Human/Mouse/Rat HMGB1/HMG-1 Antibody | R&D Systems MAB16901 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat HMGB1/HMG-1 Antibody

catalog :

MAB16901

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

951420

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Chi G, Lu J, He T, Wang Y, Zhou X, Zhang Y, et al. High mobility group box-1 protein promotes astrocytic CCL5 production through the MAPK/NF-κB pathway following spinal cord injury. Sci Rep. 2024;14:22344 pubmed publisher
Salama R, Ahmed R, Farid A, AbdElSattar B, AbdelBaset R, Youssef M, et al. Gastroprotective effect of dapagliflozin in ethanol-induced gastric lesions in rats: Crosstalk between HMGB1/RAGE/PTX3 and TLR4/MyD88/VEGF/PDGF signaling pathways. Int Immunopharmacol. 2023;115:109686 pubmed publisher
Techarang T, Jariyapong P, Viriyavejakul P, Glaharn S, Srisook C, Punsawad C. Protective Effect of an Anti-HMGB-1 Neutralizing Antibody on Hemozoin-Induced Alveolar Epithelial Cell in a Model of Malaria Associated ALI/ARDS. Iran J Parasitol. 2021;16:366-376 pubmed publisher
Lian D, Liu J, Han R, Jin J, Zhu L, Zhang Y, et al. Kakonein restores diabetes-induced endothelial junction dysfunction via promoting autophagy-mediated NLRP3 inflammasome degradation. J Cell Mol Med. 2021;25:7169-7180 pubmed publisher
Bi X, Jiang B, Zhou J, Fan X, Yan X, Liang J, et al. CBP Bromodomain Inhibition Rescues Mice From Lethal Sepsis Through Blocking HMGB1-Mediated Inflammatory Responses. Front Immunol. 2020;11:625542 pubmed publisher
Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M. Anti-high mobility group box-1 (HMGB1) antibody inhibits hemorrhage-induced brain injury and improved neurological deficits in rats. Sci Rep. 2017;7:46243 pubmed publisher

product information

master code :

MAB16901

SKU :

MAB16901

product name :

Human/Mouse/Rat HMGB1/HMG-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat HMGB1/HMG-1 Antibody from R&D Systems is a rat monoclonal antibody to HMGB1/HMG-1. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat HMGB1/HMG-1 Antibody has been validated for the following applications: In vivo assay,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Immunohistochemistry.

target :

HMGB1/HMG-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

951420

conjugate :

Unconjugated

host :

Rat

immunogen :

Human HMGB1/HMG-1 synthetic peptide between amino acids Lys50-Ser100, Accession # P09429

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human, mouse, and rat HMGB1/HMG-1 in Western blot.

gene symbol :

HMGB1

top caption :

Detection of Human, Mouse, and Rat HMGB1/HMG-1 antibody by Western Blot.

accessionNumbers :

P09429

applications :

In vivo assay,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Immunohistochemistry

USD :

459 USD

alt names :

Amphoterin, high mobility group box 1, High mobility group protein 1, high mobility group protein B1, high-mobility group (nonhistone chromosomal) protein 1, high-mobility group box 1, HMG1, HMG-1, HMG1DKFZp686A04236, HMG3, SBP-1, Sulfoglucuronyl carbohydrate binding protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage