Human IL-23R Antibody | R&D Systems MAB14001 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-23R Antibody

catalog :

MAB14001

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

218213

reactivity :

human, rhesus macaque

application :

western blot, ELISA, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 9

Reference
Sun R, Abraham C. IL23 Promotes Antimicrobial Pathways in Human Macrophages, Which Are Reduced With the IBD-Protective IL23R R381Q Variant. Cell Mol Gastroenterol Hepatol. 2020;: pubmed publisher
Liu D, Xing S, Wang W, Huang X, Lin H, Chen Y, et al. Prognostic value of serum soluble interleukin-23 receptor and related T-helper 17 cell cytokines in non-small cell lung carcinoma. Cancer Sci. 2020;111:1093-1102 pubmed publisher
Yu R, Brazaitis J, Gallagher G. The human IL-23 receptor rs11209026 A allele promotes the expression of a soluble IL-23R-encoding mRNA species. J Immunol. 2015;194:1062-8 pubmed publisher
Shen H, Wang Y, Chen C, Frencher J, Huang D, Yang E, et al. Th17-related cytokines contribute to recall-like expansion/effector function of HMBPP-specific VÎ³2VÎ´2 T cells after Mycobacterium tuberculosis infection or vaccination. Eur J Immunol. 2015;45:442-51 pubmed publisher
Longhi M, Moss A, Bai A, Wu Y, Huang H, Cheifetz A, et al. Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease. PLoS ONE. 2014;9:e87956 pubmed publisher
Ansari A, Reimann K, Mayne A, Takahashi Y, Stephenson S, Wang R, et al. Blocking of ?4?7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. J Immunol. 2011;186:1044-59 pubmed publisher
Yu R, Gallagher G. A naturally occurring, soluble antagonist of human IL-23 inhibits the development and in vitro function of human Th17 cells. J Immunol. 2010;185:7302-8 pubmed publisher
Cabezón R, Sintes J, Llinàs L, Benitez Ribas D. Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol Lett. 2011;134:167-73 pubmed publisher
Guttman Yassky E, Lowes M, Fuentes Duculan J, Zaba L, Cardinale I, Nograles K, et al. Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis. J Immunol. 2008;181:7420-7 pubmed

product information

master code :

MAB14001

SKU :

MAB14001

product name :

Human IL-23R Antibody

unit size :

100 ug (also 25 ug)

description :

The Human IL-23R Antibody from R&D Systems is a mouse monoclonal antibody to IL-23R. This antibody reacts with human,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque),primate - macaca mulatta (rhesus macaque). The Human IL-23R Antibody has been validated for the following applications: Bioassay,ELISA (Capture),ELISA Development,ELISA Development (Capture),Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen.

target :

IL-23R

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

218213

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IL-23 R, Gly24-Ile354, Accession # Q5VWK5

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque),Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human IL-23 R in direct ELISAs and Western blots. Does not cross-react with recombinant mouse (rm) IL-23 R.

gene symbol :

IL23R

top caption :

Detection of Human IL-23 R antibody by Western Blot.

accessionNumbers :

Q5VWK5

applications :

Bioassay,ELISA (Capture),ELISA Development,ELISA Development (Capture),Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen

USD :

469 USD

alt names :

IBD17, IL-23 R, IL-23 receptor, IL23R, IL-23R, interleukin 23 receptor, interleukin-23 receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage