Human/Mouse/Rat/Chicken A2B5 Antibody | R&D Systems MAB1416 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat/Chicken A2B5 Antibody

catalog :

MAB1416

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

105

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 27

Reference
Takasugi M, Ohtani N, Takemura K, Emmrich S, Zakusilo F, Yoshida Y, et al. CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance. Cell Rep. 2023;42:113130 pubmed publisher
Ye D, Qu S, Yang Y, Wang Z, Wang Q, Liu W, et al. Intrauterine desensitization enables long term survival of human oligodendrocyte progenitor cells without immunosuppression. iScience. 2023;26:106647 pubmed publisher
Ye D, Wang Q, Yang Y, Chen B, Zhang F, Wang Z, et al. Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature Oligodendrocytes. Cell Mol Neurobiol. 2023;43:2337-2358 pubmed publisher
Titus H, Xu H, Robinson A, Patel P, Chen Y, Fantini D, et al. Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis. Glia. 2022;70:1950-1970 pubmed publisher
Zhou H, He Y, Wang Z, Wang Q, Hu C, Wang X, et al. Identifying the functions of two biomarkers in human oligodendrocyte progenitor cell development. J Transl Med. 2021;19:188 pubmed publisher
Kim K, Li C, Bunina D, Jeong H, Ghelman J, Yoon J, et al. Donor cell memory confers a metastable state of directly converted cells. Cell Stem Cell. 2021;28:1291-1306.e10 pubmed publisher
Yazdankhah M, Ghosh S, Shang P, Stepicheva N, Hose S, Liu H, et al. BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes. Autophagy. 2021;:1-20 pubmed publisher
Zepecki J, Snyder K, Moreno M, Fajardo E, Fiser A, Ness J, et al. Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor. Oncogene. 2019;38:1734-1750 pubmed publisher
Lee J, Laronde S, Collins T, Shapovalova Z, Tanasijevic B, McNicol J, et al. Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency. Cell Rep. 2017;19:20-35 pubmed publisher
Cha M, Kwon Y, Ahn H, Jeong H, Lee Y, Moon M, et al. Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's Disease. Stem Cells Transl Med. 2017;6:293-305 pubmed publisher
Li X, Aleardi A, Wang J, Zhou Y, Andrade R, Hu Z. Differentiation of Spiral Ganglion-Derived Neural Stem Cells into Functional Synaptogenetic Neurons. Stem Cells Dev. 2016;25:803-13 pubmed publisher
Moyon S, Dubessy A, Aigrot M, Trotter M, Huang J, Dauphinot L, et al. Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration. J Neurosci. 2015;35:4-20 pubmed publisher
Leite C, Silva N, Mendes S, Ribeiro A, de Faria J, LourenÃ§o T, et al. Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage. PLoS ONE. 2014;9:e111059 pubmed publisher
Robinson A, Rodgers J, Goings G, Miller S. Characterization of oligodendroglial populations in mouse demyelinating disease using flow cytometry: clues for MS pathogenesis. PLoS ONE. 2014;9:e107649 pubmed publisher
Macas J, Ku M, Nern C, Xu Y, Buhler H, Remke M, et al. Generation of neuronal progenitor cells in response to tumors in the human brain. Stem Cells. 2014;32:244-57 pubmed publisher
Najm F, Lager A, Zaremba A, Wyatt K, Caprariello A, Factor D, et al. Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat Biotechnol. 2013;31:426-33 pubmed publisher
Werbowetski Ogilvie T, Morrison L, Fiebig Comyn A, Bhatia M. In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation. Stem Cells. 2012;30:392-404 pubmed publisher
Walczak P, All A, Rumpal N, Gorelik M, Kim H, Maybhate A, et al. Human glial-restricted progenitors survive, proliferate, and preserve electrophysiological function in rats with focal inflammatory spinal cord demyelination. Glia. 2011;59:499-510 pubmed publisher
Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi Takagi A, et al. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci U S A. 2010;107:5622-7 pubmed publisher
Todorich B, Zhang X, Slagle Webb B, Seaman W, Connor J. Tim-2 is the receptor for H-ferritin on oligodendrocytes. J Neurochem. 2008;107:1495-505 pubmed publisher
Dobson N, Zhou Y, Flint N, Armstrong R. Musashi1 RNA-binding protein regulates oligodendrocyte lineage cell differentiation and survival. Glia. 2008;56:318-30 pubmed
Chen H, Kintner D, Jones M, Matsuda T, Baba A, Kiedrowski L, et al. AMPA-mediated excitotoxicity in oligodendrocytes: role for Na(+)-K(+)-Cl(-) co-transport and reversal of Na(+)/Ca(2+) exchanger. J Neurochem. 2007;102:1783-1795 pubmed publisher
Kang S, Cho M, Seo H, Yoon C, Oh S, Choi Y, et al. Efficient induction of oligodendrocytes from human embryonic stem cells. Stem Cells. 2007;25:419-24 pubmed
Lee D, Yu K, Rho J, Lee E, Han J, Koo D, et al. Cyclopamine treatment of human embryonic stem cells followed by culture in human astrocyte medium promotes differentiation into nestin- and GFAP-expressing astrocytic lineage. Life Sci. 2006;80:154-9 pubmed
Ni H, Hu S, Sheng W, Olson J, Cheeran M, Chan A, et al. High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells. Brain Res Dev Brain Res. 2004;152:159-69 pubmed
Rosin C, Bates T, Skaper S. Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. J Neurochem. 2004;90:1173-85 pubmed
Tsai H, Tessier Lavigne M, Miller R. Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal. Development. 2003;130:2095-105 pubmed

product information

master code :

MAB1416

SKU :

MAB1416

product name :

Human/Mouse/Rat/Chicken A2B5 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat/Chicken A2B5 Antibody from R&D Systems is a mouse monoclonal antibody to A2B5. This antibody reacts with avian - chicken,chicken,human,mouse,rat. The Human/Mouse/Rat/Chicken A2B5 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready.

target :

A2B5

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

105

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Embryonic chicken retinal cells

isotype :

IgM

purity :

IgM-specific Affinity-purified from hybridoma culture supernatant

species :

Avian - Chicken,Chicken,Human,Mouse,Rat

specificity :

Recognizes the A2B5 cell surface ganglioside epitope found on type II astrocytes, cells involved in gliogenesis, and cells committed to the oligodendrocyte lineage (1-4).

top caption :

Detection of A2B5 antibody in NTera-2 Human Cell Line antibody by Flow Cytometry.

applications :

Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready

USD :

489 USD

alt names :

A2B5 marker

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage