Human IL-27 R alpha /WSX-1/TCCR Antibody | R&D Systems MAB1479 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-27 R alpha /WSX-1/TCCR Antibody

catalog :

MAB1479

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

191106

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Martin E, Winter S, Garcin C, Tanita K, Hoshino A, Lenoir C, et al. Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency. Nature. 2024;628:620-629 pubmed publisher
Salameh J, Kumar S, Rivera Cruz C, FIGUEIREDO M. A Second-Generation Nanoluc-IL27 Fusion Cytokine for Targeted-Gene-Therapy Applications. Bioengineering (Basel). 2022;9: pubmed publisher
Zhou W, Yang H, Mei J, Chang K, Lu H, Lai Z, et al. Fructose-1,6-bisphosphate prevents pregnancy loss by inducing decidual COX-2+ macrophage differentiation. Sci Adv. 2022;8:eabj2488 pubmed publisher
Cheng J, Myers T, Levinger C, Kumar P, Kumar J, Goshu B, et al. IL-27 induces IFN/STAT1-dependent genes and enhances function of TIGIT+ HIVGag-specific T cells. iScience. 2022;25:103588 pubmed publisher
Liu S, Han J, Gong H, Li Y, Bao X, Qi J, et al. Soluble interleukin-27 receptor alpha is a valuable prognostic biomarker for acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation. Sci Rep. 2018;8:10328 pubmed publisher
Hosokawa Y, Hosokawa I, Ozaki K, Matsuo T. IL-27 Modulates Chemokine Production in TNF-α -Stimulated Human Oral Epithelial Cells. Cell Physiol Biochem. 2017;43:1198-1206 pubmed publisher
Dietrich C, Candon S, Ruemmele F, Devergne O. A soluble form of IL-27R? is a natural IL-27 antagonist. J Immunol. 2014;192:5382-9 pubmed publisher
Cocco C, Giuliani N, Di Carlo E, Ognio E, Storti P, Abeltino M, et al. Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma. Clin Cancer Res. 2010;16:4188-97 pubmed publisher
Dibra D, Cutrera J, Xia X, Birkenbach M, Li S. Expression of WSX1 in tumors sensitizes IL-27 signaling-independent natural killer cell surveillance. Cancer Res. 2009;69:5505-13 pubmed publisher

product information

master code :

MAB1479

SKU :

MAB1479

product name :

Human IL-27 R alpha /WSX-1/TCCR Antibody

unit size :

500 ug (also 25 ug)

description :

The Human IL-27 R alpha /WSX-1/TCCR Antibody from R&D Systems is a mouse monoclonal antibody to IL-27R alpha/WSX-1/TCCR. This antibody reacts with human,primate - chlorocebus aethiops (african green monkey). The Human IL-27 R alpha /WSX-1/TCCR Antibody has been validated for the following applications: Flow Cytometry,ELISA Development (Capture),Immunoprecipitation,Western Blot.

target :

IL-27 R alpha/WSX-1/TCCR

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

191106

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IL-27 R alpha /WSX-1/TCCR, Gly34-Lys516, Accession # Q6UWB1

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Primate - Chlorocebus aethiops (African Green Monkey)

specificity :

Detects human IL-27 R alpha /WSX-1/TCCR in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human gp130 or recombinant mouse IL-27 Ra is observed.

gene symbol :

IL27RA

accessionNumbers :

Q6UWB1

applications :

Flow Cytometry,ELISA Development (Capture),Immunoprecipitation,Western Blot

USD :

569 USD

alt names :

class I cytokine receptor, CRL1IL-27R, Cytokine receptor-like 1, IL-27 R alpha, IL27R, IL27R alpha, IL27RA, IL-27RA, IL-27R-alpha, interleukin 27 receptor, alpha, interleukin-27 receptor subunit alpha, TCCR, TCCRIL-27 receptor subunit alpha, T-cell cytokine receptor type 1, Type I T-cell cytokine receptor, WSX-1, WSX1IL-27R subunit alpha, zcytor1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage