product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse WISP-1/CCN4 Antibody
catalog :
MAB1680-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
214203
reactivity :
human, mouse
application :
western blot, neutralization
more info or order :
citations: 5
Reference
Deng W, Fernandez A, McLaughlin S, Klinke D. WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial-mesenchymal transition. J Biol Chem. 2019;294:5261-5280 pubmed publisher
Jin S, Chen Z, Ding X, Zhao X, Jiang X, Tong Y, et al. MECHANICAL VENTILATION AUGMENTS POLY(I:C)INDUCED LUNG INJURY VIA A WISP1-INTEGRIN β3 DEPENDENT PATHWAY IN MICE. Mol Med. 2016;22:54-63 pubmed publisher
Gurbuz I, Ferralli J, Roloff T, Chiquet Ehrismann R, Asparuhova M. SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients. Mol Cancer. 2014;13:22 pubmed publisher
Kulkarni Y, Chambers E, McGray A, Ware J, Bramson J, Klinke D. A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model. Integr Biol (Camb). 2012;4:925-36 pubmed publisher
Heise R, Stober V, Cheluvaraju C, Hollingsworth J, Garantziotis S. Mechanical stretch induces epithelial-mesenchymal transition in alveolar epithelia via hyaluronan activation of innate immunity. J Biol Chem. 2011;286:17435-44 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB1680
SKU :
MAB1680-100
product name :
Mouse WISP-1/CCN4 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Mouse WISP-1/CCN4 Antibody from R&D Systems is a rat monoclonal antibody to WISP-1/CCN4. This antibody reacts with human,mouse. The Mouse WISP-1/CCN4 Antibody has been validated for the following applications: Western Blot,Neutralization.
target :
WISP-1/CCN4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
214203
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse WISP-1/CCN4, Leu21-Asn367, Accession # O54775
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects mouse WISP-1/CCN4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows approximately 10-30% cross-reactivity with recombinant human (rh) WISP-1 but no cross-reactivity with rhCTGF or rmNOV.
gene symbol :
WISP1
accessionNumbers :
O54775
applications :
Western Blot,Neutralization
USD :
469 USD
alt names :
CCN family member 4, CCN4, CCN4WISP1tc, WISP1, WISP-1, WISP1c, WISP1i, WNT1 induced secreted protein 1, Wnt-1 inducible signaling pathway protein 1, WNT1 inducible signaling pathway protein 1, wnt-1 signaling pathway protein 1, Wnt-1-induced secreted protein, WNT1-inducible-signaling pathway protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.