Human/Mouse/Bovine Insulin Antibody | R&D Systems MAB1417 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Bovine Insulin Antibody

catalog :

MAB1417

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

182410

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 25

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 2e	Borg D, Faridi P, Giam K, Reeves P, Fotheringham A, McCarthy D, et al. Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model. Metabolites. 2021;11: pubmed publisher
	Terry T, Gigante E, Alexandre C, Brewer K, Engle S, Yue X, et al. Ciliary ARL13B prevents obesity in mice. bioRxiv. 2023;: pubmed publisher
	Wakabayashi Y, Miyatsuka T, Miura M, Himuro M, Taguchi T, Iida H, et al. STAT3 suppression and β-cell ablation enhance α-to-β reprogramming mediated by Pdx1. Sci Rep. 2022;12:21419 pubmed publisher
	Jiménez González M, Li R, Pomeranz L, Alvarsson A, Marongiu R, Hampton R, et al. Mapping and targeted viral activation of pancreatic nerves in mice reveal their roles in the regulation of glucose metabolism. Nat Biomed Eng. 2022;6:1298-1316 pubmed publisher
	Zhang X, Luo S, Wang M, Huang Q, Fang W, Li J, et al. IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells. Dev Cell. 2022;57:1496-1511.e6 pubmed publisher
	Lei L, Huan Y, Liu Q, Li C, Cao H, Ji W, et al. Morus alba L. (Sangzhi) Alkaloids Promote Insulin Secretion, Restore Diabetic β-Cell Function by Preventing Dedifferentiation and Apoptosis. Front Pharmacol. 2022;13:841981 pubmed publisher
	Brown M, Sen S, Mazzone A, Her T, Xiong Y, Lee J, et al. Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β cell function. Sci Adv. 2021;7:eabg6856 pubmed publisher
	Rui J, Deng S, Perdigoto A, Ponath G, Kursawe R, Lawlor N, et al. Tet2 Controls the Responses of β cells to Inflammation in Autoimmune Diabetes. Nat Commun. 2021;12:5074 pubmed publisher
	Lee S, Zhang J, Saravanakumar S, Flisher M, Grimm D, van der Meulen T, et al. Virgin β-Cells at the Neogenic Niche Proliferate Normally and Mature Slowly. Diabetes. 2021;70:1070-1083 pubmed publisher
	Cao H, Li C, Lei L, Wang X, Liu S, Liu Q, et al. Stachyose Improves the Effects of Berberine on Glucose Metabolism by Regulating Intestinal Microbiota and Short-Chain Fatty Acids in Spontaneous Type 2 Diabetic KKAy Mice. Front Pharmacol. 2020;11:578943 pubmed publisher
	Kojima M, Takahashi H, Kuwashiro T, Tanaka K, Mori H, Ozaki I, et al. Glucagon-Like Peptide-1 Receptor Agonist Prevented the Progression of Hepatocellular Carcinoma in a Mouse Model of Nonalcoholic Steatohepatitis. Int J Mol Sci. 2020;21: pubmed publisher
	Elizondo D, Brandy N, da Silva R, de Moura T, Ali J, Yang D, et al. Pancreatic islets seeded in a novel bioscaffold forms an organoid to rescue insulin production and reverse hyperglycemia in models of type 1 diabetes. Sci Rep. 2020;10:4362 pubmed publisher
	Alleva D, Rezaee M, Yip L, Ren G, Rosenberg J, Concepcion W, et al. Reversal of Hyperglycemia and Suppression of Type 1 Diabetes in the NOD Mouse with Apoptotic DNA Immunotherapy™ (ADi™), ADi-100. Biomedicines. 2020;8: pubmed publisher
	Ning F, Jensen N, Mi J, Lindstrom W, Balan M, Muhl L, et al. VEGF-B ablation in pancreatic β-cells upregulates insulin expression without affecting glucose homeostasis or islet lipid uptake. Sci Rep. 2020;10:923 pubmed publisher
	De Toni L, Guidolin D, De Filippis V, Peterle D, Rocca M, Di Nisio A, et al. SHBG141-161 Domain-Peptide Stimulates GPRC6A-Mediated Response in Leydig and β-Langerhans cell lines. Sci Rep. 2019;9:19432 pubmed publisher
	Fang Z, Weng C, Li H, Tao R, Mai W, Liu X, et al. Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes. Cell Rep. 2019;26:3132-3144.e7 pubmed publisher
	Jahan M, Johnström P, Selvaraju R, Svedberg M, Winzell M, Bernström J, et al. The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass. EJNMMI Res. 2018;8:113 pubmed publisher
	Borg D, Yap F, Keshvari S, Simmons D, Gallo L, Fotheringham A, et al. Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets. 2017;: pubmed publisher
	Bahrebar M, Soleimani M, Karimi M, Vahdati A, Yaghobi R. Generation of Islet-like Cell Aggregates from Human Adipose Tissue-derived Stem Cells by Lentiviral Overexpression of PDX-1. Int J Organ Transplant Med. 2015;6:61-76 pubmed
	Cucak H, Mayer C, Tonnesen M, Thomsen L, Grunnet L, Rosendahl A. Macrophage contact dependent and independent TLR4 mechanisms induce ?-cell dysfunction and apoptosis in a mouse model of type 2 diabetes. PLoS ONE. 2014;9:e90685 pubmed publisher
	Cucak H, Grunnet L, Rosendahl A. Accumulation of M1-like macrophages in type 2 diabetic islets is followed by a systemic shift in macrophage polarization. J Leukoc Biol. 2014;95:149-60 pubmed publisher
	Hagberg C, Mehlem A, Falkevall A, Muhl L, Fam B, Ortsäter H, et al. Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes. Nature. 2012;490:426-30 pubmed publisher
	Kalis M, Bolmeson C, Esguerra J, Gupta S, Edlund A, Tormo Badia N, et al. Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus. PLoS ONE. 2011;6:e29166 pubmed publisher
	Jin C, Li W, Xu F, Geng Z, He Z, Su J, et al. Conversion of immortal liver progenitor cells into pancreatic endocrine progenitor cells by persistent expression of Pdx-1. J Cell Biochem. 2008;104:224-36 pubmed
	Dowling P, O Driscoll L, O SULLIVAN F, Dowd A, Henry M, Jeppesen P, et al. Proteomic screening of glucose-responsive and glucose non-responsive MIN-6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress. Proteomics. 2006;6:6578-87 pubmed

product information

brand :

R&D Systems

master code :

MAB1417

SKU :

MAB1417

product name :

Human/Mouse/Bovine Insulin Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Bovine Insulin Antibody from R&D Systems is a rat monoclonal antibody to Insulin. This antibody reacts with bovine,human,mouse. The Human/Mouse/Bovine Insulin Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

Insulin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

182410

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Immunohistochemistry 0.5-25 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready

host :

Rat

immunogen :

E. coli -derived recombinant human Insulin

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Bovine,Human,Mouse

specificity :

Detects bovine, human, and mouse insulin.

gene symbol :

INS

top caption :

Insulin antibody in ssTC-6 Mouse Cell Line by Immunocytochemistry (ICC).

applications :

Intracellular Staining by Flow Cytometry,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

499 USD

alt names :

IDDM2, ILPR, INS, insulin, IRDN, MODY10, proinsulin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage