product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human FGFR3 (IIIb) Antibody
catalog :
MAB1474
quantity :
500 ug (also 25 ug)
price :
579 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
136315
reactivity :
human
application :
neutralization, immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 1
Reference
Tomlinson D, L Hôte C, Kennedy W, Pitt E, Knowles M. Alternative splicing of fibroblast growth factor receptor 3 produces a secreted isoform that inhibits fibroblast growth factor-induced proliferation and is repressed in urothelial carcinoma cell lines. Cancer Res. 2005;65:10441-9 pubmed
product information
master code :
MAB1474
SKU :
MAB1474
product name :
Human FGFR3 (IIIb) Antibody
unit size :
500 ug (also 25 ug)
description :
The Human FGFR3 (IIIb) Antibody from R&D Systems is a mouse monoclonal antibody to FGFR3. This antibody reacts with human. The Human FGFR3 (IIIb) Antibody has been validated for the following applications: Immunoprecipitation,Neutralization.
target :
FGFR3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
136315
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Pool of NS0-derived recombinant human FGFáR3 alpha (IIIb) and Sf21-derived FGF R3 alphaá(IIIc)
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human FGF R3 (IIIb) in direct ELISAs. In direct ELISAs, approximately 25-50% cross-reactivity with recombinant mouse FGF R3 (IIIb) is observed and 12% with recombinant human (rh) FGF R4 is observed and no cross-reactivity with (IIIc) isoforms of rhFGF R3 or any isoforms of rhFGF R1 or rhFGF R2 is observed.
gene symbol :
FGFR3
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
FGF R3 Inhibition of FGF acidic-dependent Cell Proliferation and Neutralization by Human FGF R3 Antibody.
applications :
Immunoprecipitation,Neutralization
USD :
579 USD
alt names :
CD333, CEK, EC 2.7.10, FGF R3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.