Human Fas/TNFRSF6/CD95 Antibody | R&D Systems MAB142 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Fas/TNFRSF6/CD95 Antibody

catalog :

MAB142

quantity :

500 ug (also 25 ug)

price :

559 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DX2

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Nelke J, Medler J, Weisenberger D, Beilhack A, Wajant H. CD40- and CD95-specific antibody single chain-Baff fusion proteins display BaffR-, TACI- and BCMA-restricted agonism. MAbs. 2020;12:1807721 pubmed publisher
Seirafian S, Prod homme V, Sugrue D, Davies J, Fielding C, Tomasec P, et al. Human cytomegalovirus suppresses Fas expression and function. J Gen Virol. 2014;95:933-9 pubmed publisher
Harris L, Keogh R, Wareing M, Baker P, Cartwright J, Aplin J, et al. Invasive trophoblasts stimulate vascular smooth muscle cell apoptosis by a fas ligand-dependent mechanism. Am J Pathol. 2006;169:1863-74 pubmed
Chopin V, Slomianny C, Hondermarck H, Le Bourhis X. Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1). Exp Cell Res. 2004;298:560-73 pubmed
Phillips D, Griffiths H. Ceramide induces a loss in cytosolic peroxide levels in mononuclear cells. Biochem J. 2003;375:567-79 pubmed
Savarese T, Campbell C, McQuain C, Mitchell K, Guardiani R, Quesenberry P, et al. Coexpression of oncostatin M and its receptors and evidence for STAT3 activation in human ovarian carcinomas. Cytokine. 2002;17:324-34 pubmed

product information

master code :

MAB142

SKU :

MAB142

product name :

Human Fas/TNFRSF6/CD95 Antibody

unit size :

500 ug (also 25 ug)

description :

The Human Fas/TNFRSF6/CD95 Antibody from R&D Systems is a mouse monoclonal antibody to Fas/TNFRSF6/CD95. This antibody reacts with human. The Human Fas/TNFRSF6/CD95 Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry,Functional Assay,Immunohistochemistry-Frozen,Immunohistochemistry,Western Blot.

target :

Fas/TNFRSF6/CD95

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

DX2

conjugate :

Unconjugated

host :

Mouse

immunogen :

L cells transfected with human Fas

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Fas in direct ELISAs and Western blots. Does not cross-react with rhCD27, rmCD27, rhCD30, rmCD30, rhCD40, rmCD40, rhDR3, rmDR3, rhHVEM, rmHVEM, rhLymphotoxin ▀R, rmLymphotoxin ▀R, rhTRAIL R1, rmTRAIL R1, rhTRAIL R2, rmTRAIL R2, rhTRAIL R3, or rhTRAIL R4,

gene symbol :

FAS

applications :

Flow Cytometry,Immunocytochemistry,Functional Assay,Immunohistochemistry-Frozen,Immunohistochemistry,Western Blot

extended description :

Clone DX2 was used by HLDA to establish CD designation

USD :

559 USD

product details :

Clone DX2 was used by HLDA to establish CD designation

alt names :

Apo-1, Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1, APT1FASTM, CD95, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage