Human Podocalyxin Antibody | R&D Systems MAB1658 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Podocalyxin Antibody

catalog :

MAB1658

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

222328

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 21

Reference
Weatherbee B, Weberling A, Gantner C, Iwamoto Stohl L, Barnikel Z, Barrie A, et al. Distinct pathways drive anterior hypoblast specification in the implanting human embryo. Nat Cell Biol. 2024;26:353-365 pubmed publisher
Rakotomamonjy J, Rylaarsdam L, Fares Taie L, McDermott S, Davies D, Yang G, et al. PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model. Cell Rep. 2023;42:112845 pubmed publisher
Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, et al. Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. bioRxiv. 2023;: pubmed publisher
Amo L, D xed ez Garc xed a J, Tamayo Orbegozo E, Maruri N, Larrucea S. Podocalyxin Expressed in Antigen Presenting Cells Promotes Interaction With T Cells and Alters Centrosome Translocation to the Contact Site. Front Immunol. 2022;13:835527 pubmed publisher
Ungricht R, Guibbal L, Lasbennes M, Orsini V, Beibel M, Waldt A, et al. Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis. Cell Stem Cell. 2022;29:160-175.e7 pubmed publisher
Mol xe8 M, Coorens T, Shahbazi M, Weberling A, Weatherbee B, Gantner C, et al. A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre. Nat Commun. 2021;12:3679 pubmed publisher
Lee M, Stebbins M, Jiao H, Huang H, Leiferman E, Walczak B, et al. Comparative evaluation of isogenic mesodermal and ectomesodermal chondrocytes from human iPSCs for cartilage regeneration. Sci Adv. 2021;7: pubmed publisher
Dabbagh D, He S, Hetrick B, Chilin L, Andalibi A, Wu Y. Identification of the SHREK Family of Proteins as Broad-Spectrum Host Antiviral Factors. Viruses. 2021;13: pubmed publisher
Yanagida A, Spindlow D, Nichols J, Dattani A, Smith A, Guo G. Naive stem cell blastocyst model captures human embryo lineage segregation. Cell Stem Cell. 2021;28:1016-1022.e4 pubmed publisher
Dabbagh D, He S, Hetrick B, Chilin L, Andalibi A, Wu Y. Identification of the SHREK family of proteins as broad-spectrum host antiviral factors. bioRxiv. 2021;: pubmed publisher
Townshend R, Shao Y, Wang S, Cortez C, Esfahani S, Spence J, et al. Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells. Front Cell Dev Biol. 2020;8:588941 pubmed publisher
Shahbazi M, Wang T, Tao X, Weatherbee B, Sun L, Zhan Y, et al. Developmental potential of aneuploid human embryos cultured beyond implantation. Nat Commun. 2020;11:3987 pubmed publisher
Tamayo Orbegozo E, Amo L, Riñón M, Nieto N, Amutio E, Maruri N, et al. Podocalyxin promotes proliferation and survival in mature B-cell non-Hodgkin lymphoma cells. Oncotarget. 2017;8:99722-99739 pubmed publisher
Taniguchi K, Shao Y, Townshend R, Cortez C, Harris C, Meshinchi S, et al. An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells. J Cell Biol. 2017;216:3981-3990 pubmed publisher
Shahbazi M, Jedrusik A, Vuoristo S, Recher G, Hupalowska A, Bolton V, et al. Self-organization of the human embryo in the absence of maternal tissues. Nat Cell Biol. 2016;18:700-708 pubmed publisher
Binder Z, Siu I, Eberhart C, Ap Rhys C, Bai R, Staedtke V, et al. Podocalyxin-like protein is expressed in glioblastoma multiforme stem-like cells and is associated with poor outcome. PLoS ONE. 2013;8:e75945 pubmed publisher
Angelotti M, Ronconi E, Ballerini L, Peired A, Mazzinghi B, Sagrinati C, et al. Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury. Stem Cells. 2012;30:1714-25 pubmed publisher
Madden D, Davila Kruger D, Melov S, Bredesen D. Human embryonic stem cells express elevated levels of multiple pro-apoptotic BCL-2 family members. PLoS ONE. 2011;6:e28530 pubmed publisher
Lasagni L, Ballerini L, Angelotti M, Parente E, Sagrinati C, Mazzinghi B, et al. Notch activation differentially regulates renal progenitors proliferation and differentiation toward the podocyte lineage in glomerular disorders. Stem Cells. 2010;28:1674-85 pubmed publisher
Orban T, Apáti A, Nemeth A, Varga N, Krízsik V, Schamberger A, et al. Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery. Stem Cells. 2009;27:1077-87 pubmed publisher
Ronconi E, Sagrinati C, Angelotti M, Lazzeri E, Mazzinghi B, Ballerini L, et al. Regeneration of glomerular podocytes by human renal progenitors. J Am Soc Nephrol. 2009;20:322-32 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB1658

SKU :

MAB1658

product name :

Human Podocalyxin Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human Podocalyxin Antibody from R&D Systems is a mouse monoclonal antibody to Podocalyxin Like. This antibody reacts with human,mouse,virus. The Human Podocalyxin Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Cell Selection,ELISA Capture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot,CyTOF-ready.

target :

Podocalyxin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

222328

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Podocalyxin, Ser23-Arg427, Accession # AAB61574

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Virus

specificity :

Detects human Podocalyxin in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse Podocalyxin or recombinant human Endoglycan is observed.

gene symbol :

PODXL

top caption :

Detection of Podocalyxin antibody in BG01V Human Cells antibody by Flow Cytometry.

accessionNumbers :

AAB61574

applications :

Western Blot,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Cell Selection,ELISA Capture

USD :

499 USD

alt names :

GCTM, Gp200MGC138240, PCLP, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, POD XL, podocalyxin-like, Podocalyxin-like protein 1, PODXL

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage