Human CCR1 Antibody | R&D Systems MAB145 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR1 Antibody

catalog :

MAB145

quantity :

100 ug (also 25 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

53504

reactivity :

human

application :

flow cytometry

citations: 25

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1a	Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
flow cytometry; human; fig 4	Sullivan A, Wang E, Farrell J, Whitaker P, Faulkner L, Peckham D, et al. ?-Lactam hypersensitivity involves expansion of circulating and skin-resident TH22 cells. J Allergy Clin Immunol. 2018;141:235-249.e8 pubmed publisher
	Tian Y, Seumois G, De Oliveira Pinto L, Mateus J, Herrera de la Mata S, Kim C, et al. Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue Disease. Cell Rep. 2019;29:4482-4495.e4 pubmed publisher
	Fox J, Kausar F, Day A, Osborne M, Hussain K, Mueller A, et al. CXCL4/Platelet Factor 4 is an agonist of CCR1 and drives human monocyte migration. Sci Rep. 2018;8:9466 pubmed publisher
	Vandyke K, Zeissig M, Hewett D, Martin S, Mrozik K, Cheong C, et al. HIF-2Î± Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1. Cancer Res. 2017;77:5452-5463 pubmed publisher
	Kobayashi D, Endo M, Ochi H, Hojo H, Miyasaka M, Hayasaka H. Regulation of CCR7-dependent cell migration through CCR7 homodimer formation. Sci Rep. 2017;7:8536 pubmed publisher
	Bellora F, Dondero A, Corrias M, Casu B, Regis S, Caliendo F, et al. Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages. J Immunol. 2017;199:1516-1525 pubmed publisher
	Maghazachi A, Sand K, Al Jaderi Z. Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity. Front Immunol. 2016;7:437 pubmed
	Williams A, José R, Mercer P, Brealey D, Parekh D, Thickett D, et al. Evidence for chemokine synergy during neutrophil migration in ARDS. Thorax. 2017;72:66-73 pubmed publisher
	Gilliland C, SALANGA C, Kawamura T, Trejo J, Handel T. The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, ?-arrestin-mediated internalization. J Biol Chem. 2013;288:32194-210 pubmed publisher
	Gouwy M, Struyf S, Berghmans N, Vanormelingen C, Schols D, Van Damme J. CXCR4 and CCR5 ligands cooperate in monocyte and lymphocyte migration and in inhibition of dual-tropic (R5/X4) HIV-1 infection. Eur J Immunol. 2011;41:963-73 pubmed publisher
	Jung D, Che Z, Kim J, Kim K, Kim K, Williams D, et al. Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7. Int J Cancer. 2010;127:332-44 pubmed publisher
	Dagouassat M, Suffee N, Hlawaty H, Haddad O, Charni F, Laguillier C, et al. Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. Int J Cancer. 2010;126:1095-108 pubmed publisher
	Fifadara N, Aye C, Raghuwanshi S, Richardson R, Ono S. CCR1 expression and signal transduction by murine BMMC results in secretion of TNF-alpha, TGFbeta-1 and IL-6. Int Immunol. 2009;21:991-1001 pubmed publisher
	Hartl D, Krauss Etschmann S, Koller B, Hordijk P, Kuijpers T, Hoffmann F, et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol. 2008;181:8053-67 pubmed
	Weigt S, Elashoff R, Keane M, Strieter R, Gomperts B, Xue Y, et al. Altered levels of CC chemokines during pulmonary CMV predict BOS and mortality post-lung transplantation. Am J Transplant. 2008;8:1512-22 pubmed publisher
	Joubert P, Lajoie Kadoch S, Welman M, Dragon S, Létuvée S, Tolloczko B, et al. Expression and regulation of CCR1 by airway smooth muscle cells in asthma. J Immunol. 2008;180:1268-75 pubmed
	Gupta S, Fuchs B, Schulz Maronde S, Heitland A, Escher S, Mack M, et al. Intravascular inactivation of CCR5 by n-Nonanoyl-CC chemokine ligand 14 and inhibition of allergic airway inflammation. J Leukoc Biol. 2008;83:765-73 pubmed
	Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, et al. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J Immunol. 2007;179:4272-82 pubmed
	Ponte A, Marais E, Gallay N, Langonne A, Delorme B, Herault O, et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells. 2007;25:1737-45 pubmed
	Haringman J, Smeets T, Reinders Blankert P, Tak P. Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis. Ann Rheum Dis. 2006;65:294-300 pubmed
	Birebent B, Lorho R, Lechartier H, de Guibert S, Alizadeh M, Vu N, et al. Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression. Eur J Immunol. 2004;34:3485-96 pubmed
	Annels N, Willemze A, van der Velden V, Faaij C, van Wering E, Sie Go D, et al. Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL. Blood. 2004;103:2806-8 pubmed
	Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle M, et al. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J Leukoc Biol. 2003;73:584-90 pubmed
	Campbell J, Qin S, Unutmaz D, Soler D, Murphy K, Hodge M, et al. Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J Immunol. 2001;166:6477-82 pubmed

product information

brand :

R&D Systems

master code :

MAB145

SKU :

MAB145-100

product name :

Human CCR1 Antibody

description :

The Human CCR1 Antibody from R&D Systems is a mouse monoclonal antibody to CCR1. This antibody reacts with human. The Human CCR1 Antibody has been validated for the following applications: Flow Cytometry, CyTOF-ready.

target :

CCR1

category :

Primary Antibodies

unit size :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

53504

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Swiss 3T3 mouse cell line transfected with human CCR1, Accession # P32246

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CCR1. Reacts specifically with human CCR1 transfectants and not the parental cell line in flow cytometry. No cross-reactivity with CCR5 transfectants is observed.

gene symbol :

CCR1

catalog number base :

MAB145

accessionNumbers :

P32246

applications :

Flow Cytometry, CyTOF-ready

extended description :

Clone 53504 was used by HLDA to establish CD designation

2020 USD :

339

2021 USD :

359 USD

product details :

Clone 53504 was used by HLDA to establish CD designation

alt names :

C-C chemokine receptor type 1, CC-CKR-1, CCR1, CCR-1, CD191, CD191 antigen, chemokine (C-C motif) receptor 1, CKR1, CKR-1, CMKBR1SCYAR1, CMKR1, HM145C-C CKR-1, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, MIP-1alpha-R, MIP1aR, RANTES receptor, RANTES-R

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.