Human CCR4 Antibody | R&D Systems MAB1567-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR4 Antibody

catalog :

MAB1567-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

205410

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 27

Reference
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Fang Y, Fan W, Xu X, Janoshazi A, Fargo D, Li X. SIRT1 regulates cardiomyocyte alignment during maturation. J Cell Sci. 2022;135: pubmed publisher
Rouers A, Chng M, Lee B, Rajapakse M, Kaur K, Toh Y, et al. Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection. Cell Rep Med. 2021;2:100278 pubmed publisher
Galbraith M, Kinning K, Sullivan K, Baxter R, Araya P, Jordan K, et al. Seroconversion stages COVID19 into distinct pathophysiological states. elife. 2021;10: pubmed publisher
Nelson M, Knochelmann H, Bailey S, Huff L, Bowers J, Majchrzak Kuligowska K, et al. Identification of human CD4+ T cell populations with distinct antitumor activity. Sci Adv. 2020;6: pubmed publisher
Gruber C, Calis J, Buta S, Evrony G, Martin J, Uhl S, et al. Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Immunity. 2020;53:672-684.e11 pubmed publisher
Martín Fernandez M, Bravo García Morato M, Gruber C, Murias Loza S, Malik M, Alsohime F, et al. Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions. Cell Rep. 2020;31:107633 pubmed publisher
Michlmayr D, Kim E, Rahman A, Raghunathan R, Kim Schulze S, Che Y, et al. Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection. Cell Rep. 2020;31:107569 pubmed publisher
Syu G, Wang S, Ma G, Liu S, Pearce D, Prakash A, et al. Development and application of a high-content virion display human GPCR array. Nat Commun. 2019;10:1997 pubmed publisher
Bath N, Ding X, Wilson N, Verhoven B, Boldt B, Sukhwal A, et al. Desensitization and treatment with APRIL/BLyS blockade in rodent kidney transplant model. PLoS ONE. 2019;14:e0211865 pubmed publisher
Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed publisher
Kap Y, van Driel N, Laman J, Tak P, t Hart B. CD20+ B cell depletion alters T cell homing. J Immunol. 2014;192:4242-53 pubmed publisher
Aruga A, Takeshita N, Kotera Y, Okuyama R, Matsushita N, Ohta T, et al. Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer. Clin Cancer Res. 2013;19:2224-31 pubmed publisher
Duluc D, Gannevat J, Anguiano E, Zurawski S, Carley M, Boreham M, et al. Functional diversity of human vaginal APC subsets in directing T-cell responses. Mucosal Immunol. 2013;6:626-38 pubmed publisher
Chang D, Sui J, Geng S, Muvaffak A, Bai M, Fuhlbrigge R, et al. Humanization of an anti-CCR4 antibody that kills cutaneous T-cell lymphoma cells and abrogates suppression by T-regulatory cells. Mol Cancer Ther. 2012;11:2451-61 pubmed publisher
Maehara T, Moriyama M, Nakashima H, Miyake K, Hayashida J, Tanaka A, et al. Interleukin-21 contributes to germinal centre formation and immunoglobulin G4 production in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. Ann Rheum Dis. 2012;71:2011-19 pubmed publisher
Pandya A, Al Jaderi Z, Høglund R, Holmøy T, Harbo H, Norgauer J, et al. Identification of human NK17/NK1 cells. PLoS ONE. 2011;6:e26780 pubmed publisher
Islam S, Chang D, Colvin R, Byrne M, McCully M, Moser B, et al. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat Immunol. 2011;12:167-77 pubmed publisher
Fifadara N, Aye C, Raghuwanshi S, Richardson R, Ono S. CCR1 expression and signal transduction by murine BMMC results in secretion of TNF-alpha, TGFbeta-1 and IL-6. Int Immunol. 2009;21:991-1001 pubmed publisher
Nakamura M, Jo J, Tabata Y, Ishikawa O. Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model. Am J Pathol. 2008;172:650-8 pubmed publisher
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Ponte A, Marais E, Gallay N, Langonne A, Delorme B, Herault O, et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells. 2007;25:1737-45 pubmed
Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, et al. CD molecules 2006--human cell differentiation molecules. J Immunol Methods. 2007;319:1-5 pubmed
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product information

master code :

MAB1567

SKU :

MAB1567-100

product name :

Human CCR4 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CCR4 Antibody from R&D Systems is a mouse monoclonal antibody to CCR4. This antibody reacts with human,mouse,primate - callithrix jacchus (common marmoset),rat. The Human CCR4 Antibody has been validated for the following applications: CyTof,Flow Cytometry,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-reported.

target :

CCR4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

205410

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Human CCR4 transfectants, Met1-Leu360, Accession # P51679

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Primate - Callithrix jacchus (Common Marmoset),Rat

specificity :

Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects CCR4 on human PBLs and platelets.

gene symbol :

CCR4

top caption :

Detection of CCR4 antibody in Human PBMCs antibody by Flow Cytometry.

accessionNumbers :

P51679

applications :

CyTof,Flow Cytometry,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-reported

extended description :

Clone 205410 was used by HLDA to establish CD designation

USD :

499 USD

product details :

Clone 205410 was used by HLDA to establish CD designation

alt names :

C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4HGCN:14099, CCR-4, CD194, CD194 antigen, chemokine (C-C motif) receptor 4, chemokine (C-C) receptor 4, ChemR13, CKR4MGC88293, CMKBR4k5-5, K5-5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage