product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Podocalyxin Antibody
catalog :
MAB1556
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
192703
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 39
Reference
Pedard M, Prevost L, Carpena C, Holleran B, Desrues L, Dubois M, et al. The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male mice. Nat Commun. 2024;15:8430 pubmed publisher
Despin Guitard E, Rosa V, Plunder S, Mathiah N, Van Schoor K, Nehme E, et al. Non-apical mitoses contribute to cell delamination during mouse gastrulation. Nat Commun. 2024;15:7364 pubmed publisher
Schumacher S, Fernkorn M, Marten M, Chen R, Kim Y, Bedzhov I, et al. Tissue-intrinsic beta-catenin signals antagonize Nodal-driven anterior visceral endoderm differentiation. Nat Commun. 2024;15:5055 pubmed publisher
de Melo G, Perraud V, Alvarez F, Vieites Prado A, Kim S, Kergoat L, et al. Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants. Nat Commun. 2023;14:4485 pubmed publisher
Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, et al. Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. bioRxiv. 2023;: pubmed publisher
Ozguldez H, Govindasamy N, Fan R, Long H, Mildner K, Zeuschner D, et al. Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage. Cell Rep. 2023;42:112313 pubmed publisher
Liang X, Weberling A, Hii C, Zernicka Goetz M, Buckley C. E-cadherin mediates apical membrane initiation site localisation during de novo polarisation of epithelial cavities. EMBO J. 2022;41:e111021 pubmed publisher
Brown B, Boekell K, Stotter B, Talbot B, SCHLONDORFF J. Gain-of-function, focal segmental glomerulosclerosis Trpc6 mutation minimally affects susceptibility to renal injury in several mouse models. PLoS ONE. 2022;17:e0272313 pubmed publisher
Karsten L, Janson N, Le Joncour V, Alam S, Müller B, Tanjore Ramanathan J, et al. Bivalent EGFR-Targeting DARPin-MMAE Conjugates. Int J Mol Sci. 2022;23: pubmed publisher
Halimi R, Levin Zaidman S, Levin Salomon V, Bialik S, Kimchi A. Epiblast fragmentation by shedding-a novel mechanism to eliminate cells in post-implantation mouse embryos. Cell Death Differ. 2022;29:1255-1266 pubmed publisher
Roy Chowdhury N, Hopp I, Zilm P, Murray P, Vasilev K. Silver nanoparticle modified surfaces induce differentiation of mouse kidney-derived stem cells. RSC Adv. 2018;8:20334-20340 pubmed publisher
Langkabel J, Horne A, Bonaguro L, Holsten L, Hesse T, Knaus A, et al. Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs. Nat Commun. 2021;12:7322 pubmed publisher
Salewskij K, Gross Thebing T, Ing Simmons E, Duethorn B, Rieger B, Fan R, et al. Ronin governs the metabolic capacity of the embryonic lineage for post-implantation development. EMBO Rep. 2021;22:e53048 pubmed publisher
Filppu P, Tanjore Ramanathan J, Granberg K, Gucciardo E, Haapasalo H, Lehti K, et al. CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity. JCI Insight. 2021;6: pubmed publisher
Molè M, Weberling A, Fassler R, Campbell A, Fishel S, Zernicka Goetz M. Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition. Cell Rep. 2021;34:108834 pubmed publisher
Weberling A, Zernicka Goetz M. Trophectoderm mechanics direct epiblast shape upon embryo implantation. Cell Rep. 2021;34:108655 pubmed publisher
Amadei G, Lau K, De Jonghe J, Gantner C, Sozen B, Chan C, et al. Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro. Dev Cell. 2021;56:366-382.e9 pubmed publisher
Fan R, Kim Y, Wu J, Chen R, Zeuschner D, Mildner K, et al. Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause. Nat Commun. 2020;11:5499 pubmed publisher
Li B, Zhu C, Dong L, Qin J, Xiang W, Davidson A, et al. ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling. J Pathol. 2020;252:274-289 pubmed publisher
Singla S, Iwamoto Stohl L, Zhu M, Zernicka Goetz M. Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism. Nat Commun. 2020;11:2958 pubmed publisher
Kyprianou C, Christodoulou N, Hamilton R, Nahaboo W, Boomgaard D, Amadei G, et al. Basement membrane remodelling regulates mouse embryogenesis. Nature. 2020;582:253-258 pubmed publisher
Neagu A, van Genderen E, Escudero I, Verwegen L, Kurek D, Lehmann J, et al. In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states. Nat Cell Biol. 2020;22:534-545 pubmed publisher
