Human/Mouse/Rat HSP70/HSPA1A Antibody | R&D Systems MAB1663 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat HSP70/HSPA1A Antibody

catalog :

MAB1663

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

242707

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 17

Reference
Kim R, Kim J. Engineered Extracellular Vesicles with Compound-Induced Cargo Delivery to Solid Tumors. Int J Mol Sci. 2023;24: pubmed publisher
Nickelsen A, G xf6 tz C, Lenz F, Niefind K, K xf6 nig S, Jose J. Analyzing the interactome of human CK2β in prostate carcinoma cells reveals HSP70-1 and Rho guanin nucleotide exchange factor 12 as novel interaction partners. FASEB Bioadv. 2023;5:114-130 pubmed publisher
Pittenger M, EGHTESAD S, Sanchez P, Liu X, Wu Z, Chen L, et al. MSC Pretreatment for Improved Transplantation Viability Results in Improved Ventricular Function in Infarcted Hearts. Int J Mol Sci. 2022;23: pubmed publisher
Sonntag R, Penners C, Kohlhepp M, Haas U, Lambertz D, Kroh A, et al. Cyclin E1 in Murine and Human Liver Cancer: A Promising Target for Therapeutic Intervention during Tumour Progression. Cancers (Basel). 2021;13: pubmed publisher
Szczuka I, Wierzbicki J, Serek P, Szczęśniak Sięga B, Krzystek Korpacka M. Heat Shock Proteins HSPA1 and HSP90AA1 Are Upregulated in Colorectal Polyps and Can Be Targeted in Cancer Cells by Anti-Inflammatory Oxicams with Arylpiperazine Pharmacophore and Benzoyl Moiety Substitutions at Thiazine Ring. Biomolecules. 2021;11: pubmed publisher
Freisleben F, Modemann F, Muschhammer J, Stamm H, Brauneck F, Krispien A, et al. Mebendazole Mediates Proteasomal Degradation of GLI Transcription Factors in Acute Myeloid Leukemia. Int J Mol Sci. 2021;22: pubmed publisher
Deruelle V, Bouillot S, Job V, Taillebourg E, Fauvarque M, Attree I, et al. The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis. Nat Commun. 2021;12:4024 pubmed publisher
Nik Mohamed Kamal N, Awang R, Mohamad S, Shahidan W. Plasma- and Saliva Exosome Profile Reveals a Distinct MicroRNA Signature in Chronic Periodontitis. Front Physiol. 2020;11:587381 pubmed publisher
Chen B, Chang Y, Lin S, Yang W. Hsc70/Stub1 promotes the removal of individual oxidatively stressed peroxisomes. Nat Commun. 2020;11:5267 pubmed publisher
Dissanayake K, Nõmm M, Lättekivi F, Ressaissi Y, Godakumara K, Lavrits A, et al. Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers. Theriogenology. 2020;149:104-116 pubmed publisher
D Amico L, Menzel U, Prummer M, Müller P, Buchi M, Kashyap A, et al. A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer. J Immunother Cancer. 2019;7:16 pubmed publisher
Takamura Y, Aoki W, Satomura A, Shibasaki S, Ueda M. Small RNAs detected in exosomes derived from the MH7A synovial fibroblast cell line with TNF-α stimulation. PLoS ONE. 2018;13:e0201851 pubmed publisher
Yao Y, Wu J, Gu T, Cheng Y, Li G. Comparative analysis of the interaction of HSPs in dendritic cells, macrophages, RGM-1 cells infected by Helicobacter pylori. Am J Transl Res. 2016;8:4184-4194 pubmed
Mao R, Rubio V, Chen H, Bai L, Mansour O, Shi Z. OLA1 protects cells in heat shock by stabilizing HSP70. Cell Death Dis. 2013;4:e491 pubmed publisher
LIEDEL J, Guo Y, Yu Y, Shiou S, Chen S, Petrof E, et al. Mother's milk-induced Hsp70 expression preserves intestinal epithelial barrier function in an immature rat pup model. Pediatr Res. 2011;69:395-400 pubmed publisher
Fetaud Lapierre V, Pastor C, Farina A, Hochstrasser D, Frossard J, Lescuyer P. Proteomic analysis of heat shock-induced protection in acute pancreatitis. J Proteome Res. 2010;9:5929-42 pubmed publisher
Bhatnagar S, Shinagawa K, Castellino F, Schorey J. Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo. Blood. 2007;110:3234-44 pubmed

product information

brand :

R&D Systems

master code :

MAB1663

SKU :

MAB1663

product name :

Human/Mouse/Rat HSP70/HSPA1A Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat HSP70/HSPA1A Antibody from R&D Systems is a mouse monoclonal antibody to HSP70/HSPA1A. This antibody reacts with human,mouse,primate - chlorocebus aethiops (african green monkey),rat. The Human/Mouse/Rat HSP70/HSPA1A Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Microarray,Simple Western.

target :

HSP70/HSPA1A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

242707

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Simple Western 0.5 ug/mL, Immunohistochemistry 8-25 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human HSP70/HSPA1A, Met1-Asp641, Accession # NP_005336

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Primate - Chlorocebus aethiops (African Green Monkey),Rat

specificity :

Detects the induced form of human and mouse HSP70/HSPA1A in Western blots. In Western blots, no cross-reactivity with the constitutively expressed HSC70 (HSP73) is detected.

gene symbol :

HSPA1A

top caption :

Detection of Human and Mouse HSP70/ HSPA1A antibody by Western Blot.

accessionNumbers :

NP_005336

applications :

Simple Western,Immunohistochemistry,Western Blot,Microarray

USD :

469 USD

alt names :

dnaK-type molecular chaperone HSP70-1, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, Heat shock 70 kDa protein 1/2, heat shock 70 kDa protein 1A/1B, heat shock 70kD protein 1A, heat shock 70kDa protein 1A, heat shock-induced protein, HSP70.1/HSP70.2, HSP70-1, HSP70-1/HSP70-2, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage