product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Desmoglein-3 Antibody
catalog :
MAB1720
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
216519
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 6
Reference
Sharafeldin M, Chen T, Ozkaya G, Choudhary D, Molinolo A, Gutkind J, et al. Detecting cancer metastasis and accompanying protein biomarkers at single cell levels using a 3D-printed microfluidic immunoarray. Biosens Bioelectron. 2021;171:112681 pubmed publisher
Bunbanjerdsuk S, Vorasan N, Saethang T, Pongrujikorn T, Pangpunyakulchai D, Mongkonsiri N, et al. Oncoproteomic and gene expression analyses identify prognostic biomarkers for second primary malignancy in patients with head and neck squamous cell carcinoma. Mod Pathol. 2019;: pubmed publisher
Sumitomo T, Mori Y, Nakamura Y, Honda Ogawa M, Nakagawa S, Yamaguchi M, et al. Streptococcal Cysteine Protease-Mediated Cleavage of Desmogleins Is Involved in the Pathogenesis of Cutaneous Infection. Front Cell Infect Microbiol. 2018;8:10 pubmed publisher
Horimasu Y, Ishikawa N, Taniwaki M, Yamaguchi K, Hamai K, Iwamoto H, et al. Gene expression profiling of idiopathic interstitial pneumonias (IIPs): identification of potential diagnostic markers and therapeutic targets. BMC Med Genet. 2017;18:88 pubmed publisher
Chernyavsky A, Arredondo J, Vetter D, Grando S. Central role of alpha9 acetylcholine receptor in coordinating keratinocyte adhesion and motility at the initiation of epithelialization. Exp Cell Res. 2007;313:3542-55 pubmed
Chernyavsky A, Arredondo J, Kitajima Y, Sato Nagai M, Grando S. Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: characterization of novel signaling pathways downstream of pemphigus vulgaris antigens. J Biol Chem. 2007;282:13804-12 pubmed
product information
master code :
MAB1720
SKU :
MAB1720
product name :
Human Desmoglein-3 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human Desmoglein-3 Antibody from R&D Systems is a mouse monoclonal antibody to Desmoglein-3. This antibody reacts with human. The Human Desmoglein-3 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry.
target :
Desmoglein-3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
216519
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Desmoglein-3, Glu50-Arg615, Accession # P32926
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Desmoglein-3 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) Desmoglein-1, rhDesmoglein-2, or rhCadherin-17 is observed.
gene symbol :
DSG3
top caption :
Detection of Human Desmoglein-3 antibody by Western Blot.
accessionNumbers :
P32926
applications :
Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry
USD :
559 USD
alt names :
Cadherin family member 6, CDHF6, CDHF6130-kD pemphigus vulgaris antigen, desmoglein 3, desmoglein 3 (pemphigus vulgaris antigen), desmoglein-3, Desmoglein3, DKFZp686P23184,130 kDa pemphigus vulgaris antigen, DSG3, pemphigus vulgaris antigen, PVA
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.