Sozen B, Cox A, De Jonghe J, Bao M, Hollfelder F, Glover D, et al. Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid. Dev Cell. 2019;51:698-712.e8 pubmed publisher
Zhou D, Fu H, Han Y, Zhang L, Liu S, Lin L, et al. Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis. JCI Insight. 2019;4: pubmed publisher
Christodoulou N, Weberling A, Strathdee D, Anderson K, Timpson P, Zernicka Goetz M. Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation. Nat Commun. 2019;10:3557 pubmed publisher
Kasinath V, Yilmam O, Uehara M, Yonar M, Jiang L, Li X, et al. Urine podoplanin heralds the onset of ischemia-reperfusion injury of the kidney. Am J Physiol Renal Physiol. 2019;316:F957-F965 pubmed publisher
Christodoulou N, Kyprianou C, Weberling A, Wang R, Cui G, Peng G, et al. Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation. Nat Cell Biol. 2018;20:1278-1289 pubmed publisher
Naiman N, Fujioka K, Fujino M, Valerius M, Potter S, McMahon A, et al. Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017;41:349-365.e3 pubmed publisher
Legan S, Lee D, Schwarz M. ?5?1 integrin mediates pulmonary epithelial cyst formation. Dev Dyn. 2017;246:475-484 pubmed publisher
Goldspink D, Rookyard C, Tyrrell B, Gadsby J, Perkins J, Lund E, et al. Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres. Open Biol. 2017;7: pubmed publisher
Huang G, Zou B, Lv J, Li T, Huai G, Xiang S, et al. Notoginsenoside R1 attenuates glucose-induced podocyte injury via the inhibition of apoptosis and the activation of autophagy through the PI3K/Akt/mTOR signaling pathway. Int J Mol Med. 2017;39:559-568 pubmed publisher
Fumoto K, Takigawa Imamura H, Sumiyama K, Kaneiwa T, Kikuchi A. Modulation of apical constriction by Wnt signaling is required for lung epithelial shape transition. Development. 2017;144:151-162 pubmed publisher
Sakamoto K, Kuno K, Takemoto M, He P, Ishikawa T, Onishi S, et al. Pituitary adenylate cyclase-activating polypeptide protects glomerular podocytes from inflammatory injuries. J Diabetes Res. 2015;2015:727152 pubmed publisher
Chuang P, Xu J, Dai Y, Jia F, Mallipattu S, Yacoub R, et al. In vivo RNA interference models of inducible and reversible Sirt1 knockdown in kidney cells. Am J Pathol. 2014;184:1940-56 pubmed publisher
Bedzhov I, Zernicka Goetz M. Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation. Cell. 2014;156:1032-44 pubmed publisher
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Sachs N, Claessen N, Aten J, Kreft M, Teske G, Koeman A, et al. Blood pressure influences end-stage renal disease of Cd151 knockout mice. J Clin Invest. 2012;122:348-58 pubmed publisher
Maltby S, Hughes M, Zbytnuik L, Paulson R, McNagny K. Podocalyxin selectively marks erythroid-committed progenitors during anemic stress but is dispensable for efficient recovery. Exp Hematol. 2009;37:10-8 pubmed publisher
Meyer T, Schwesinger C, Wahlefeld J, Dehde S, Kerjaschki D, Becker J, et al. A new mouse model of immune-mediated podocyte injury. Kidney Int. 2007;72:841-52 pubmed
product information
master code :
MAB1556
SKU :
MAB1556
product name :
Mouse Podocalyxin Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Podocalyxin Antibody from R&D Systems is a rat monoclonal antibody to Podocalyxin Like. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse Podocalyxin Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Bioassay,Co-Immunoprecipitation,Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,CyTOF-ready.
target :
Podocalyxin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
192703
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Podocalyxin, Ser21-Arg402, Accession # Q9R0M4
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse Podocalyxin in direct ELISAs and Western blots.
gene symbol :
PODXL
top caption :
Podocalyxin antibody in bEnd by Immunocytochemistry (ICC).3 Mouse Cell Line by Immunocytochemistry (ICC).
accessionNumbers :
Q9R0M4
applications :
Immunohistochemistry,Immunocytochemistry,Bioassay,Co-Immunoprecipitation,Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,CyTOF-ready
USD :
489 USD
alt names :
GCTM, Gp200MGC138240, PCLP, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, POD XL, podocalyxin-like, Podocalyxin-like protein 1, PODXL
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.