product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human NOV/CCN3 Antibody
catalog :
MAB1640-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
349 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
209808
reactivity :
human, rat
application :
western blot
more info or order :
citations: 4
Reference
Gao W, Cai L, Xu X, Fan J, Xue X, Yan X, et al. Anti-CTGF single-chain variable fragment dimers inhibit human airway smooth muscle (ASM) cell proliferation by down-regulating p-Akt and p-mTOR levels. PLoS ONE. 2014;9:e113980 pubmed publisher
Riser B, Bhagavathula N, Perone P, Garchow K, Xu Y, Fisher G, et al. Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis. J Cell Commun Signal. 2012;6:97-105 pubmed publisher
Riser B, Najmabadi F, Perbal B, Rambow J, Riser M, Sukowski E, et al. CCN3/CCN2 regulation and the fibrosis of diabetic renal disease. J Cell Commun Signal. 2010;4:39-50 pubmed publisher
Riser B, Najmabadi F, Perbal B, Peterson D, Rambow J, Riser M, et al. CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease. Am J Pathol. 2009;174:1725-34 pubmed publisher
product information
master code :
MAB1640
SKU :
MAB1640-100
product name :
Human NOV/CCN3 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human NOV/CCN3 Antibody from R&D Systems is a mouse monoclonal antibody to NOV/CCN3. This antibody reacts with human,rat. The Human NOV/CCN3 Antibody has been validated for the following applications: ELISA Capture,ELISA Development,Western Blot.
target :
NOV/CCN3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
209808
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human NOV/CCN3, Thr32-Met357, Accession # P48745
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Rat
specificity :
Detects human NOV/CCN3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant mouse NOV, recombinant human (rh) CTGF, or rhWISP-1.
gene symbol :
NOV
accessionNumbers :
P48745
applications :
ELISA Development,Western Blot
USD :
349 USD
alt names :
CCN family member 3, CCN3, CCN3IGF-binding protein 9, IBP-9, IGFBP-9, IGFBP9novH, Insulin-like growth factor-binding protein 9, nephroblastoma overexpressed gene, Nephroblastoma-overexpressed gene protein homolog, NOVH, protein NOV homolog
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.