Human B7-H2 Antibody | R&D Systems MAB165-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human B7-H2 Antibody

catalog :

MAB165-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

136726

reactivity :

human

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 4

Reference
K xfc lp M, Diehl L, Bonig H, Marschalek R. Co-culture of primary human T cells with leukemia cells to measure regulatory T cell expansion. STAR Protoc. 2022;3:101661 pubmed publisher
Külp M, Siemund A, Larghero P, Dietz A, Alten J, Cario G, et al. The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t(4;11) acute lymphoblastic leukemia. iScience. 2022;25:104613 pubmed publisher
Weissmüller S, Semmler L, Kalinke U, Christians S, Muller Berghaus J, Waibler Z. ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation. Blood. 2012;119:6268-77 pubmed publisher
Fos C, Salles A, Lang V, Carrette F, Audebert S, Pastor S, et al. ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse. J Immunol. 2008;181:1969-77 pubmed

product information

master code :

MAB165

SKU :

MAB165-100

product name :

Human B7-H2 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human B7-H2 Antibody from R&D Systems is a mouse monoclonal antibody to B7-H2/ICOSLG. This antibody reacts with human. The Human B7-H2 Antibody has been validated for the following applications: Neutralization,Flow Cytometry,CyTOF-ready.

target :

B7-H2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

136726

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human B7-H2, Asp19-Ser258, Accession # O75144

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human B7-H2 in direct ELISAs. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) B7-1, rhB7-2, rhB7-H1, rhB7-H3, or recombinant mouse B7-H2 is observed.

gene symbol :

ICOSLG

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of B7-H2 antibody in U937 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

O75144

applications :

Neutralization,Flow Cytometry,CyTOF-ready

USD :

479 USD

alt names :

B7H2, B7H2B7 homolog 2, B7-H2B7-related protein 1, B7RP-1, B7RP1B7-like protein Gl50, B7RP-1LICOS, CD275, CD275 antigen, GL50, GL50transmembrane protein B7-H2 ICOS ligand, ICOSL, ICOS-L, ICOSLG, inducible T-cell co-stimulator ligand, KIAA0653ICOS ligand

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage