Human Osteopontin/OPN Antibody | R&D Systems MAB14331-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Osteopontin/OPN Antibody

catalog :

MAB14331-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

223126

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Yang F, Akhtar M, Zhang D, El Mayta R, Shin J, Dorsey J, et al. An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Sci Adv. 2024;10:eadj4678 pubmed publisher
Valad xe3 o P, de Arag xe3 o B, Andrade J, Magalh xe3 es Gomes M, Foureaux G, Joviano Santos J, et al. Abnormalities in the Motor Unit of a Fast-Twitch Lower Limb Skeletal Muscle in Huntington's Disease. ASN Neuro. 2019;11:1759091419886212 pubmed publisher
Ter Braake A, Eelderink C, Zeper L, Pasch A, Bakker S, de Borst M, et al. Calciprotein particle inhibition explains magnesium-mediated protection against vascular calcification. Nephrol Dial Transplant. 2019;: pubmed publisher
Hu H, Liu Z, Liu C. Correlation of OPN gene expression with proliferation and apoptosis of ovarian cancer cells and prognosis of patients. Oncol Lett. 2019;17:2788-2794 pubmed publisher
Iqbal J, Sarkar Dutta M, McRae S, Ramachandran A, Kumar B, Waris G. Osteopontin Regulates Hepatitis C Virus (HCV) Replication and Assembly by Interacting with HCV Proteins and Lipid Droplets and by Binding to Receptors αVβ3 and CD44. J Virol. 2018;92: pubmed publisher
Yamaguchi Y, Shao Z, Sharif S, Du X, Myles T, Merchant M, et al. Thrombin-cleaved fragments of osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage. J Biol Chem. 2013;288:3097-111 pubmed publisher
Mansfield A, Holtan S, Grotz T, Allred J, Jakub J, Erickson L, et al. Regional immunity in melanoma: immunosuppressive changes precede nodal metastasis. Mod Pathol. 2011;24:487-94 pubmed publisher
Das R, Mahabeleshwar G, Kundu G. Osteopontin induces AP-1-mediated secretion of urokinase-type plasminogen activator through c-Src-dependent epidermal growth factor receptor transactivation in breast cancer cells. J Biol Chem. 2004;279:11051-64 pubmed

product information

master code :

MAB14331

SKU :

MAB14331-100

product name :

Human Osteopontin/OPN Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human Osteopontin/OPN Antibody from R&D Systems is a mouse monoclonal antibody to Osteopontin/OPN. This antibody reacts with human. The Human Osteopontin/OPN Antibody has been validated for the following applications: Western Blot,Flow Cytometry,ELISA Development,Immunoprecipitation,Immunohistochemistry-Paraffin,Simple Western.

target :

Osteopontin/OPN

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

223126

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Osteopontin, Ile17-Asn300, Accession # NP_000573.1

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Osteopontin in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant mouse Osteopontin.

gene symbol :

SPP1

top caption :

Detection of Human Osteopontin/OPN antibody by Western Blot.

accessionNumbers :

NP_000573.1

applications :

Western Blot,Flow Cytometry,ELISA Development,Immunoprecipitation,Immunohistochemistry-Paraffin,Simple Western

USD :

489 USD

alt names :

BNSP, Bone sialoprotein 1, Eta-1, MGC110940, Nephropontin, OPN, osteopontin, secreted phosphoprotein 1bone sialoprotein I, early T-lymphocyteactivation 1), secreted phosphoprotein-1 (osteopontin, bone sialoprotein), Spp1, SPP-1, SPP1/CALPHA1 fusion, Urinary stone protein, uropontin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage