product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human FGF-BP Antibody
catalog :
MAB1593
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
196519
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3f, 8e
  • western blot; human; loading ...; fig 7a
Chen X, Miao M, Zhou M, Chen J, Li D, Zhang L, et al. Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. Cell Death Dis. 2021;12:761 pubmed publisher
Kong Y, Lan T, Wang L, Gong C, Lv W, Zhang H, et al. BRD4-specific PROTAC inhibits basal-like breast cancer partially through downregulating KLF5 expression. Oncogene. 2024;43:2914-2926 pubmed publisher
Kong Y, Ren W, Fang H, Shah N, Shi Y, You D, et al. Histone Deacetylase Inhibitors (HDACi) Promote KLF5 Ubiquitination and Degradation in Basal-like Breast Cancer. Int J Biol Sci. 2022;18:2104-2115 pubmed publisher
Wu Y, Qin J, Li F, Yang C, Li Z, Zhou Z, et al. USP3 promotes breast cancer cell proliferation by deubiquitinating KLF5. J Biol Chem. 2019;294:17837-17847 pubmed publisher
Shi P, Liu W, Tala -, Wang H, Li F, Zhang H, et al. Metformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation. Cell Discov. 2017;3:17010 pubmed publisher
Zhou W, Song F, Wu Q, Liu R, Wang L, Liu C, et al. miR-217 inhibits triple-negative breast cancer cell growth, migration, and invasion through targeting KLF5. PLoS ONE. 2017;12:e0176395 pubmed publisher
Zhi X, Zhao D, Zhou Z, Liu R, Chen C. YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor. Am J Pathol. 2012;180:2452-61 pubmed publisher
Jaeger J, Koczan D, Thiesen H, Ibrahim S, Gross G, Spang R, et al. Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues. Clin Cancer Res. 2007;13:806-15 pubmed
product information
master code :
MAB1593
SKU :
MAB1593
product name :
Human FGF-BP Antibody
unit size :
500 ug (also 25 ug)
description :
The Human FGF-BP Antibody from R&D Systems is a mouse monoclonal antibody to FGF-BP. This antibody reacts with human. The Human FGF-BP Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,ELISA Capture.
target :
FGF-BP
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
196519
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human FGF-BP, Val35-Cys234, Accession # Q14512
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human FGF-BP in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant rat FGF-BP is observed.
gene symbol :
FGFBP1
top caption :
Detection of Human FGF-BP by Western Blot
accessionNumbers :
Q14512
applications :
Immunohistochemistry,Western Blot,ELISA Capture
USD :
559 USD
alt names :
17 kDa heparin-binding growth factor-binding protein, FGFBP, FGF-BP, FGFBP1, FGF-BP1, FGFBP-1, FGFBPFGF-binding protein 1, fibroblast growth factor binding protein 1, fibroblast growth factor-binding protein 1, HBp17, HBP1717 kDa HBGF-binding protein, heparin-binding growth factor binding protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.