Human Decorin Antibody | R&D Systems MAB143-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Decorin Antibody

catalog :

MAB143-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

115402

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 16

Reference
Khan S, Sbeity M, Foulquier F, Barr xe9 L, Ouzzine M. TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy. Cell Death Dis. 2021;13:11 pubmed publisher
Iqbal A, May U, Prince S, Järvinen T, Heydemann A. Systemically Administered Homing Peptide Targets Dystrophic Lesions and Delivers Transforming Growth Factor-β (TGFβ) Inhibitor to Attenuate Murine Muscular Dystrophy Pathology. Pharmaceutics. 2021;13: pubmed publisher
Abety A, Pach E, Giebeler N, Fromme J, Aramadhaka L, Mauch C, et al. Loss of ADAM9 Leads to Modifications of the Extracellular Matrix Modulating Tumor Growth. Biomolecules. 2020;10: pubmed publisher
Rezaie R, Falakian Z, Mazloomzadeh S, Ayati M, Morakabati A, Teimouri Dastjerdan M, et al. While Urine and Plasma Decorin Remain Unchanged in Prostate Cancer, Prostatic Tissue Decorin Has a Prognostic Value. Iran Biomed J. 2020;24:229-35 pubmed publisher
Alania Y, Creighton J, Trevelin L, Zamperini C, Bedran Russo A. Regional contribution of proteoglycans to the fracture toughness of the dentin extracellular matrix. J Biomech. 2020;101:109633 pubmed publisher
Katsumata K, Ishihara J, Fukunaga K, Ishihara A, Yuba E, Budina E, et al. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis. Arthritis Res Ther. 2019;21:298 pubmed publisher
Barbariga M, Vallone F, Mosca E, Bignami F, Magagnotti C, Fonteyne P, et al. The role of extracellular matrix in mouse and human corneal neovascularization. Sci Rep. 2019;9:14272 pubmed publisher
Chiarelli N, Carini G, Zoppi N, Ritelli M, Colombi M. Transcriptome analysis of skin fibroblasts with dominant negative COL3A1 mutations provides molecular insights into the etiopathology of vascular Ehlers-Danlos syndrome. PLoS ONE. 2018;13:e0191220 pubmed publisher
Caberlotto E, Ruiz L, Miller Z, Poletti M, Tadlock L. Effects of a skin-massaging device on the ex-vivo expression of human dermis proteins and in-vivo facial wrinkles. PLoS ONE. 2017;12:e0172624 pubmed publisher
Wisowski G, Kozma E, Bielecki T, Pudełko A, Olczyk K. Dermatan sulfate is a player in the transglutaminase 2 interaction network. PLoS ONE. 2017;12:e0172263 pubmed publisher
Martínez Aguilar J, Clifton Bligh R, Molloy M. Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy. Sci Rep. 2016;6:23660 pubmed publisher
Ueda K, Yoshimura K, Yamashita O, Harada T, Morikage N, Hamano K. Possible dual role of decorin in abdominal aortic aneurysm. PLoS ONE. 2015;10:e0120689 pubmed publisher
Syx D, Guillemyn B, Symoens S, Sousa A, Medeira A, Whiteford M, et al. Defective Proteolytic Processing of Fibrillar Procollagens and Prodecorin Due to Biallelic BMP1 Mutations Results in a Severe, Progressive Form of Osteogenesis Imperfecta. J Bone Miner Res. 2015;30:1445-56 pubmed publisher
Baasanjav S, Al Gazali L, Hashiguchi T, Mizumoto S, Fischer B, Horn D, et al. Faulty initiation of proteoglycan synthesis causes cardiac and joint defects. Am J Hum Genet. 2011;89:15-27 pubmed publisher
Yates C, Krishna P, Whaley D, Bodnar R, Turner T, Wells A. Lack of CXC chemokine receptor 3 signaling leads to hypertrophic and hypercellular scarring. Am J Pathol. 2010;176:1743-55 pubmed publisher
Li X, Pennisi A, Yaccoby S. Role of decorin in the antimyeloma effects of osteoblasts. Blood. 2008;112:159-68 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB143

SKU :

MAB143-100

product name :

Human Decorin Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human Decorin Antibody from R&D Systems is a mouse monoclonal antibody to Decorin. This antibody reacts with human,mouse. The Human Decorin Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.

target :

Decorin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

115402

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Simple Western 10 ug/mL

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Decorin, Gly17-Lys172, Accession # NP_598013.1

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human Decorin in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant mouse Decorin.

gene symbol :

DCN

top caption :

Detection of Human Decorin antibody by Western Blot.

accessionNumbers :

NP_598013.1

applications :

Simple Western,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

489 USD

alt names :

Bone proteoglycan II, CSCD, DCN, decorin, decorin proteoglycan, dermatan sulphate proteoglycans II, DSPG2, PG40, PGII, PG-II, PGS2, PG-S2, proteoglycan core protein, SLRR1B, SLRR1BPGS2, small leucine-rich protein 1B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage