Human CD11b/Integrin alpha M Antibody | R&D Systems MAB16992 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD11b/Integrin alpha M Antibody

catalog :

MAB16992

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

238439

reactivity :

human, rat

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Kendall T, Jimenez Ramos M, Turner F, Ramachandran P, Minnier J, McColgan M, et al. An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease. Nat Med. 2023;29:2939-2953 pubmed publisher
Horiguchi T, Tanimura A, Miyoshi K, Hagita H, Minami H, Noma T. The Effect of Heterozygous Mutation of Adenylate Kinase 2 Gene on Neutrophil Differentiation. Int J Mol Sci. 2022;23: pubmed publisher
Almengl xf3 C, Fu X, Flores Arias M, Fern xe1 ndez x, Vi xf1 uela J, Mart xed nez Cereijo J, et al. Synergism between obesity and HFpEF on neutrophils phenotype and its regulation by adipose tissue-molecules and SGLT2i dapagliflozin. J Cell Mol Med. 2022;26:4416-4427 pubmed publisher
Noonan J, Grassia G, Macritchie N, Garside P, Guzik T, Bradshaw A, et al. A Novel Triple-Cell Two-Dimensional Model to Study Immune-Vascular Interplay in Atherosclerosis. Front Immunol. 2019;10:849 pubmed publisher
Tanimura A, Horiguchi T, Miyoshi K, Hagita H, Noma T. Differential expression of adenine nucleotide converting enzymes in mitochondrial intermembrane space: a potential role of adenylate kinase isozyme 2 in neutrophil differentiation. PLoS ONE. 2014;9:e89916 pubmed publisher
Izban M, Nowicki B, Nowicki S. 1,25-Dihydroxyvitamin D3 promotes a sustained LPS-induced NF-?B-dependent expression of CD55 in human monocytic THP-1 cells. PLoS ONE. 2012;7:e49318 pubmed publisher
Nakayama H, Yoshizaki F, Prinetti A, Sonnino S, Mauri L, Takamori K, et al. Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms. J Leukoc Biol. 2008;83:728-41 pubmed
Shi Y, Tohyama Y, Kadono T, He J, Miah S, Hazama R, et al. Protein-tyrosine kinase Syk is required for pathogen engulfment in complement-mediated phagocytosis. Blood. 2006;107:4554-62 pubmed

product information

brand :

R&D Systems

master code :

MAB16992

SKU :

MAB16992

product name :

Human CD11b/Integrin alpha M Antibody

unit size :

500 ug (also 25 ug)

seo description :

The Human CD11b/Integrin alpha M Antibody from R&D Systems is a mouse monoclonal antibody to CD11b. This antibody reacts with human,rat. The Human CD11b/Integrin alpha M Antibody has been validated for the following applications: Multiplex Immunofluorescence,Western Blot,Immunohistochemistry.

target :

CD11b/Integrin alpha M

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

238439

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 3-25 ug/mL, Multiplex Immunofluorescence 15 ug/mL

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human CD11b/Integrin alpha M, Phe17-Asn1105, Accession # NP_001139280

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Rat

specificity :

Detects human CD11b/Integrin alpha M in direct ELISAs and Western blots. In Western blots no cross-reactivity with recombinant mouse (rm) Integrins alpha 2, alpha 3, alpha 4, alpha E or rhIntegrins alpha 5, alpha V, ▀1, ▀2, ▀3, or ▀6.

gene symbol :

ITGAM

accessionNumbers :

NP_001139280

applications :

Multiplex Immunofluorescence,Immunohistochemistry,Western Blot

USD :

569 USD

alt names :

antigen CD11b (p170), CD11 antigen-like family member B, CD11b, CD11b antigen, Cell surface glycoprotein MAC-1 subunit alpha, Complement component 3 receptor 3 subunit, CR-3 alpha chain, CR3A, CR3AMGC117044, Integrin alpha M, integrin alpha-M, integrin, alpha M (complement component 3 receptor 3 subunit), ITGAM, Leukocyte adhesion receptor MO1, MAC-1, MAC1A, macrophage antigen alpha polypeptide, MO1A, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit, SLEB6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage