Human CCR2 Antibody | R&D Systems MAB150-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR2 Antibody

catalog :

MAB150-100

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

48607

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 46

Reference
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Cassetta L, Fragkogianni S, Sims A, Swierczak A, Forrester L, Zhang H, et al. Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. Cancer Cell. 2019;35:588-602.e10 pubmed publisher
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Sebastiani G, Ventriglia G, Stabilini A, Socci C, Morsiani C, Laurenzi A, et al. Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression. Sci Rep. 2017;7:6897 pubmed publisher
Przybyl J, Kowalewska M, Quattrone A, Dewaele B, Vanspauwen V, Varma S, et al. Macrophage infiltration and genetic landscape of undifferentiated uterine sarcomas. JCI Insight. 2017;2: pubmed publisher
Nieto J, Zamora C, Cantó E, Garcia Planella E, Gordillo J, Ortiz M, et al. CSF-1 regulates the function of monocytes in Crohn's disease patients in remission. Sci Rep. 2017;7:92 pubmed publisher
Maghazachi A, Sand K, Al Jaderi Z. Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity. Front Immunol. 2016;7:437 pubmed
Williams A, José R, Mercer P, Brealey D, Parekh D, Thickett D, et al. Evidence for chemokine synergy during neutrophil migration in ARDS. Thorax. 2017;72:66-73 pubmed publisher
Williams D, Anastos K, Morgello S, Berman J. JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals. J Leukoc Biol. 2015;97:401-12 pubmed publisher
Chandrasekaran P, Moore V, Buckley M, Spurrier J, Kehrl J, Venkatesan S. HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism. PLoS ONE. 2014;9:e86998 pubmed publisher
Pei X, Sun Q, Zhang Y, Wang P, Peng X, Guo C, et al. PC3-secreted microprotein is a novel chemoattractant protein and functions as a high-affinity ligand for CC chemokine receptor 2. J Immunol. 2014;192:1878-86 pubmed publisher
Di Pardo A, Alberti S, Maglione V, Amico E, Cortes E, Elifani F, et al. Changes of peripheral TGF-?1 depend on monocytes-derived macrophages in Huntington disease. Mol Brain. 2013;6:55 pubmed publisher
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product information

brand :

R&D Systems

master code :

MAB150

SKU :

MAB150-100

product name :

Human CCR2 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human CCR2 Antibody from R&D Systems is a mouse monoclonal antibody to CCR2. This antibody reacts with human,mouse,primate - chlorocebus pygerythrus (vervet monkey),rat. The Human CCR2 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry/Immunofluorescence,Flow Cytometry,Neutralization,Cell Culture,Immunohistochemistry-Paraffin,Immunocytochemistry,CyTOF-ready.

target :

CCR2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

48607

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 8-50 ug/mL, CyTOF-ready

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CCR2, Met1-Leu360, Accession # NP_001116868

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human,Mouse,Primate - Chlorocebus pygerythrus (Vervet Monkey),Rat

specificity :

Detects human CCR-2 transfectants but not the parental cell line or CCR-5 transfectants.

gene symbol :

CCR2

top caption :

Detection of CCR2 antibody in Human Blood Monocytes antibody by Flow Cytometry.

accessionNumbers :

NP_001116868

applications :

CyTOF-ready,Flow Cytometry,Immunohistochemistry,Immunocytochemistry/Immunofluorescence,Immunohistochemistry-Paraffin,Neutralization,Immunocytochemistry,Cell Culture

extended description :

Clone 48607 was used by HLDA to establish CD designation

USD :

489 USD

product details :

Clone 48607 was used by HLDA to establish CD designation

alt names :

C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CC-CKR-2CKR2B, CCR2, CCR-2, CCR2A, CCR2B, CD192, CD192 antigen, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-R, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage