product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat alpha -Smooth Muscle Actin Antibody
catalog :
MAB1420
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1A4
reactivity :
human, mouse, rat, dogs, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 139
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s2b
Kloth B, Mearini G, Weinberger F, Stenzig J, Geertz B, Starbatty J, et al. Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes. Sci Rep. 2022;12:8193 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1a
Mehatre S, Roy I, Biswas A, Prit D, Schouteden S, Huelsken J, et al. Niche-Mediated Integrin Signaling Supports Steady-State Hematopoiesis in the Spleen. J Immunol. 2021;206:1549-1560 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 2g
Jaworek C, Verel Yilmaz Y, Driesch S, Ostgathe S, Cook L, Wagner S, et al. Cohort Analysis of ADAM8 Expression in the PDAC Tumor Stroma. J Pers Med. 2021;11: pubmed publisher
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Hern xe1 ndez D, Morgan Schlicht S, Elli Clarke J, Daniszewski M, Karch C, Goate A, et al. Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation. Stem Cell Res. 2024;79:103495 pubmed publisher
Lewis P, Silajd x17e i x107 E, Smith H, Bates N, Smith C, Mancini F, et al. A secreted proteomic footprint for stem cell pluripotency. PLoS ONE. 2024;19:e0299365 pubmed publisher
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Lee D, Benvie A, Steiner B, Kolba N, Ford J, McCabe S, et al. Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue. Cell Rep. 2024;43:114169 pubmed publisher
Jocher J, Edenhofer F, M xfc ller S, Janssen P, Briem E, Geuder J, et al. Generation and characterization of two Vervet monkey induced pluripotent stem cell lines derived from fibroblasts. Stem Cell Res. 2024;75:103315 pubmed publisher
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Pires R, Dau T, Manu E, Shree N, Otto O. Switching in the expression pattern of actin isoforms marks the onset of contractility and distinct mechanodynamic behavior during cardiomyocyte differentiation. Physiol Rep. 2022;10:e15171 pubmed publisher
Chakravarty D, Ray A, Chander V, Mabalirajan U, Mondal P, Siddiqui K, et al. Systemic deficiency of vitronectin is associated with aortic inflammation and plaque progression in ApoE-Knockout mice. FASEB Bioadv. 2022;4:121-137 pubmed publisher
Mause S, Ritzel E, Deck A, Vogt F, Liehn E. Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular Homeostasis. Int J Mol Sci. 2022;23: pubmed publisher
Kazi T, Nagata A, Nakagawa T, Matsuzaki T, Inui S. Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation. Cells. 2022;11: pubmed publisher
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product information
brand :
R&D Systems
master code :
MAB1420
SKU :
MAB1420
product name :
Human/Mouse/Rat alpha -Smooth Muscle Actin Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat alpha -Smooth Muscle Actin Antibody from R&D Systems is a mouse monoclonal antibody to alpha-Smooth Muscle Actin. This antibody reacts with canine,human,mouse,primate - macaca mulatta (rhesus macaque),primate - papio anubis (olive baboon),rabbit,rat,transgenic mouse. The Human/Mouse/Rat alpha -Smooth Muscle Actin Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Western Blot,Multiplex Immunofluorescence,CyTof,Flow Cytometry,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready,Dual RNAscope ISH-IHC Compatible.
target :
alpha-Smooth Muscle Actin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
1A4
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1-0.25 ug/mL, Simple Western 10 ug/mL, Immunohistochemistry 3-25 ug/mL, Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready, Dual RNAscope ISH-IHC 0.5-25 ug/mL, Multiplex Immunofluorescence 0.5 ug/mL
host :
Mouse
immunogen :
Peptide corresponding to residues EEEDSTALVC of the N-term of human alpha -smooth muscle actin (1)
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Canine,Human,Mouse,Primate - Macaca mulatta (Rhesus Macaque),Primate - Papio anubis (Olive Baboon),Rabbit,Rat,Transgenic Mouse
specificity :
Detects human alpha -Smooth Muscle Actin.
gene symbol :
ACTA2
applications :
Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready,Dual RNAscope ISH-IHC Compatible,Multiplex Immunofluorescence,CyTof,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence
USD :
469 USD
alt names :
AAT6, ACTA2, Actin alpha 2, actin, alpha 2, smooth muscle, aorta, actin, aortic smooth muscle, ACTSA, ACTVS, alpha 2 actin, alpha SMA, alpha smooth muscle actin, alpha-actin-2, alpha-SMA, alphaSmooth Muscle Actin, a-sma, Cell growth-inhibiting gene 46 protein, growth-inhibiting gene 46, MYMY5, sma, smooth muscle actin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.