Human DC-SIGN+DC-SIGNR Antibody | R&D Systems MAB16211 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human DC-SIGN+DC-SIGNR Antibody

catalog :

MAB16211

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DC28

reactivity :

human, mouse

application :

western blot, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Shimojima M, Sugimoto S, Taniguchi S, Maeki T, Yoshikawa T, Kurosu T, et al. N-glycosylation of viral glycoprotein is a novel determinant for the tropism and virulence of highly pathogenic tick-borne bunyaviruses. PLoS Pathog. 2024;20:e1012348 pubmed publisher
Thépaut M, Luczkowiak J, Vivès C, Labiod N, Bally I, Lasala F, et al. DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist. PLoS Pathog. 2021;17:e1009576 pubmed publisher
Shimojima M, Sugimoto S, Taniguchi S, Yoshikawa T, Kurosu T, Saijo M. Efficient functional screening of a cellular cDNA library to identify severe fever with thrombocytopenia syndrome virus entry factors. Sci Rep. 2020;10:5996 pubmed publisher
Wang X, Jiang Y, Yuan M, Chen C, Wang K, Zhang Q, et al. Overexpression of dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related protein in cervical cancer and correlation with squamous cell carcinoma antigen. Oncol Lett. 2017;14:2813-2821 pubmed publisher
Deiva K, Khiati A, Hery C, Salim H, Leclerc P, Horellou P, et al. CCR5-, DC-SIGN-dependent endocytosis and delayed reverse transcription after human immunodeficiency virus type 1 infection in human astrocytes. AIDS Res Hum Retroviruses. 2006;22:1152-61 pubmed
Falkowska E, Durso R, Gardner J, Cormier E, Arrigale R, Ogawa R, et al. L-SIGN (CD209L) isoforms differently mediate trans-infection of hepatoma cells by hepatitis C virus pseudoparticles. J Gen Virol. 2006;87:2571-6 pubmed

product information

master code :

MAB16211

SKU :

MAB16211

product name :

Human DC-SIGN+DC-SIGNR Antibody

unit size :

500 ug (also 25 ug)

description :

The Human DC-SIGN+DC-SIGNR Antibody from R&D Systems is a mouse monoclonal antibody to DC-SIGN+DC-SIGNR. This antibody reacts with human,mouse,primate - cercopithecus aethiops (african green monkey). The Human DC-SIGN+DC-SIGNR Antibody has been validated for the following applications: ELISA Capture,Flow Cytometry,Bioassay,Neutralization,Immunocytochemistry,Western Blot,Adhesion Blockade,CyTOF-ready.

target :

DC-SIGN+DC-SIGNR

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

DC28

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human DC-SIGN, Extracellular domain

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Primate - Cercopithecus aethiops (African Green Monkey)

specificity :

Detects human DC-SIGN in direct ELISAs and Western blots. Was reported to cross-react with human DC-SIGNR as well as DC-SIGN from Pigtailed Macaque and Rhesus Macaque (10).

gene symbol :

CD209

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

applications :

Flow Cytometry,Bioassay,Neutralization,Immunocytochemistry,Western Blot,Adhesion Blockade,CyTOF-ready

USD :

569 USD

alt names :

CD209, CD209;CD209 antigen;CDSIGN;CLEC4L;DC-SIGN;DC-SIGN1;hDC-SIGN, CD209L, CD299, CLEC4L, CLEC4M, DCSIGN, DCSIGN+DCSIGNR, DC-SIGN1, DC-SIGN2, DCSIGNR, LSIGN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage