Human SOST/Sclerostin Antibody | R&D Systems MAB1406 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human SOST/Sclerostin Antibody

catalog :

MAB1406

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

220902

reactivity :

human

application :

western blot, ELISA

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4e	Ye W, Wang Y, Mei B, Hou S, Liu X, Wu G, et al. Computational and functional characterization of four SNPs in the SOST locus associated with osteoporosis. Bone. 2018;108:132-144 pubmed publisher
	Stapledon C, Tsangari H, Solomon L, Campbell D, Hurtado P, Krishnan R, et al. Human osteocyte expression of Nerve Growth Factor: The effect of Pentosan Polysulphate Sodium (PPS) and implications for pain associated with knee osteoarthritis. PLoS ONE. 2019;14:e0222602 pubmed publisher
	Pereira R, Valta H, Tumber N, Salusky I, Jalanko H, MÃ¤kitie O, et al. Altered Osteocyte-Specific Protein Expression in Bone after Childhood Solid Organ Transplantation. PLoS ONE. 2015;10:e0138156 pubmed publisher
	Pereira R, Juppner H, Gales B, Salusky I, Wesseling Perry K. Osteocytic protein expression response to doxercalciferol therapy in pediatric dialysis patients. PLoS ONE. 2015;10:e0120856 pubmed publisher
	Jilka R, O Brien C, Bartell S, Weinstein R, Manolagas S. Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms. J Bone Miner Res. 2010;25:2427-37 pubmed publisher
	Mödder U, Clowes J, Hoey K, Peterson J, McCready L, Oursler M, et al. Regulation of circulating sclerostin levels by sex steroids in women and in men. J Bone Miner Res. 2011;26:27-34 pubmed publisher
	Appel H, Ruiz Heiland G, Listing J, Zwerina J, Herrmann M, Mueller R, et al. Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis. Arthritis Rheum. 2009;60:3257-62 pubmed publisher
	Jager A, Gotz W, Lossdörfer S, Rath Deschner B. Localization of SOST/sclerostin in cementocytes in vivo and in mineralizing periodontal ligament cells in vitro. J Periodontal Res. 2010;45:246-54 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB1406

SKU :

MAB1406-100

product name :

Human SOST/Sclerostin Antibody

description :

The Human SOST/Sclerostin Antibody from R&D Systems is a mouse monoclonal antibody to SOST/Sclerostin. This antibody reacts with human. The Human SOST/Sclerostin Antibody has been validated for the following applications: Western Blot, ELISA Capture (Matched Antibody Pair).

target :

SOST/Sclerostin

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

220902

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human SOST/Sclerostin, Gln24-Tyr213, Accession # Q9BQB4

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human SOST/Sclerostin in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse SOST is observed.

gene symbol :

SOST

catalog number base :

MAB1406

accessionNumbers :

Q9BQB4

applications :

Western Blot, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

alt names :

sclerostin, VBCHsclerosteosis

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.