Human Glut1 Antibody | R&D Systems MAB1418 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Glut1 Antibody

catalog :

MAB1418

quantity :

200 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

202915

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 28

Reference
J xfc rgens M, Claus M, Wingert S, Niemann J, Picard L, Hennes E, et al. Chronic stimulation desensitizes β2-adrenergic receptor responses in natural killer cells. Eur J Immunol. 2024;54:e2451299 pubmed publisher
Cho H, Kwon H, Sharma A, Lee S, Liu X, Miyamoto N, et al. Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target. Nat Commun. 2022;13:5974 pubmed publisher
McTernan P, Levitt D, Welsh D, Simon L, Siggins R, Molina P. Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells. Front Immunol. 2022;13:839390 pubmed publisher
Montero J, Calvo Jim xe9 nez E, Del Carmen S, Abad M, Oca xf1 a A, Pandiella A. Surfaceome analyses uncover CD98hc as an antibody drug-conjugate target in triple negative breast cancer. J Exp Clin Cancer Res. 2022;41:106 pubmed publisher
Neuperger P, Balog J, Tiszlavicz L, Fur xe1 k J, G xe9 mes N, Kotog xe1 ny E, et al. Analysis of the Single-Cell Heterogeneity of Adenocarcinoma Cell Lines and the Investigation of Intratumor Heterogeneity Reveals the Expression of Transmembrane Protein 45A (TMEM45A) in Lung Adenocarcinoma Cancer Patients. Cancers (Basel). 2021;14: pubmed publisher
Morrissey S, Zhang F, Ding C, Montoya Durango D, Hu X, Yang C, et al. Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming. Cell Metab. 2021;33:2040-2058.e10 pubmed publisher
Huang L, Bischoff J. Isolation of Stem Cells, Endothelial Cells and Pericytes from Human Infantile Hemangioma. Bio Protoc. 2020;10:e3487 pubmed publisher
Alföldi R, Balog J, Faragó N, Halmai M, Kotogány E, Neuperger P, et al. Single Cell Mass Cytometry of Non-Small Cell Lung Cancer Cells Reveals Complexity of In vivo And Three-Dimensional Models over the Petri-dish. Cells. 2019;8: pubmed publisher
Thaventhiran T, Wong W, Alghanem A, Alhumeed N, Aljasir M, Ramsey S, et al. CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program. Monoclon Antib Immunodiagn Immunother. 2019;38:60-69 pubmed publisher
Duette G, Pereyra Gerber P, Rubione J, Pérez P, Landay A, Crowe S, et al. Induction of HIF-1α by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation. MBio. 2018;9: pubmed publisher
Gualdoni G, Mayer K, Kapsch A, Kreuzberg K, Puck A, Kienzl P, et al. Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication. Proc Natl Acad Sci U S A. 2018;115:E7158-E7165 pubmed publisher
Masson J, Cherry C, Murphy N, Sada Ovalle I, Hussain T, Palchaudhuri R, et al. Polymorphism rs1385129 Within Glut1 Gene SLC2A1 Is Linked to Poor CD4+ T Cell Recovery in Antiretroviral-Treated HIV+ Individuals. Front Immunol. 2018;9:900 pubmed publisher
Vignali D, Cantarelli E, Bordignon C, Canu A, Citro A, Annoni A, et al. Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients With Type 1 Diabetes. Diabetes. 2018;67:936-945 pubmed publisher
Palmer C, Duette G, Wagner M, Henstridge D, Saleh S, Pereira C, et al. Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during inÂ vitro infection. FEBS Lett. 2017;591:3319-3332 pubmed publisher
Masson J, Murphy A, Lee M, Ostrowski M, Crowe S, Palmer C. Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy. PLoS ONE. 2017;12:e0183931 pubmed publisher
Varanasi S, Donohoe D, Jaggi U, Rouse B. Manipulating Glucose Metabolism during Different Stages of Viral Pathogenesis Can Have either Detrimental or Beneficial Effects. J Immunol. 2017;199:1748-1761 pubmed publisher
Yeoh H, Cheng A, Cherry C, Weir J, Meikle P, Hoy J, et al. Immunometabolic and Lipidomic Markers Associated With the Frailty Index and Quality of Life in Aging HIV+ Men on Antiretroviral Therapy. EBioMedicine. 2017;22:112-121 pubmed publisher
Rueda C, Rodríguez Perea A, Moreno Fernandez M, Jackson C, Melchior J, Davidson W, et al. High density lipoproteins selectively promote the survival of human regulatory T cells. J Lipid Res. 2017;58:1514-1523 pubmed publisher
Clow K, Short C, Hall J, Gendron R, Paradis H, Ralhan A, et al. High rates of glucose utilization in the gas gland of Atlantic cod (Gadus morhua) are supported by GLUT1 and HK1b. J Exp Biol. 2016;219:2763-73 pubmed publisher
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product information

brand :

R&D Systems

master code :

MAB1418

SKU :

MAB1418

product name :

Human Glut1 Antibody

unit size :

200 ug (also 25 ug)

seo description :

The Human Glut1 Antibody from R&D Systems is a mouse monoclonal antibody to Glut1. This antibody reacts with human,mouse. The Human Glut1 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunocytochemistry,CyTOF-ready.

target :

Glut1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

202915

conjugate :

Unconjugated

dilution :

Flow Cytometry 0.25 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human Glut1, Met1-Val492, Accession # AAA52571

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human Glut1. Stains human Glut1-transfected NS0 cells, but not NS0 control transfectants. Although Human Glut1 Antibody detects Glut1 on the surface of T cells (1, 2), it does not detect it on erythrocytes (5). The reason for this discrepancy is not understood, but may be related to conformational or post-translational modification differences.

gene symbol :

SLC2A1

top caption :

Detection of Glut1 antibody in HepG2 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

AAA52571

applications :

CyTOF-ready,Flow Cytometry,Immunohistochemistry,Immunocytochemistry

USD :

479 USD

alt names :

Choreoathetosis/Spasticity, Episodic (Paroxysmal Choreoathetosis), CSE, DYT17, DYT18, DYT9, EIG12, Glucose transporter type 1, erythrocyte/brain, GLUT-1, GLUT1DS, HepG2 glucose transporter, HTLVR, Human T-Cell Leukemia Virus (I and II) Receptor, MGC141895, MGC141896, PED, SLC2A1, solute carrier family 2 (facilitated glucose transporter), member 1, Solute Carrier Family 2 Member 1, solute carrier family 2, facilitated glucose transporter member 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage