product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat ERK1/ERK2 Antibody
catalog :
MAB1576
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
216703
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
citations: 20
Reference
Bharadwaj V, Klukinov M, Cowan R, Mahinparvar N, Clark D, YEOMANS D. Oxytocin Receptors on Calvarial Periosteal Innervation: Therapeutic Target for Post-Traumatic Headache?. Pharmaceutics. 2024;16: pubmed publisher
Xia Q, Mao M, Zhan G, Luo Z, Zhao Y, Li X. SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury. iScience. 2023;26:106953 pubmed publisher
Song P, Choi S, Hwang J, Park H, Kim K, Son H, et al. Chrysanthemum boreale Makino Inhibits Oxidative Stress-Induced Neuronal Damage in Human Neuroblastoma SH-SY5Y Cells by Suppressing MAPK-Regulated Apoptosis. Molecules. 2022;27: pubmed publisher
x15a witalska M, Filip Psurska B, Milczarek M, Psurski M, Moszy x144 ska A, D x105 browska A, et al. Combined anticancer therapy with imidazoacridinone analogue C-1305 and paclitaxel in human lung and colon cancer xenografts-Modulation of tumour angiogenesis. J Cell Mol Med. 2022;26:3950-3964 pubmed publisher
Narahara S, Watanabe T, Nagaoka K, Fujimoto N, Furuta Y, Tanaka K, et al. Clusterin and Related Scoring Index as Potential Early Predictors of Response to Sorafenib in Hepatocellular Carcinoma. Hepatol Commun. 2022;6:1198-1212 pubmed publisher
Soleimanpour E, Bergado Acosta J, Landgraf P, Mayer D, Dankert E, Dieterich D, et al. Regulation of CREB Phosphorylation in Nucleus Accumbens after Relief Conditioning. Cells. 2021;10: pubmed publisher
S xe1 nchez A, Garc xed a Acero M, Paredes A, Quero R, Ortega R, Rojas J, et al. Immunodeficiency in a Patient with 22q11.2 Distal Deletion Syndrome and a p.Ala7dup Variant in the MAPK1 Gene. Mol Syndromol. 2020;11:15-23 pubmed publisher
Beck O, Paret C, Russo A, Burhenne J, Fresnais M, Steimel K, et al. Safety and Activity of the Combination of Ceritinib and Dasatinib in Osteosarcoma. Cancers (Basel). 2020;12: pubmed publisher
Vewinger N, Huprich S, Seidmann L, Russo A, Alt F, Bender H, et al. IGF1R Is a Potential New Therapeutic Target for HGNET-BCOR Brain Tumor Patients. Int J Mol Sci. 2019;20: pubmed publisher
Napolitano G, Esposito A, Choi H, Matarese M, Benedetti V, Di Malta C, et al. mTOR-dependent phosphorylation controls TFEB nuclear export. Nat Commun. 2018;9:3312 pubmed publisher
Shinsuke K, Junya K, Tomonobu U, Yoshiko K, Izumo N, Takahiko S. Chronic irradiation with low-dose-rate 137Cs-? rays inhibits NGF-induced neurite extension of PC12 cells via Ca2+/calmodulin-dependent kinase II activation. J Radiat Res. 2017;:1-7 pubmed publisher
Graziano A, Cardile V, Avola R, Vicario N, Parenti C, Salvatorelli L, et al. Wilms' tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation. Oncotarget. 2017;8:13917-13931 pubmed publisher
Milara J, Cervera A, de Diego A, Sanz C, Juan G, Gavaldá A, et al. Non-neuronal cholinergic system contributes to corticosteroid resistance in chronic obstructive pulmonary disease patients. Respir Res. 2016;17:145 pubmed
Li Y, Choi D, Lee E, Seo S, Lee S, Cho E. Sirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells. J Biol Chem. 2016;291:10277-92 pubmed publisher
Destefanis M, Viano M, Leo C, Gervino G, Ponzetto A, Silvagno F. Extremely low frequency electromagnetic fields affect proliferation and mitochondrial activity of human cancer cell lines. Int J Radiat Biol. 2015;91:964-72 pubmed publisher
Abu El Asrar A, Siddiquei M, Nawaz M, Geboes K, Mohammad G. The proinflammatory cytokine high-mobility group box-1 mediates retinal neuropathy induced by diabetes. Mediators Inflamm. 2014;2014:746415 pubmed publisher
Lo H, Chen C, Yang C, Wu P, Tsou C, Chiang K, et al. The carotenoid lutein enhances matrix metalloproteinase-9 production and phagocytosis through intracellular ROS generation and ERK1/2, p38 MAPK, and RAR? activation in murine macrophages. J Leukoc Biol. 2013;93:723-35 pubmed publisher
Clarke D, Al Ahmad A, Lee B, Parham C, Auckland L, Fertala A, et al. Perlecan Domain V induces VEGf secretion in brain endothelial cells through integrin ?5?1 and ERK-dependent signaling pathways. PLoS ONE. 2012;7:e45257 pubmed publisher
Lane A, Tan J, Hawkins C, Heather A, Davies M. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages. Biochem J. 2010;430:161-9 pubmed publisher
Han Y, Wu G, Deng J, Tao J, Guo L, Tian X, et al. Cellular repressor of E1A-stimulated genes inhibits human vascular smooth muscle cell apoptosis via blocking P38/JNK MAP kinase activation. J Mol Cell Cardiol. 2010;48:1225-35 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB1576
SKU :
MAB1576
product name :
Human/Mouse/Rat ERK1/ERK2 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat ERK1/ERK2 Antibody from R&D Systems is a mouse monoclonal antibody to ERK1/ERK2. This antibody reacts with human,mouse,rat,xenograft. The Human/Mouse/Rat ERK1/ERK2 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Simple Western,Functional Assay.
target :
ERK1/ERK2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
216703
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Immunohistochemistry 8-25 ug/mL
host :
Mouse
immunogen :
E. coli -derived recombinant human ERK1, Met1-Pro379, Accession # P27361
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat,Xenograft
specificity :
Detects human, mouse, and rat ERK1/ERK2 in Western blots.
top caption :
Detection of Human/Mouse/Rat ERK1/ERK2 antibody by Western Blot.
accessionNumbers :
P27361
applications :
Immunohistochemistry,Western Blot,Simple Western,Functional Assay
USD :
479 USD
alt names :
ERK1, ERK-1, ERT1, ERT2, Extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, HS44KDAP, HUMKER1A, Insulin-stimulated MAP2 kinase, MAPK 1, MAPK1, MAPK2, MAPK3, Microtubule-associated protein 2 kinase, mitogen-activated protein kinase 3, p41mapk, p42mapk, p44erk1, p44-ERK1, p44mapk, p44-MAPK, PRKM1, PRKM2, PRKM3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.