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company name :
R&D Systems
product type :
antibody
product name :
Human CD45 Antibody
catalog :
MAB1430
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2D1
reactivity :
human, rat
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 19
Reference
Voss A, Lanjewar S, Sampson M, King A, Hill E, Sing A, et al. Identification of ligand-receptor pairs that drive human astrocyte development. Nat Neurosci. 2023;26:1339-1351 pubmed publisher
Micek H, Rosenstock L, Ma Y, Hielsberg C, Montemorano L, Gari M, et al. Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes. APL Bioeng. 2023;7:016111 pubmed publisher
Ehlers H, Nicolas A, Schavemaker F, Heijmans J, Bulst M, Trietsch S, et al. Vascular inflammation on a chip: A scalable platform for trans-endothelial electrical resistance and immune cell migration. Front Immunol. 2023;14:1118624 pubmed publisher
Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, et al. Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis. Cell. 2020;181:848-864.e18 pubmed publisher
Li X, Tang M, Zhu Q, Wang X, Lin Y, Wang X. The exosomal integrin α5β1/AEP complex derived from epithelial ovarian cancer cells promotes peritoneal metastasis through regulating mesothelial cell proliferation and migration. Cell Oncol (Dordr). 2020;43:263-277 pubmed publisher
Lee J, Kim T, Kim E, Kim A, Lee D, Kwon N, et al. Methionyl-tRNA Synthetase is a Useful Diagnostic Marker for Lymph Node Metastasis in Non-Small Cell Lung Cancer. Yonsei Med J. 2019;60:1005-1012 pubmed publisher
Francisco V, Lino M, Ferreira L. A near infrared light-triggerable modular formulation for the delivery of small biomolecules. J Nanobiotechnology. 2019;17:97 pubmed publisher
Costa M, Kudaravalli J, Ma J, Ho W, Delaria K, Holz C, et al. Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates. Sci Rep. 2019;9:2443 pubmed publisher
Koura S, Salama M, El Hussiny M, Khalil M, Lotfy A, Hassan S, et al. Fluoxetine induces direct inhibitory effects on mesenchymal stem cell‑derived osteoprogenitor cells independent of serotonin concentration. Mol Med Rep. 2019;19:2611-2619 pubmed publisher
Yan J, Zhao Q, Gabrusiewicz K, Kong L, Xia X, Wang J, et al. FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation. Nat Commun. 2019;10:448 pubmed publisher
Fan J, Lee H, Lee W, Lin C, Hsu C, Hsieh C, et al. Potential role of CBX7 in regulating pluripotency of adult human pluripotent-like olfactory stem cells in stroke model. Cell Death Dis. 2018;9:502 pubmed publisher
Du S, McCall N, Park K, Guan Q, Fontina P, Ertel A, et al. Blockade of Tumor-Expressed PD-1 promotes lung cancer growth. Oncoimmunology. 2018;7:e1408747 pubmed publisher
Loi A, Hoonhorst S, van Aalst C, Langereis J, Kamp V, Sluis Eising S, et al. Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients. Respir Res. 2017;18:100 pubmed publisher
Harasymowicz N, Clement N, Azfer A, Burnett R, Salter D, Simpson A. Regional Differences Between Perisynovial and Infrapatellar Adipose Tissue Depots and Their Response to Class II and Class III Obesity in Patients With Osteoarthritis. Arthritis Rheumatol. 2017;69:1396-1406 pubmed publisher
Roberts C, Chen S, Murchison A, Ogle R, Francis M, Ogle R, et al. Preferential Lineage-Specific Differentiation of Osteoblast-Derived Induced Pluripotent Stem Cells into Osteoprogenitors. Stem Cells Int. 2017;2017:1513281 pubmed publisher
Tan C, Shichinohe H, Wang Z, Hamauchi S, Abumiya T, Nakayama N, et al. Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke. Stem Cells Int. 2016;2016:6104780 pubmed
Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed publisher
Keats E, Dominguez J, Grant M, Khan Z. Switch from canonical to noncanonical Wnt signaling mediates high glucose-induced adipogenesis. Stem Cells. 2014;32:1649-60 pubmed publisher
Harvanová D, Tóthová T, Sarissky M, Amrichová J, Rosocha J. Isolation and characterization of synovial mesenchymal stem cells. Folia Biol (Praha). 2011;57:119-24 pubmed
product information
brand :
R&D Systems
master code :
MAB1430
SKU :
MAB1430
product name :
Human CD45 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human CD45 Antibody from R&D Systems is a mouse monoclonal antibody to CD45. This antibody reacts with human,rat. The Human CD45 Antibody has been validated for the following applications: Immunopanning,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,CyTOF-ready,Knockout Validated.
target :
CD45
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
2D1
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Flow Cytometry 0.25 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready, Knockout Validated
host :
Mouse
immunogen :
Human peripheral blood mononuclear cells
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Rat
specificity :
Detects human CD45. This antibody recognizes all isoforms of human CD45.
gene symbol :
PTPRC
top caption :
Detection of CD45 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.
applications :
CyTOF-ready,Knockout Validated,Immunopanning,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
499 USD
alt names :
B220, CD_antigen: CD45, CD45, CD45 antigen, CD45R, EC 3.1.3.48, EC:3.1.3.48, GP180, LCA, L-CA, Leukocyte common antigen, LY5, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.