Human DC-SIGN+DC-SIGNR Antibody | R&D Systems MAB1621 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human DC-SIGN+DC-SIGNR Antibody

catalog :

MAB1621

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

120612

reactivity :

human

application :

immunohistochemistry, flow cytometry

citations: 9

Reference
Aagaard K, Lahon A, Suter M, Arya R, Seferovic M, Vogt M, et al. Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017;7:41389 pubmed publisher
Mazelier M, Rouxel R, Zumstein M, Mancini R, Bell Sakyi L, Lozach P. Uukuniemi Virus as a Tick-Borne Virus Model. J Virol. 2016;90:6784-98 pubmed publisher
Chen Y, Hwang S, Chan V, Chung N, Wang S, Li Z, et al. Binding of HIV-1 gp120 to DC-SIGN promotes ASK-1-dependent activation-induced apoptosis of human dendritic cells. PLoS Pathog. 2013;9:e1003100 pubmed publisher
Mansfield K, Lang S, Gauduin M, Sanford H, Lifson J, Johnson R, et al. Vaccine protection by live, attenuated simian immunodeficiency virus in the absence of high-titer antibody responses and high-frequency cellular immune responses measurable in the periphery. J Virol. 2008;82:4135-48 pubmed publisher
Deiva K, Khiati A, Hery C, Salim H, Leclerc P, Horellou P, et al. CCR5-, DC-SIGN-dependent endocytosis and delayed reverse transcription after human immunodeficiency virus type 1 infection in human astrocytes. AIDS Res Hum Retroviruses. 2006;22:1152-61 pubmed
Falkowska E, Durso R, Gardner J, Cormier E, Arrigale R, Ogawa R, et al. L-SIGN (CD209L) isoforms differently mediate trans-infection of hepatoma cells by hepatitis C virus pseudoparticles. J Gen Virol. 2006;87:2571-6 pubmed
Yearley J, Pearson C, Carville A, Shannon R, Mansfield K. SIV-associated myocarditis: viral and cellular correlates of inflammation severity. AIDS Res Hum Retroviruses. 2006;22:529-40 pubmed
Tassaneetrithep B, Burgess T, Granelli Piperno A, Trumpfheller C, Finke J, Sun W, et al. DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J Exp Med. 2003;197:823-9 pubmed
Wu L, Bashirova A, Martin T, Villamide L, Mehlhop E, Chertov A, et al. Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN. Proc Natl Acad Sci U S A. 2002;99:1568-73 pubmed

product information

brand :

R&D Systems

master code :

MAB1621

SKU :

MAB1621-100

product name :

Human DC-SIGN+DC-SIGNR Antibody

description :

The Human DC-SIGN+DC-SIGNR Antibody from R&D Systems is a mouse monoclonal antibody to DC-SIGN+DC-SIGNR. This antibody reacts with human. The Human DC-SIGN+DC-SIGNR Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, CyTOF-ready.

target :

DC-SIGN+DC-SIGNR

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

120612

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

NIH-3T3 mouse embryonic fibroblast cell line transfected with human DC-SIGNR, Accession # Q9H2X3

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Recognizes both human DC-SIGN and human DC-SIGNR on transfected cells. Does not react with parental mouse cells or irrelevant transfectants.

gene symbol :

CD209

catalog number base :

MAB1621

accessionNumbers :

Q9H2X3

applications :

Flow Cytometry, Immunohistochemistry, CyTOF-ready

2020 USD :

339

2021 USD :

359 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.