product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human BCAM Antibody
catalog :
MAB1481
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
87207
reactivity :
human
application :
western blot, ELISA, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 6
Reference
Sivakumar S, Lieber S, Librizzi D, Keber C, Sommerfeld L, Finkernagel F, et al. Basal cell adhesion molecule promotes metastasis-associated processes in ovarian cancer. Clin Transl Med. 2023;13:e1176 pubmed publisher
Enomoto Okawa Y, Maeda Y, Harashima N, Sugawara Y, Katagiri F, Hozumi K, et al. An Anti-Human Lutheran Glycoprotein Phage Antibody Inhibits Cell Migration on Laminin-511: Epitope Mapping of the Antibody. PLoS ONE. 2017;12:e0167860 pubmed publisher
Cai Z, Zhang A, Choksi S, Li W, Li T, Zhang X, et al. Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration. Cell Res. 2016;26:886-900 pubmed publisher
Chaar V, Laurance S, Lapoumeroulie C, Cochet S, De Grandis M, Colin Y, et al. Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation. J Biol Chem. 2014;289:11512-21 pubmed publisher
Kikkawa Y, Ogawa T, Sudo R, Yamada Y, Katagiri F, Hozumi K, et al. The lutheran/basal cell adhesion molecule promotes tumor cell migration by modulating integrin-mediated cell attachment to laminin-511 protein. J Biol Chem. 2013;288:30990-1001 pubmed publisher
Kikkawa Y, Miwa T, Tohara Y, Hamakubo T, Nomizu M. An antibody to the lutheran glycoprotein (Lu) recognizing the LU4 blood type variant inhibits cell adhesion to laminin ?5. PLoS ONE. 2011;6:e23329 pubmed publisher
product information
master code :
MAB1481
SKU :
MAB1481
product name :
Human BCAM Antibody
unit size :
500 ug (also 25 ug)
description :
The Human BCAM Antibody from R&D Systems is a mouse monoclonal antibody to BCAM/CD239. This antibody reacts with human. The Human BCAM Antibody has been validated for the following applications: Western Blot,Bioassay,Blocking,Epitope Mapping,Neutralization,Flow Cytometry,ELISA Capture (Matched Antibody Pair),CyTOF-ready.
target :
BCAM
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
87207
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human BCAM, Glu32-Ala547, Accession # CAA58449
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human BCAM in ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) ALCAM, rhEpCAM, recombinant mouse (rm) MAdCAM-1, rhMCAM, rhNCAM-L1, rmOCAM, or rmTROP-2 is observed.
gene symbol :
BCAM
top caption :
Detection of BCAM antibody in Huh-7 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
CAA58449
applications :
Western Blot,Bioassay,Blocking,Epitope Mapping,Neutralization,Flow Cytometry,ELISA Capture (Matched Antibody Pair),CyTOF-ready
USD :
559 USD
alt names :
antigen identified by monoclonal F8, Auberger B antigen, basal cell adhesion molecule, basal cell adhesion molecule (Lu and Au blood groups), basal cell adhesion molecule (Lutheran blood group), B-CAM cell surface glycoprotein, B-cell adhesion molecule, CD239, CD239 antigen, F8/G253 antigen, glycoprotein 95kDa, LUAU, Lutheran antigen, Lutheran blood group (Auberger b antigen included), Lutheran blood group glycoprotein, MSK19
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.