Human B7-2/CD86 MAb (Clone 37301) | R&D Systems MAB141 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human B7-2/CD86 MAb (Clone 37301)

catalog :

MAB141

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

37301

reactivity :

human

application :

western blot, neutralization, flow cytometry

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...	Tagawa T, Albanese M, Bouvet M, Moosmann A, Mautner J, Heissmeyer V, et al. Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing. J Exp Med. 2016;213:2065-80 pubmed publisher
	Li J, Xu S, Zhao Y, Yu S, Ge L, Xu B. Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord. Mol Med Rep. 2018;18:4969-4977 pubmed publisher
	He S, Wu C, Xiao J, Li D, Sun Z, Li M. Endothelial extracellular vesicles modulate the macrophage phenotype: Potential implications in atherosclerosis. Scand J Immunol. 2018;87:e12648 pubmed publisher
	Qu D, Sun J, Zhao L, Wang Q, Shao Q, Kong B, et al. Human trophoblast cells induced MDSCs from peripheral blood CD14(+) myelomonocytic cells via elevated levels of CCL2. Cell Mol Immunol. 2016;13:615-27 pubmed publisher
	Mao C, Mou X, Zhou Y, Yuan G, Xu C, Liu H, et al. Tumor-activated TCR??? T cells from gastric cancer patients induce the antitumor immune response of TCR??? T cells via their antigen-presenting cell-like effects. J Immunol Res. 2014;2014:593562 pubmed publisher
	Cavel O, Shomron O, Shabtay A, Vital J, Trejo Leider L, Weizman N, et al. Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor. Cancer Res. 2012;72:5733-43 pubmed publisher
	Weissmüller S, Semmler L, Kalinke U, Christians S, Muller Berghaus J, Waibler Z. ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation. Blood. 2012;119:6268-77 pubmed publisher
	Tso G, Law H, Tu W, Chan G, Lau Y. Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells. Stem Cells. 2010;28:939-54 pubmed publisher
	El Fakhry Y, Alturaihi H, Diallo D, Merhi Y, Mourad W. Critical role of lipid rafts in CD154-mediated T cell signaling. Eur J Immunol. 2010;40:770-9 pubmed publisher
	van der Vliet H, Wang R, Yue S, Koon H, Balk S, Exley M. Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells. J Immunol. 2008;180:7287-93 pubmed
	Sakthivel P, Shively V, Kakoulidou M, Pearce W, Lefvert A. The soluble forms of CD28, CD86 and CTLA-4 constitute possible immunological markers in patients with abdominal aortic aneurysm. J Intern Med. 2007;261:399-407 pubmed
	Hock B, Patton W, Budhia S, Mannari D, Roberts P, McKenzie J. Human plasma contains a soluble form of CD86 which is present at elevated levels in some leukaemia patients. Leukemia. 2002;16:865-73 pubmed

product information

brand :

R&D Systems

master code :

MAB141

SKU :

MAB141-100

product name :

Human B7-2/CD86 MAb (Clone 37301)

description :

The Human B7-2/CD86 MAb (Clone 37301) from R&D Systems is a mouse monoclonal antibody to B7-2/CD86. This antibody reacts with human. The Human B7-2/CD86 MAb (Clone 37301) has been validated for the following applications: Western Blot, Flow Cytometry, Neutralization, CyTOF-ready, Knockout Validated.

target :

B7-2/CD86

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

37301

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human B7-2/CD86, Ala23-His244, Accession # P42081

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human B7-2/CD86 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) B7-1, recombinant mouse B7-2, recombinant rat B7-2, rhB7-H1, rhB7-H2, rhB7-H3, rhB7-H3b, rhB7-H4, or rhB7-L2 is observed.

gene symbol :

CD86

details of functionality :

ActivityAssaywCitation not found None None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB141

accessionNumbers :

P42081

applications :

Western Blot, Flow Cytometry, Neutralization, CyTOF-ready, Knockout Validated

2020 USD :

339

2021 USD :

359 USD

alt names :

Activation B7-2 antigen, B70, B72, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86, CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.