Human IL-28A/IFN-lambda 2 Antibody | R&D Systems MAB1587 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-28A/IFN-lambda 2 Antibody

catalog :

MAB1587

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

248526

reactivity :

human

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 3

Reference
Groen K, Kuratli R, Sar L, Vasou A, Huber M, Hughes D, et al. Highly sensitive reporter cell line for detection of interferon types I-III and their neutralization by antibodies. Eur J Immunol. 2024;54:e2451325 pubmed publisher
Hong J, Lee J, Zhang Z, Wu Y, Yang M, Liao Y, et al. PRC2-Mediated Epigenetic Suppression of Type I IFN-STAT2 Signaling Impairs Antitumor Immunity in Luminal Breast Cancer. Cancer Res. 2022;82:4624-4640 pubmed publisher
Yin Z, Dai J, Deng J, Sheikh F, Natalia M, Shih T, et al. Type III IFNs are produced by and stimulate human plasmacytoid dendritic cells. J Immunol. 2012;189:2735-45 pubmed publisher

product information

master code :

MAB1587

SKU :

MAB1587

product name :

Human IL-28A/IFN-lambda 2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human IL-28A/IFN-lambda 2 Antibody from R&D Systems is a mouse monoclonal antibody to IL-28A/IFN-lambda 2. This antibody reacts with human. The Human IL-28A/IFN-lambda 2 Antibody has been validated for the following applications: Neutralization,Flow Cytometry.

target :

IL-28A/IFN-lambda 2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

248526

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IL-28A/IFN-lambda 2, Val26-Val200, Accession # Q8IZJ0

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IL-28A/IFN-lambda 2 in direct ELISAs. In direct ELISAs, 83% cross-reactivity with recombinant human (rh) IL-28B/IFN-lambda 3 and no cross-reactivity with recombinant mouse IL-28B/IFN-lambda 3 or rhIL-29/IFN-l1 is observed.

gene symbol :

IFNL2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IL-28A/IFN-?2 Inhibition of EMCV-induced Cytopathy and Neutralization by Human IL-28A/IFN-?2 Antibody.

accessionNumbers :

Q8IZJ0

applications :

Neutralization,Flow Cytometry

USD :

479 USD

alt names :

interleukin-28A, IFN-lambda 2, IL28A, IL-28A, interferon, lambda 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage