maruyama J, Miyamoto H, et al. A polymorphism of the TIM-1 IgV domain: implications for the susceptibility to filovirus infection. Biochem Biophys Res Commun. 2014;455:223-8 pubmed publisher
Todorovic Z, Medic B, Basta Jovanovic G, Radojevic Skodric S, Stojanovic R, Rovcanin B, et al. Acute pretreatment with chloroquine attenuates renal I/R injury in rats. PLoS ONE. 2014;9:e92673 pubmed publisher
Wilkinson R, Wang X, Kassianos A, Zuryn S, Roper K, Osborne A, et al. Laser capture microdissection and multiplex-tandem PCR analysis of proximal tubular epithelial cell signaling in human kidney disease. PLoS ONE. 2014;9:e87345 pubmed publisher
Jemielity S, Wang J, Chan Y, Ahmed A, Li W, Monahan S, et al. TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog. 2013;9:e1003232 pubmed publisher
Ivie S, Fennessey C, Sheng J, Rubin D, McClain M. Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ?-toxin. PLoS ONE. 2011;6:e17787 pubmed publisher
Idali F, Wahlstrom J, Dahlberg B, Khademi M, Olsson T, Eklund A, et al. Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis. Respir Res. 2009;10:42 pubmed publisher

product information

master code :

MAB1750

SKU :

MAB1750-100

product name :

Human TIM-1/KIM-1/HAVCR Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human TIM-1/KIM-1/HAVCR Antibody from R&D Systems is a mouse monoclonal antibody to TIM-1/KIM-1/HAVCR. This antibody reacts with human,mouse,rat. The Human TIM-1/KIM-1/HAVCR Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Blocking,Cell-based ELISA,Flow Cytometry,Western Blot,Functional Assay,Immunohistochemistry-Paraffin,CyTOF-ready.

target :

TIM-1/KIM-1/HAVCR

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

219211

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TIM-1/KIM-1/HAVCR, Ser21-Thr288, Accession # AAC39862

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human TIM-1/KIM-1/HAVCR in direct ELISAs and Western blots. Does not cross-react with recombinant mouse (rm) TIM-1, rmTIM-2, or rhTIM-3.

gene symbol :

HAVCR1

Antibody validation :

Biological Validation

top caption :

Detection of Human TIM-1/KIM-1/HAVCR antibody by Western Blot.

accessionNumbers :

AAC39862

applications :

Immunohistochemistry,Immunocytochemistry,Blocking,Cell-based ELISA,Flow Cytometry,Western Blot,Functional Assay,Immunohistochemistry-Paraffin,CyTOF-ready

extended description :

Clone 219211 was used by HLDA to establish CD designation

USD :

489 USD

product details :

Clone 219211 was used by HLDA to establish CD designation

alt names :

CD365, HAVCR1, HAVCR-1, HAVCRT cell immunoglobin domain and mucin domain protein 1, hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM1, TIM-1TIM, TIM1TIMD-1, TIMD1T-cell membrane protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage